Image2_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.JPEG by Emily M. J. Fennell (6654536)

“…Notably, this included the downregulation of many mitochondrial processes and proteins, including mitochondrial translation and mitochondrial matrix proteins. We performed a large-scale transcriptomic analysis of WT SUM159 cells, identifying ∼7,700 transcripts (746 and 1,100 significantly increasing, 795 and 1,013 significantly decreasing in ONC201 and TR-57 treated cells, respectively). …”

Image6_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.JPEG by Emily M. J. Fennell (6654536)

“…Notably, this included the downregulation of many mitochondrial processes and proteins, including mitochondrial translation and mitochondrial matrix proteins. We performed a large-scale transcriptomic analysis of WT SUM159 cells, identifying ∼7,700 transcripts (746 and 1,100 significantly increasing, 795 and 1,013 significantly decreasing in ONC201 and TR-57 treated cells, respectively). …”

Sections of testis from 6 month old male medaka stained with H&E. by Hilary D. Miller (29470)

“…F: Animal exposed to 10.0 µg/L EE2 for 14 days has a severe thickening of the interstitium, increased vacuolization, and an overall decrease in germinal epithelium. …”

Replacement of chicken skin with canola oil in chicken nuggets by Sandra Tiemi Seó (16453032)

“…There was a decrease in AI (T0%-raw vs. T100%-fried, 0.39 vs. 0.10) and IT (T0%-raw vs. …”

Measured influence and the influence ratio. by Keiji Ota (7352777)

“…</b> Normative BDT influence and measured influence. We order the sample points for each sample point from 1 (the lowest) to either 5 or 30 (the highest) depending on sample size. …”

SIV-specific CD8 T cell response localizes to the gut and secondary lymphoid tissues during SIVΔnef vaccination. by Sama Adnan (693011)

“…*The fold change between weeks 5 and 20 for the ileum was based on one animal at each time point. …”

Temporal profiles of the key BO-NN features. by Julia Berezutskaya (9080269)

“…Per feature, a black line shows the time point where the autocorrelation drops below .5. <b>(b)</b> The accuracy of predicting the activity of the key BO-NN features from a set of speech features: speechON, sound intensity, pitch and frequency values for the first and second formants. …”

The <i>Citrobacter rodentium</i> type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses by Cedric N. Berger (4544008)

“…<i>rodentium</i>. This overlapped with a decrease in STAT3 phosphorylation in IECs. Importantly, while the reduced CCH and abundance of antimicrobial proteins during Δ<i>espO</i> infection did not affect <i>C</i>. …”

EFFECT OF WATER DEFICIT AND ABSCISIC ACID ON PHOTOSYNTHETIC AND ANTIOXIDANT METABOLISM IN SEEDLINGS OF Calophyllum brasiliense (CAMBESS.) by Lucas Coutinho Reis (6511265)

“…The decrease in stomatal conductance was accompanied by a decrease in photosynthetic and transpiration rates, but seedlings treated with 10 µM ABA presented a higher photosynthetic rate than the remaining treatments under water deficit. …”

The TATA box score and GC content versus location on the promoters. by Yuval Tabach (63080)

“…Scores above −10.4 were identified as hits and marked by a point whose horizontal coordinate represents the location of the hit and the vertical coordinate represents the value of its score. …”

Effects of positive end-expiratory pressure (PEEP) on venous return and cardiac output by Thomas Luecke (62130)

Muscle fiber CSAs of the soleus and EDL muscles in the GH-administered SDRs treated with dexamethasone, BCAA or both. by Hikaru Nishida (757003)

“…Dex-treated group. D. Dex elicited a decrease in the CSAs of the EDL muscles in the GH-treated SDRs. …”

SCD1 dynamics are altered in response to RSV. by Cristina Rojas (667363)

“…The results are shown as the mean of the fold change ± SD of three independent experiments. …”

Specificity of new binding sites tested via EMSA and luciferase assays. by Raquel Castellanos (559734)

“…A significant increase of luciferase activity was observed in the presence of full-length TBX1 for both the 6x TR and the 6x½SPS when compared to transfection of the empty pCDNA3.1 vector (TR: 29 fold; Students t test, *p<0.001; ½SPS: 5.6 fold; Students t-test, *p<0.02). …”

Relative difference in the peak value of the free energy barrier during R4 transition for all hydrophobic core residues mutated to alanine, compared to the value for WT. by Christine S. Schwaiger (302070)

“…<p>The standard error for the WT is the absolute standard error. A decrease or increase is defined by the cutoff 5 kJ/mol. …”

The dynamics of protein phosphorylation. by Ilan Smoly (3704866)

“…The red line depicts a 2-fold increase in the steady-state level of <i>Y</i>^<i>P</i>, achieved by 2-fold decrease in the phosphatase activity (<i>k</i> = 1, <i>p</i> = 0.5, denoted as KK and P, respectively). …”

Unusual behaviour of phototrophic picoplankton in turbid waters by Boglárka Somogyi (821047)

“…We hypothesize that this unusual behaviour of APP in turbid waters is a result of either diminished underwater light intensity or a reduced grazing pressure due to high inorganic turbidity.…”

Citral inhibition of I_TRPV1 reveals the expression of TRPV2 and TRPV3 in acutely isolated dorsal root ganglion neurons. by Stephanie C. Stotz (129157)

“…(C) Representative dorsal root ganglion currents from a neuron potentiated (2.3 fold; +100 mV) by repeated 2-aminoethyldiphenyl borate application are shown. …”

MRI exams demonstrated the homing of labeled EPCs into tumors. by Xin-Yi Wang (115163)

“…(D) Coinciding with the signal enhancement detected from T₁-weighted images, intratumoral T₁ relaxation time initially decreased to (1.60±0.06)×10³ ms at day 3 and persisted at (1.62±0.09)×10³ ms until day 5. …”

Disease progression phenotypes, clinical cohorts, and our computational framework together with the reproducibility of disease progression pattern. by Kimiyo N. Yamamoto (213724)

“…For validations of PDAC progression at the terminal stage, we utilized data of 369 patients who had all necessary information: (a) the final scan within two months before death; (b) the date of death; and (c) type and duration of CTx. …”