Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin by Rance Nault (3847747)

“…Phosphatidylserines, phosphatidylethanolamines, phosphatidic acids, and cardiolipins decreased 4.1-, 5.0-, 5.4- and 7.4-fold, respectively, while ceramides increased 6.6-fold. …”

Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin by Rance Nault (3847747)

“…Phosphatidylserines, phosphatidylethanolamines, phosphatidic acids, and cardiolipins decreased 4.1-, 5.0-, 5.4- and 7.4-fold, respectively, while ceramides increased 6.6-fold. …”

The performance and long-term stability of low-cost separators in single-chamber bottle-type microbial fuel cells by Sanath Kondaveeti (3849310)

“…MFC operations with other size-selective separators such as SPPS, PPS, and cellulose esters exhibited power densities of 261, 231, and 250 mW/m², respectively. During a 280-day operation, initial power density of PP80 (278 mW/m²) was decreased to 257 mW/m², but this decrease was smaller than with others (Nafion: 265–230 mW/m²; PP100: 220–126 mW/m²). …”

Free energy properties in cultured neural networks. by Takuya Isomura (839119)

“…<b>(D)</b> The change in 〈<i>U</i>〉, <i>H</i>, and <i>F</i> (trial 1 vs. trial 100). After training, the expectation of internal energy decreased (*, <i>p</i> = 0.023; <i>n</i> = 23 cultures), Shannon entropy significantly increased (****, <i>p</i> < 10⁻⁴; <i>n</i> = 23 cultures), and free energy significantly decreased (****, <i>p</i> < 10⁻⁴; <i>n</i> = 23 cultures). …”

DataSheet_1_Effects of the neurotoxin β-N-methylamino-L-alanine (BMAA) on the early embryonic development of marine shellfish and fish.docx by Yilei Fu (14287574)

“…A sustained and dose-dependent decrease in heart rate was apparent in marine medaka embryos at 9-days post fertilization following BMAA exposure. …”

Data Sheet 1_Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutatio... by Zeyu Yang (8690226)

“…Phosphorylation causes a 2-3 fold decrease of affinity of cTn for Ca²⁺ associated with a higher rate of Ca²⁺ dissociation from cTnC leading to a faster relaxation rate of the cardiac muscle (lusitropy). …”

Datasheet1_Post-procedural and long-term functional outcomes of jailed side branches in stented coronary bifurcation lesions assessed with side branch Murray law–based quantitative... by Ke Xu (134879)

“…</p>Results<p>At follow-up, 8 (2.6%), 16 (5.1%), 61 (19.5%), and 228 (72.8%) SBs had a TIMI flow grade of 0, 1, 2, and 3, respectively. …”

Transfer of OVA-expressing tumor cells into wild-type mice results in loss of antigen and induction of MHC on lymphoma cells. by Armin Gerbitz (174530)

“…(C) Inoculation of 291OVA cells, but not of 291PC cells, into wild-type (n = 5) and GFP-transgenic mice (n = 5) significantly induced MHC class I (left panel) and class II (right panel) in outgrowing lymphoma cells. …”

Arkadia Ubiquitinates P-Smad2 and Mediates Its Degradation via the Proteasome by Konstantinos J Mavrakis (25033)

“…(E) Graphical representation of relative endogenous P-Smad2 levels normalized against the housekeeping gene Tubulin shows approximately a 2.5-fold reduction of P-Smad2 in Arkadia-expressing MEFs in the presence of DMSO when compared to MG132. …”

Protocol: Temporary Pacemaker Verification and Troubleshooting by Jill Ley (4090672)

“…<p>(Figure 1)</p> <p>(Figure 2)</p> <p><strong>Determining the Stimulation Threshold</strong></p> <ul> <li>NOTE: a paced rhythm must be present and patient stable</li> <li>From 100% pacing, gradually decrease output for A or V, while watching monitor until you lose capture</li> <li>Now gradually increase output until 1:1 capture returns – this is the stimulation threshold</li> <li>This is the lowest amount of energy that will reliably capture the heart and pace</li> <li>Set mA 1.5-3 times above this threshold value for safety</li> <li>Repeat for other circuit (A or V)</li> <li>Note: the stimulation threshold should be checked DAILY by the MD/NP when pacing is in use; in the event 
the threshold value is rising, discuss with surgeon to determine if alternative pacing system is needed</li> </ul> <p><strong>Determining the Sensing Threshold</strong></p> <ul> <li>Note: the patient must have an underlying rhythm and tolerate a brief period without pacing to perform</li> <li>Set RATE at least 10 bpm below patient’s intrinsic heart rate (to allow sensing)</li> <li>Set OUTPUT at 0.1 mA (to avoid competitive pacing when device is made asynchronous briefly)</li> <li>Highlight SENSITIVITY (under Menu 1)</li> <li>Decrease SENSITIVITY: Slowly turn dial counter-clockwise until pace indicator flashes regularly (asynchronously)</li> <li>Increase SENSITIVITY: Slowly turn dial clockwise until sense indicator flashes again (when sensing resumes, this is the sensing threshold – the smallest complex that is reliably recognized, thus inhibiting the device)</li> <li>Set SENSITIVITY < half this threshold value for safety</li> <li>Repeat for other circuit (A or V)</li> <li>Restore previous rate and output values</li> </ul> <p><strong>Rapid Atrial (Overdrive) Pacing – PERFORMED BY MD/NP/CNS ONLY</strong></p> <ul> <li>Used to “overdrive pace” and terminate some atrial reentrant tachyarrhythmias, especially atrial flutter</li> <li>ALWAYS VERIFY correct wire connections to avoid stimulating the ventricles at a rapid rate!…”

Data_Sheet_1_The combined impact of redcedar encroachment and climate change on water resources in the Nebraska Sand Hills.docx by Yaser Kishawi (12959564)

“…The most-likely climate projection indicates that a warming pattern will be expected with a 4.1°C increase in average over the 100-year period, and this will be associated with lower-than-normal precipitation (P). …”

DataSheet_2_Activation of thousands of genes in the lungs and kidneys by sepsis is countered by the selective nuclear blockade.pdf by Huan Qiao (325643)

“…Moreover, 5,483 significantly expressed genes in sepsis are increased or decreased in the kidneys, the site of acute injury (AKI). …”

DataSheet_1_Activation of thousands of genes in the lungs and kidneys by sepsis is countered by the selective nuclear blockade.pdf by Huan Qiao (325643)

“…Moreover, 5,483 significantly expressed genes in sepsis are increased or decreased in the kidneys, the site of acute injury (AKI). …”

Abundance, relative frequency, and influence of 182 virulence factors used to classify 12,337 <i>S</i>. enterica genomes from human, beef, and bovine sources into two virulence gro... by Gavin J. Fenske (17583323)

“…<p>Points represent the square root mean decrease Gini impurity and natural log relative frequency (Cluster 1/Cluster 2–5) of each virulence factor, with diameter proportional to the number of isolates (min: 11, max: 11,653) carrying at least one copy of the virulence gene. …”

Expression levels of p115RhoGEF affect cell migration. by Swapnil S. Kher (513448)

“…Migration of 5 cells was measured in each experiment and data was pooled from three individual experiments. p115-OE MDA-MB-231 cells displayed decreased migration as compared to control cells that expressed GFP alone. …”

Metabolome and Proteome Profiling of Complex I Deficiency Induced by Rotenone by Ina Gielisch (1348827)

“…Pathway and network analyses revealed that the respiratory chain was highly deregulated, with metabolites such as FMN, FAD, NAD⁺, and ADP, direct players of the OXPHOS system, and metabolites of the TCA cycle decreased up to 100-fold. Synthesis of functional iron–sulfur clusters, which are of central importance for the electron transfer chain, and degradation products like bilirubin were also significantly reduced. …”

Metabolome and Proteome Profiling of Complex I Deficiency Induced by Rotenone by Ina Gielisch (1348827)

“…Pathway and network analyses revealed that the respiratory chain was highly deregulated, with metabolites such as FMN, FAD, NAD⁺, and ADP, direct players of the OXPHOS system, and metabolites of the TCA cycle decreased up to 100-fold. Synthesis of functional iron–sulfur clusters, which are of central importance for the electron transfer chain, and degradation products like bilirubin were also significantly reduced. …”

Metabolome and Proteome Profiling of Complex I Deficiency Induced by Rotenone by Ina Gielisch (1348827)

“…Pathway and network analyses revealed that the respiratory chain was highly deregulated, with metabolites such as FMN, FAD, NAD⁺, and ADP, direct players of the OXPHOS system, and metabolites of the TCA cycle decreased up to 100-fold. Synthesis of functional iron–sulfur clusters, which are of central importance for the electron transfer chain, and degradation products like bilirubin were also significantly reduced. …”

Metabolome and Proteome Profiling of Complex I Deficiency Induced by Rotenone by Ina Gielisch (1348827)

“…Pathway and network analyses revealed that the respiratory chain was highly deregulated, with metabolites such as FMN, FAD, NAD⁺, and ADP, direct players of the OXPHOS system, and metabolites of the TCA cycle decreased up to 100-fold. Synthesis of functional iron–sulfur clusters, which are of central importance for the electron transfer chain, and degradation products like bilirubin were also significantly reduced. …”

Metabolome and Proteome Profiling of Complex I Deficiency Induced by Rotenone by Ina Gielisch (1348827)

“…Pathway and network analyses revealed that the respiratory chain was highly deregulated, with metabolites such as FMN, FAD, NAD⁺, and ADP, direct players of the OXPHOS system, and metabolites of the TCA cycle decreased up to 100-fold. Synthesis of functional iron–sulfur clusters, which are of central importance for the electron transfer chain, and degradation products like bilirubin were also significantly reduced. …”