Hypermethylated promoter regions are inaccessible to MspI endonuclease digestion by Marc M Oshiro (11109)

“…Inset within the graph is the average calculated fold decrease and standard deviation when MDA-MB-231 and UACC1179 cells are compared to MCF10A. …”

Nbs1 foci formation and Nbs1 expression is Myc dependent. by Lina Guerra (85942)

“…Each bar represents the mean of three independent experiments ± SD; * statistically significant decrease in Nbs1 foci formation. A cell with more than 5 nuclear foci was scored as positive. …”

A Concanavalin A screen for gene knockouts capable of restoring cell surface glycoproteins under DPAGT1 inhibition. by Hans M. Dalton (5532668)

“…Tun treatment caused a ~5-fold decrease in ConA staining intensity on average. …”

Model for a role of monomeric and fibrillar β₂-microglobulin (β₂m) cytotoxicity in dialysis related amyloidosis. by Morwenna Y. Porter (197770)

“…<p>(1) Elevated levels of circulating β₂m monomer form amyloid deposits in osteoarticular tissues. (2) Circulating monocytes are able to differentiate into both macrophages and osteoclasts. (3) Monocyte-derived macrophages infiltrate β₂m amyloid deposits, but the resistance of the amyloid fold to proteolysis in combination with β₂m amyloid cytotoxicity, prevents the clearance of the amyloid deposits. (4) β₂m amyloid induced monocyte/macrophage cell death also contributes to reduced osteoclast formation, causing a decrease in the resorption of old bone. (5) Osteoblast cell death in the presence of β₂m monomer and/or fibrils causes decreased bone formation. (6) Decreased bone resorption and formation contribute to pathological alterations to normal bone homeostasis. (7) Chondrocyte cell death in the presence of β₂m monomer and/or fibrils causes decreased cartilage formation, which could allow gradual loss of this tissue and exposure of bone to cytotoxic β₂m monomer and fibrils.…”

Data_Sheet_3_Shielding of Photosynthetic Apparatus by Consortia of Bacterial Endophytes in Tomato Plants Suffering From Fusarium Wilt.DOCX by Himani Chaturvedi (12560083)

“…The consortia of both the isolates significantly reduced the infection percentage by about 67% and a 3-fold decrease in disease severity was observed as compared to pathogen control. …”

Inhibition of fenretinide induced apoptosis by knockdown of STRA6 gene expression. by Navdha Mittal (650261)

“…Data are presented as fold change in relative mRNA expression of STRA6 in siSTRA6 transfected cells and siCTL transfected cells and represent the mean ±SEM of 5 independent experiments. …”

Genes down-regulated in 4-dpf zebrafish eleutheroembryos exposed to tBHQ for 6 hr, relative to DMSO-treated eleutheroembryos. by Mark E. Hahn (255116)

“…<p>All probes listed in this table had significant (p<0.05, ANOVA with 5% FDR correction) and >2-fold decrease in expression in tBHQ-treated relative to DMSO treated embryos. …”

Comparison of the enzymatic activities of native wt RM.TthHB27I and recombinant synthetic RM.TthHB27I thermozymes. by Daria Krefft (4518481)

“…(A) Titration of native wt RM.TthHB27I MTase activity. 0.5 μg of 1789 bp PCR DNA substrate was incubated for 6 h with decreasing amounts of native wt RM.TthHB27I in the MTase reaction buffer supplemented with 100 μM SAM and 6 mM Ca²⁺ at 65°C. …”

Mixture models. by Nedialko I. Krouchev (535037)

“…<p><b>A:</b> Red trace: Existence/creation <i>P</i> parameter-range for the 2 additional fixed points (saddle-node in the middle branch, and unstable center/focus in the top branch of the B.D.’s) With Δ<i>V</i>_1/2 = 13 mV, <i>P</i> ≥ 0.648, which is very close to the minimum relative <i>Na</i>/<i>K</i> conductivity ratio (0.663) needed for 3 FP’s in the single-<i>Na</i>_<i>v</i>-subtype model with Δ<i>V</i>_1/2 = 0 mV. …”

Effects of malaria on the proteome in mammary gland tissue of postpartum mice. by Mamoru Niikura (4103791)

“…<p>(A and B) Venn diagram of protein levels in mammary gland tissue of uninfected and infected postpartum mice that changed 0.5-fold (A) or 2-fold (B) compared with uninfected virgin mice. …”

Estimation of reproduction number is heavily dependent on the initial condition of E. by Dongju Lim (22190709)

“…The influence of bias in continues noticeably well after the time point where the initial condition was estimated, and decreases over time, leading to convergence in the estimated reproduction numbers.…”

Fluorescence intensity quantification of O4 and MBP and immunohistological assessment of oligodendrocyte markers. by Georgia Panagiotakos (76482)

“…At 6 months post radiation, a spike in O4 levels is followed by a significant decrease that persists until one year and thereafter. …”

Package of menthol measures for thirst relief: a randomized clinical study by Viviane Moreira Serato (8142273)

Altered VZV gene expression following keratinocyte differentiation. by Meleri Jones (517263)

“…Log₂ (fold changes) are shown relative to the median CPM for each gene. …”

Erratum: Why Do the Clients of Georgian Needle Exchange Programmes Inject Buprenorphine? by Otiashvili D. (4271656)

“…<i>Results:</i> Pharmaceutical buprenorphine in the form of Subutex® was the most commonly injected drug in terms of lifetime (95.5%) and last-month (75%) prevalence of use. 48% of those study participants who had injected Subutex at some point reported having used it to cope with withdrawal or to give up other opioids. 90.5% of Subutex injectors used 1–2 mg as a single dose, and the mean frequency of its injection was 6 times per month. 75% of Subutex injectors had used 3 or more types of illegal drugs during the last 30 days. …”

PSI score versus effect of IE2F depletion on TSR strength. by Ming Li (91180)

“…Repressed and activated TSRs increase and decrease in strength, respectively, when IE2F is depleted. …”

Inhibiting S6K1 does not alter pFMRP S499 levels <i>in vivo</i>. by Christopher M. Bartley (560971)

“…N = 3 per time point. (<b>B</b>) Immunoblots from cortical lysates from CD1 mice treated IP with rapamycin (Rapa, 1.5 mg/kg for 5 days), PF-4708671 (PF, 75 mg/kg for 2 hours), and vehicle (DMSO) alone. …”

Reduced willingness to participate in large events. by Alyssa H. Sinclair (17102689)

“…Change in willingness was rated on a 5-point Likert-style scale. A) Mean change in willingness by event size. …”

X-ray solution scattering analysis indicating that fragmentation is radiation dose dependent. by Timothy R. Stachowski (9652625)

“…EndoH_CYS was irradiated at pH 7.5 and the results shown are averages of two replicates at a concentration of 5.0 mg/ml. …”

Tumor microenvironment facilitates the emergence of high levels of drug resistance. by Feng Fu (218124)

“…Tumor cells can migrate to the two nearest neighbouring compartments with equal probability <i>v</i>/2. Acquisition of two point mutations is needed to survive in the center with the maximum drug concentration, <i>D</i>₀. …”