Data_Sheet_3_Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer A... by Gurbet Tutumlu (8691720)

“…In the first approach, a molecular docking and filtering approach is used to rank compounds based on their docking scores and only a few top-ranked molecules are selected for further long (100-ns) molecular dynamics (MD) simulations and in vitro tests. …”

Data_Sheet_2_Integrating Ligand and Target-Driven Based Virtual Screening Approaches With in vitro Human Cell Line Models and Time-Resolved Fluorescence Resonance Energy Transfer A... by Gurbet Tutumlu (8691720)

“…In the first approach, a molecular docking and filtering approach is used to rank compounds based on their docking scores and only a few top-ranked molecules are selected for further long (100-ns) molecular dynamics (MD) simulations and in vitro tests. …”

Figure 3 by Michael S. Akhras (60473)

“…<b>C</b>) DNA amounts were set at 100 ng for HPV-45 plasmid and 1 nanogram for HPV-59 plasmid, which was observed as a ∼3-fold decrease in signal intensity. …”

PAMs ameliorates the psoriasis-like symptoms and skin inflammation in imiquimod-induced mice. by Rongkun Dou (1887913)

“…<p>A: Histopathological investigation in each group (×100). …”

Regional burden, trends, and future projections of chronic kidney disease due to type 2 diabetes mellitus in South Asia: insights from the global burden of disease study (1990–2021... by Lovely Jain (21260188)

“…</p> <p>From 1990 to 2021, prevalence decreased slightly (e.g. India: 5.4% to 5.2%), while mortality increased (e.g.Pakistan: 33.7 to 42.1 per 100,000). …”

Hierarchically clustered ANIm heatmap across Set-R combined with phylogenetic information reveals unknown species diversity within the ACB clade. by Bardya Djahanschiri (6203681)

“…These clusters and cutoffs are typically used for bacterial species delineation. In the ACB clade, we observe a large and distinct cluster with 98–100% sequence identity (rounded) for the <i>A</i>. …”

Generation of transcriptome datasets. by Paul Montague (285622)

“…The resultant transcriptome database (<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0009892#pntd.0009892.s007" target="_blank">S2 Table</a>) set out for each pairing in order of decreasing p values and corresponding fold changes.</p> <p>(XLSX)</p>…”

G4-DNA Formation in the <em>HRAS</em> Promoter and Rational Design of Decoy Oligonucleotides for Cancer Therapy by Alexandro Membrino (206370)

“…When we introduced in sequence <em>hras</em>-1 or <em>hras</em>-2 two point mutations that block quadruplex formation, transcription increased 5-fold, but when we stabilized the G-quadruplexes by guanidinium phthalocyanines, transcription decreased to 20% of control. …”

Deterministic sensitivity analysis. by Katharina Wahedi (7136459)

“…Bars on the right indicate an increase of ICER, bars on the left show a decrease of ICER. Changes resulting from increasing the parameters are represented by green bars while those resulting from a decrease of parameters are shown in red.…”

Resveratrol Protects Chondrocytes from Apoptosis via Altering the Ultrastructural and Biomechanical Properties: An AFM Study by Hua Jin (320594)

“…CCK-8 assay showed that 100 μM RV significantly prevented SNP-induced cytotoxicity. …”

Table_1_Hadal Biodiversity, Habitats and Potential Chemosynthesis in the Java Trench, Eastern Indian Ocean.DOCX by Alan J. Jamieson (8706015)

“…<p>The Java Trench is the only subduction trench in the Indian Ocean that extends to the hadal zone (> 6,000 m water depth), and except for sevenbenthic trawls acquired around the 1950s, there has been little to no sampling at hadal depths undertaken since. In 2019, we undertook a 5-day expedition comprising a scientific dive using a full ocean depth-rated submersible, the DSV Limiting Factor, seven hadal-lander deployments, and high-resolution bathymetric survey. …”

Infiltration of blood clots by cancer cells. by Stephanie Rossnagl (553093)

“…(F) Evaluation of cancer cell numbers when injected 5 minutes after clot induction showed a significant decrease in the number of cancer cells detected in the bone marrow at 1 hour after clot induction (p<0.05) but not at later time points (4, 24 and 48 hours after clot induction) (p = ns). n = 4–8 per time point.…”

ScFv 2LF dissociation rate constants with each LF variant, measured by Biacore experiments. by Philippe Thullier (320909)

“…<p>The five residues whose mutation to alanine resulted in a 3-fold, or larger, decrease of the dissociation constant are shown in bold.…”

The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy by Abdelaziz, Iman Ahmed

“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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Mutation analysis of GATA and ETS sites in the −252/+38 region of the promoter. by Alexandra Le Bras (243728)

“…<p><b>A</b>. Right; H5V endothelial cells (black bars) and L929 fibroblasts (white bars) were transfected with 80 fmoles of pGL3basic (Ctrl), −8409/+38Luc or a −8409/+38Luc mutant where the GATA (GATAmt) site had been mutated, and with 54 fmoles pCH110 normalization vector. …”

Image_8_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_3_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_2_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_4_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Image_6_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”