Golgi staining and Sholl analysis of pyramidal neurons in CA1. by Juan Beauquis (359752)

“…(C) Quantification of the dendritic length of CA1 pyramidal neurons for the three distance ranges studied: 20–100 µm, 120–200 µm and 220–300 µm. Significant differences were found in the 20–100 µm range with a decrease in DIAB-SC mice (* <i>p</i><0.05 vs. …”

Quantification of localization and signaling during endocytosis. by Charanya Rengarajan (511093)

“…Activation by co-transfection of Fgf8 leads to a significant 19-fold increase, and co-transfection of Hsc70 and Fgf8 decreased this activation to a 10-fold activation of double phosphorylated Erk.…”

Electrical resistance and impermeability of <i>S. lacustris</i> epithelia. by Emily D. M. Adams (236428)

“…<p>(<b>A</b>) The resistance to ion passage of <i>Spongilla</i> epithelia derived from aggregates (Ag) (1098.5 Ω cm²±671.5 s.e. n = 33) and gemmules (Gm) (1932.5 Ω cm²±253.5 s.e. n = 22) was comparable to the resistance of epithelia from vertebrate tissues (MPT =  mammal proximal tubule, MGB =  mammal gall bladder, SPT =  salamander proximal tubule, RC =  rabbit colon, MDT  =  mammal kidney distal tubule FTS =  frog/toad skin; FWG =  freshwater fish gill; TUB =  toad urinary bladder). …”

dataset.zip by Guo Bin (3537743)

“…Notably, we did not perform meta-analysis for GTCS, since there were very few studies (1 for GMV increase, 2 for GMV decrease) about this subtype. …”

Cross-sectional profile of the elevation of the ground surface and permafrost surface along two transects in the silty uplands under different disturbance regimes from 2009 to 2012 by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture by Pekka Kallunki (398041)

“…MRP2 was induced by 27 compounds followed by MDR1 (16) > BCRP (9) > OCT1 (8) > OATP1B1 (5) > MRP3 (2).</p><p>3. CYP3A4 appeared to be down-regulated (≥2-fold decrease in mRNA expression) by 53 compounds, 10 for CYP2B6, 6 for OCT1, 4 for BCRP, 2 for CYP1A2 and OATP1B1 and 1 for MDR1 and MRP2.…”

Seasonal Variation in the Skin Transcriptome of Common Bottlenose Dolphins (<i>Tursiops truncatus</i>) from the Northern Gulf of Mexico by Frances M. Van Dolah (22016)

“…In contrast, season had a profound effect on gene expression, with nearly one-third of all genes on the array differing in expression between winter and the warmer seasons (moderated T-test; p<0.01, fold-change≥1.5). Persistent organic pollutants (POPs) in blubber changed concurrently, reaching >two-fold higher concentrations in summer compared to winter, due to a seasonal decrease in blubber thickness and loss of stored lipid. …”

DataSheet_2_Incomplete Plasmodium falciparum growth inhibition following piperaquine treatment translates into increased parasite viability in the in vitro parasite reduction ratio... by Annabelle Walz (8053880)

“…In this parasite isolate, incomplete growth inhibition translated to only a 2.5-fold increase in IC₅₀ but a dramatic decrease of parasite killing in the PRR assay. …”

Increasing Elasticity through Changes in the Secondary Structure of Gelatin by Gelation in a Microsized Lipid Space by Atsushi Sakai (331283)

“…We found that gelation inside a microdroplet covered with lipid membranes increased Young’s modulus <i>E</i> toward a plateau value <i>E</i>* along with a decrease in gel size. In the case of 5.0 wt % gelatin gelled inside a microsized lipid space, the <i>E</i>* for small microgels with <i>R</i> ≤ 50 μm was 10-fold higher (35–39 kPa) than that for the bulk gel (∼3 kPa). …”

On-Chip Alternating Current Electrophoresis in Supported Lipid Bilayer Membranes by Peng Bao (399943)

“…The reduced scale of the trap structures compared to those previously used in our laboratory has led to over a 10-fold decrease in the operational time require for charge build-up, from 16 h down to 1.5 h. …”

Celastrol has an inhibitory effect on TNFα-induced NF-κB signaling in MDA-MB-231 cells. by Laura Mezzanotte (223692)

“…<p>(3.A) Graph representing the decrease in fold NF-κB induction in MDA-MB-231 cells using celastrol by the multicolor assay (* p value <0.05; ** p value <0.01). (3.B) Composite image of the unmixed spectrum of luciferases: green signals represent CBG99 emission, red signals represent PpyRE9 emission spectrum and blue signals represent ExtGluc expression in control cells (first column) and cells treated with TNFα in combination with increasing concentrations of celastrol (0.1–3 µM). (3.C) Left: graph reporting the relative band intensity of p65 protein from the nuclear extract of control sample and samples treated with TNFα (10 ng/ml) or TNFα + celastrol (0.1 µM; 0.5 µM and 1 µM). …”

The Role of <em>AtMUS81</em> in Interference-Insensitive Crossovers in A. thaliana by Luke E Berchowitz (33566)

“…Data from genetic intervals on Chromosomes 1 and 3 show that <em>Atmus81</em> mutants have a moderate decrease in meiotic recombination. Importantly, measurements of recombination in a pair of adjacent intervals on Chromosome 5 demonstrate that the remaining crossovers in <em>Atmus81</em> are interference sensitive, and that interference levels in the <em>Atmus81</em> mutant are significantly greater than those in wild type. …”

Quantification of histone acetylation level in rcd1, xlpra2, erd and xlpra1 retinas. by Tatyana Appelbaum (4015127)

“…In contrast, acetylated H3 histone shows mostly unchanged pattern, except in 16 wks xlpra2 where it was increased. * indicates significance level 5% (p<0.05).</p>…”

Mapping of mAb neutralizing activity. by Tysheena P. Charles (3385586)

“…The mAb is indicated above each graph, which displays percent infectivity plotted against mAb concentration in μg/ml. mAbs VRC01 (<b>E)</b> and EM4C04 (<b>F)</b> were used as positive and negative controls, respectively. (<b>G)</b> The log10 fold increase or decrease in IC₅₀ titer of each mutant PV relative to the parental BG505 PV is shown. …”

Effects of Fenretinide on Ishikawa cell viability and apoptosis (A–E). by Navdha Mittal (650261)

“…Data are presented as fold change in relative fluorescence units from DMSO treated samples and represent the mean ±SEM of 4–5 independent experiments. …”

Data_Sheet_1_Linkage of Marine Bacterial Polyunsaturated Fatty Acid and Long-Chain Hydrocarbon Biosynthesis.PDF by Marco N. Allemann (6547442)

“…Co-expression of pfaA-E along with oleA from Shewanella pealeana in Escherichia coli yielded the expected product, a 31:8 ketone along with a dramatic ∼10-fold reduction in EPA content. The decrease in EPA content was independent of 31:8 ketone production as co-expression of an OleA active site mutant also led to identical decreases in EPA content. …”

Fig 3 - by Nasser Semmo (76848)

“…<p>Distribution of mean FSS score at screening (Day -28), baseline (Day 1), Day 28, Day 84 and 12 weeks post-treatment (Day 168) is shown for (a) the sdITT population, (b) the mITT population and (c) all patients that had a completed FSS questionnaire for all study visits (n = 39). The decrease in mean FSS score from baseline (Day 1) to Day 28, Day 84 and 12 weeks post-treatment (Day 168) is shown for (d) the sdITT population and (e) the mITT population. ° = outlier (value maximum 1.5 to 3 fold box length); FSS = fatigue severity scale, mITT = modified intention to treat; sdITT = scaled down intention to treat; V = study visit.…”

DataSheet_1_Incomplete Plasmodium falciparum growth inhibition following piperaquine treatment translates into increased parasite viability in the in vitro parasite reduction ratio... by Annabelle Walz (8053880)

“…In this parasite isolate, incomplete growth inhibition translated to only a 2.5-fold increase in IC₅₀ but a dramatic decrease of parasite killing in the PRR assay. …”

Changes in RNA expression and protein levels with ED-deleted MARCKS. by Timothy D. Rohrbach (680245)

“…Violin plot displays > 1.5 log fold increase in GBM cells overexpressing an ΔED-MARCKS protein as compared to WT MARCKS. …”

Display of gene expression involved in hormone biosynthesis and signalling pathway. by Yun Ren (512044)

“…<p>Significantly differentially expressed genes (DEGs) (log2 fold change (FC) ≥ 1, FDR ≤ 0.05) were visualised using the Mapman software and organised into functional categories (BINs). …”