Sensitivity and specificity of fusion gene predictions. by Ali Bashir (44572)

“…<p>(A) Number of false positive (FP) and true positive (TP) fusion gene predictions for a simulated genome with 100 translocations and 10,000 paired reads. …”

Psychological Distress, Depression, Anxiety, and Burnout among International Humanitarian Aid Workers: A Longitudinal Study by Barbara Lopes Cardozo (136718)

“…We performed bivariate regression analyses at three time points. We fitted generalized estimating equation multivariable regression models for the longitudinal analyses.…”

Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing by Joshua N. Farr (799622)

“…Further, of the 21 unique genes altered in bone by E therapy, the expression of <i>INHBB</i> (encoding for the inhibin, beta B polypeptide), which decreased with aging (by 0.6-fold), was restored to young adult levels in response to E therapy. …”

Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor by Roberta Sessa Stilhano (328847)

“…In the SHR’s TA, AT1 protein expression was 23.5-fold higher than in WR without injury, but no difference was observed in the angiotensin II receptor type 2 (AT2) protein expression. …”

Table_1_High-risk screening of late-onset Pompe disease: A different early portrait in China.XLSX by Kexin Jiao (4926730)

“…The creatine kinase (CK) level ranged from normal to no more than 5-fold the upper normal limit (UNL). LOPD with isolated hyperCKemia was not identified.…”

Molecular classification of renal cell carcinoma subtypes using microRNA signatures by Apostolos Zaravinos (542199)

“…<p>Background: Renal cell carcinoma (RCC) is composed of various morphologically and cytogenetically distinct subtypes, the most prevalent of which are clear cell RCC (ccRCC, 75-80%), papillary RCC (papRCC, 10-15%) and chromophobe RCC (chRCC, 5%). Upper urinary tract urothelial cell carcinomas (UUT-UCCs) are uncommon and account for only 5-10% of urothelial carcinomas. …”

Supplementary Material for: SRS06, a New Semisynthetic Andrographolide Derivative with Improved Anticancer Potency and Selectivity, Inhibits Nuclear Factor-κB Nuclear Binding in th... by Lim J.C.W. (4150654)

“…The DNA fragmentation assay indicated that the main mode of cell death of SRS06-treated A549 cells was via apoptosis. At 5 µmol/l the compound decreased NF-κB protein expression and caused a significant reduction in the nuclear p65 DNA binding activity. …”

Transgenic mice with cysteine mutations have defects in T cell development in the thymus. by Yibing Wang (204330)

“…<i>p</i> values were obtained from <i>t</i> tests. In some cases, fold decreases are indicated.</p>…”

Group B Streptococcal Infection of the Choriodecidua Induces Dysfunction of the Cytokeratin Network in Amniotic Epithelium: A Pathway to Membrane Weakening by Jeroen P. Vanderhoeven (531499)

“…Ten chronically catheterized pregnant monkeys (<i>Macaca nemestrina</i>) at 118–125 days gestation (term = 172 days) received choriodecidual inoculation of either GBS (n = 5) or saline (n = 5). Cesarean section was performed in the first week after GBS or saline inoculation. …”

Data_Sheet_1_MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy.pdf by Yong Zeng (203681)

“…HRMECs were exposed to 5.5 mmol/L of glucose (normal control), 5.5 mmol/L of glucose and 24.5 mmol/L of mannitol (osmotic pressure control), 30 mmol/L of glucose [hyperglycemia (HG)], 150 μmol/L of CoCl₂ (hypoxia), and 30 mmol/L of glucose plus 150 μmol/L of CoCl₂ (HG-CoCl₂). …”

Differential proteomes of WT and Δ<i>tktA</i>, Δ<i>rpe and ΔrpiA</i> mutants. by Héloise Rytter (11218693)

“…The abscissa reports the fold change in logarithmic scale (difference), the ordinate the–log(pvalue). …”

Transposon disruption of candidate macrophage pathogenesis genes. by Dustin R. Long (11565529)

“…<p>Fold-difference in measurements of macrophage invasion, relative to in-batch testing of the parental JE2 strain (A), and macrophage intracellular survival (B) for specified transposon mutants. …”

Comparison of whole genome prediction accuracy across generations using parametric and semi parametric methods by Abbas Atefi (10414497)

“…A historical population of 1000 individuals with equal sex ratio was simulated for 100 generations at constant size. …”

Direct pathways of E2 on MCF-7 mammosphere proliferation. by Ji-Won Jung (194917)

“…<p>(A) 100 nM ICI 182,780 suppressed the effect of E2 on increment of the size and number of mammospheres. …”

The mechanistic model training and test performance on multiple omics datasets show qualitative and quantitative agreement. by Cemal Erdem (11054081)

“…The circles with error bars are the corresponding RPPA data points. The dashed black lines are the trajectories for “best-fit” parameter sets. …”

Quantitative Phosphoproteomics of Murine <i>Fmr1</i>-KO Cell Lines Provides New Insights into FMRP-Dependent Signal Transduction Mechanisms by Katarina Matic (1743595)

“…We quantify FMRP-related changes in the levels of 5,023 proteins and 6,133 phosphorylation events and map them onto major signal transduction pathways. …”

Endothelial cells in co-culture with vascular smooth muscle cells generate capillary-like networks. by Lasse Evensen (263932)

“…<p>(A) Live cell fluorescence microscopy of GFP-expressing HUVEC cell capillary-like network (green) after 5 days in co-culture with PA-vSMC (unlabeled). …”

Influential genomes and their combined effect. by Eva S. Deutekom (7321661)

“…The colour of the scatter plot points is according to the cosine distance to human, with a maximum cosine distance found to be 0.57. …”

Aptamers U2 and U8 target EGFRvIII specifically. by Xidong Wu (531467)

“…Lanes (left to right): 1, GN with U87MG cell lysate; 2, GN with U87-EGFRvIII cell lysate; 3, U2 with U87-EGFRvIII cell lysate; 4, U8 with U87-EGFRvIII cell lysate; 5, U2 with U87MG cell lysate; 6, U8 with U87MG cell lysate. …”

Clinical and virological profiles of TriD9 vaccine trial group. by Jodi K. Craigo (421284)

“…Febrile episodes were defined by a achieving a combination of two-three features such as: rectal temperature above 39°C in conjunction with thrombocytopenia (platelet decrease of ≥70,000/µl of whole blood), EIAV viral load ≥10⁵ as well as other clinical signs of EIA. …”