Cardiovascular genes are dysregulated in FVB/N KLF2−/− AV region. by Aditi R. Chiplunkar (282141)

“…(<b>A–C</b>) In E10.5 FVB/N KLF2−/− AV region there is significantly decreased expression of (<b>A</b>) Tbx5 (p = 0.0175), (<b>B</b>) Gata4 (p = 0.0164) and (<b>C</b>) Sox9 (p = 0.019) mRNA compared to FVB/N WT, but Mix WT and Mix KLF2−/− hearts have no differences in expression of these genes. …”

Impact of gradually removing non-contact pairs of sites on partner inference performance. by Andonis Gerardos (12551763)

“…In panels A and C, data is generated just once. In panels B and D, each point is averaged over 100 generations of the data.…”

Metabolic changes associated with AN5568 treatment. by Pieter C. Steketee (466154)

“…Numbers at blue dots correspond to the following metabolites that were significantly decreased: 1) [PC(14:0)] 1-tetradecanoyl-sn-glycero-3-phosphocholine (m/z: 467.3014, RT: 4.75 min, 0.35-fold), 2) sn-glycerol 3-phosphate (m/z: 172.0136, RT: 16.44 min, 0.40-fold), 3) D-glucosamine 6-phosphate (m/z: 259.0457, RT: 17.68 min, 0.47-fold), 4) 2-deoxy-D-ribose 5-phosphate (m/z: 214.0242, RT: 16.45 min, 0.39-fold), 5) Asp-Asp-Cys-Pro (peptide) (m/z: 448.1256, RT: 17.64 min, 0.22-fold). …”

Limited indirect effects of an infant pneumococcal vaccination program in an aging population by Mark van der Linden (109670)

“…</p><p>Methods and findings</p><p>Reported IPD cases decreased in children under two years of age from 11.09 per 100,000 in 2003–2006 to 5.94 per 100,000 in 2017/18, while in adult age groups, reported IPD cases rose across the board, most dramatically in adults 60 years of age and over, from 1.64 to 10.08 cases per 100,000. …”

Vpu induces the degradation of human tetherin in 293T cells but stabilizes its expression in COS cells. by Abdul A. Waheed (652885)

“…One day posttransfection, cells were lysed and subjected to western blot analysis with the indicated antibodies. Vpu decreased tetherin expression by 3.1 fold in 293T cells whereas it increased tetherin expression by ∼5-fold in COS cells; levels of the delCT mutant were increased ∼3-fold in COS cells and 1.6 fold in 293T cells by Vpu. …”

Establishment of ex vivo cetuximab sensitivity assays. by Takahiro Tashiro (827031)

“…<p>A, Growth of C132 CTOSs cultured with the indicated doses of cetuximab for 7 days. …”

Nluc sensitivity and cellular detection limit in vitro, in vivo and ex vivo. by John D. Ventura (8087951)

“…GFP⁺ cells) were determined by flow cytometry and the 100 μl aliquot was then serially diluted two-fold on a 96 well plate and imaged using an IVIS Spectrum instrument after adding Nano-Glo Nluc substrate at a final ratio of 1:40. …”

Clinical improvement of juvenile macaques with chronic diarrhea following <i>T. trichiura</i> treatment. by Mara Jana Broadhurst (120227)

“…Fecal consistency scores (FCS) were based on a standardized 4-point scale; 1 = Well-formed, normal; 1.5 = Normal to semi-solid; 2 = Semi-solid to normal; 2.5 = Semi-solid; 3 = Semi-solid to liquid; 3.5 = Liquid to semi-solid; 4 = Liquid. …”

Micro-dystrophin expression levels result in reduced mdx pathology by Louise R Rodino-Klapac (36687)

“…<p><b>Copyright information:</b></p><p>Taken from "A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy"</p><p>http://www.translational-medicine.com/content/5/1/45</p><p>Journal of Translational Medicine 2007;5():45-45.…”

Gene Profiling of Postnatal <i>Mfrp^rd6</i> Mutant Eyes Reveals Differential Accumulation of <i>Prss56</i>, Visual Cycle and Phototransduction mRNAs by Ramani Soundararajan (651915)

“…In <i>Mfrp^rd6</i> eyes, a significant 1.5- to 2.0-fold decrease was observed among transcripts of genes linked to retinal degeneration, including those involved in visual cycle (<i>Rpe65</i>, <i>Lrat, Rgr</i>), phototransduction (<i>Pde6a</i>, <i>Guca1b</i>, <i>Rgs9</i>), and photoreceptor disc morphogenesis (<i>Rpgrip1</i> and <i>Fscn2</i>). …”

PDTC inhibits the <i>Nacrein</i> promoter activity. by Juan Sun (439334)

“…Increasing amounts of PDTC lead to a decrease in luciferase activity, suggesting a decrease in <i>Nacrein</i> promoter activity. …”

Challenge with P. gingivalis W83 Strain Elicits Potent Neutrophil Recruitment and Activation in the Peripheral Blood Compared to the Rbr⁻ Strain by Piotr Mydel (19843)

“…In the case of mice infected with the W83 strain, the number of neutrophils increased five-fold compared to the number of neutrophils in mice infected with the Rbr⁻ strain (gated events). …”

Although Hrq1 is needed for cisplatin resistance, it is degraded by the proteasome upon cisplatin exposure. by Thong T. Luong (13833935)

“…Wild-type (WT) or <i>hrq1Δ</i> disrupted cells were five-fold serially diluted on medium containing 30 μg/ml cisplatin and/or 0.1% DMSO, grown for 48 hours at 30°C, and photographed. …”

Genes differentially expressed in response to heat-shock-induced overexpression of , grouped according to functional classes by Ronny Leemans (54731)

“…</p><p>Copyright © 2001 Leemans et al., licensee BioMed Central Ltd</p> Bars represent the fold change between differentially expressed genes in heat-shocked wild-type embryos and heat-shocked hs- embryos. …”

RIG-I expression in neurons following JEV-infection. by Arshed Nazmi (215284)

“…Immunoblotting from whole brain lysates and their densitometric analysis showed increased (approximately 5-fold) expression of RIG-I in JEV-infected and JEV+S-MO groups. 3′MO treatment caused a significant decrease in RIG-I levels. …”

Air entrainment and pressure drop in low-cost ejectors by DANIEL D. LIMA (10365123)

“…However, when a rotameter was installed at the air line, the head losses resulted in a pronounced decrease (3-fold) in the air entrainment rate. The maximum air-water entrainment ratios reached by the low-cost ejectors was 1.7, while the pressure drop was about 80% of the upstream pressure. …”

Amino acid residues in J_H6 and RF2 of D3-3 germline gene segments are critical to binding and neutralization of HIV by long HCDR3-containing antibodies PG9 and PG16. by Bryan S. Briney (165782)

“…Residues shown to be critical to binding or neutralization of HIV, defined as ≥10-fold decrease in either binding or neutralization when mutagenized <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036750#pone.0036750-Pancera1" target="_blank">[5]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036750#pone.0036750-Pejchal2" target="_blank">[24]</a> are indicated by filled circles.…”

Effects of S1P receptor modulators on uptake of FITC-labeled dextran and PI3K activity. by Lukasz Japtok (299762)

“…Values of the densitometric analysis are expressed as x-fold decrease of p-Akt formation compared to untreated cells ± SEM from three experiments. …”

Uptake of FITC-labeled dextran by XS52 cells via macropinocytosis in a PI3K dependent manner. by Lukasz Japtok (299762)

“…Values of the densitometric analysis are expressed as x-fold decrease of phosphorylated Akt (p-Akt) formation compared to untreated cells ± SEM from three experiments. …”

Intrinsic DNA binding affinity differences for ETS1 and ELF1. by Peter C. Hollenhorst (255761)

“…The K_D of ETS1 and ELF1 for the ETS consensus sequence was 1.7×10⁻⁹ and 1.7×10⁻¹⁰ M, respectively. The fold decrease in affinity due to the A to T change, the C to A change, and the combination of both changes were 1.0, 1.5, and 2.4 for ETS1 and 3.6, 1.9, and 18.3 for ELF1, respectively.…”