Pharmacological blockade of K_ATP channels negates the hippocampal synaptic and neuronal protection afforded by ketones. by Do Young Kim (131974)

“…There was a reversible, dose-dependent blockade by 5HD of the PS when either ketones or 100 μM DZ were applied concurrently with H₂O₂. …”

Over-expression of NF-Y or USF increases <i>Miwi</i>-luciferase activity. by Yu Hou (164094)

“…All transfection experiments were repeated at least three times and the data are shown as the fold increase or decrease over the luciferase activity of pGL3-5M4. …”

Luciferase (luc) expression in BALB/c mice injected with wild-type or 3JCLI4-targeted phage is only modestly affected by clodronate-mediated depletion of phagocytic cells by HA Lankes (36184)

“…A decrease in luc gene expression in animals treated with clodronate liposomes prior to phage or DNA injection was observed, although this decrease was not statistically significant ( > 0·05, Student's two-tailed -test). …”

Influence of galanin on shear stress-induced neurotoxicity in primary cultured cortical neurons. by Meili Liu (327309)

“…<p>A) Histograms show that pretreatment with galanin (Gal) at 1 µM, 100 nM, and 10 nM for 24 h counteracts the shear stress-induced decrease in cell viability, assessed by MTT assay at 10 dyn/cm² and 20 dyn/cm². …”

Intrinsic and extrinsic fluorescence spectroscopy of the protease 1147. by Hossein Tarrahimofrad (9016994)

“…<p>(A) Intrinsic fluorescence spectroscopy of protease 1147 in the temperature range of 40–100°C exhibited a decrease in fluorescence intensity in temperature higher than 80°C and a blue shift in 100°C. …”

Data_Sheet_1_Persulfide Dioxygenase From Acidithiobacillus caldus: Variable Roles of Cysteine Residues and Hydrogen Bond Networks of the Active Site.pdf by Patrick Rühl (5535440)

“…The protein (AcPDO) had 0.77 ± 0.1 Fe/subunit and an average specific sulfite formation activity of 111.5 U/mg protein (V_max) at 40°C and pH 7.5 with sulfur and GSH following Michaelis–Menten kinetics. …”

Data_Sheet_2_Persulfide Dioxygenase From Acidithiobacillus caldus: Variable Roles of Cysteine Residues and Hydrogen Bond Networks of the Active Site.ZIP by Patrick Rühl (5535440)

“…The protein (AcPDO) had 0.77 ± 0.1 Fe/subunit and an average specific sulfite formation activity of 111.5 U/mg protein (V_max) at 40°C and pH 7.5 with sulfur and GSH following Michaelis–Menten kinetics. …”

Alterations in Growth and Morphology of <i>Ganoderma lucidum</i> and <i>Volvariella volvaceae</i> in Response to Nanoparticle Supplementation by Swarnjeet Singh (9310473)

“…The present investigation explores the effect of <i>in vitro</i> supplementation of TiO₂, silica and silver NPs on radial growth and ultrastructural changes in the hyphae and spores of two mushroom genera, <i>Ganoderma lucidum</i> and <i>Volvariella volvaceae.</i> A concentration dependent decrease in radial growth on NP amended potato dextrose agar medium was recorded. …”

Induced expression of <i>NBPF1</i> in human tumor cells impairs colony formation in soft agar. by Karl Vandepoele (74589)

“…Only colonies larger than 100 μm were counted. Induction of NBPF1 expression by adding Dox results in a severe decrease in the number of colonies in comparison to the control setting (Mock) or the non-induced (-Dox) cells.…”

cLTP-induced DA-actin exodus is blocked by an inhibitor of myosin II ATPase. by Toshiyuki Mizui (513144)

“…<p>Neurons (21 DIV) were preincubated with 100 µM (S)-(−)-blebbistatin (aBL, the active form of blebbistatin) for 30 min and then stimulated with cLTP solution for 3 min. …”

Cortical effects of STN-DBS stimulation with the patient at rest. by Mahdi Mahmoudzadeh (572024)

“…<p><b>(A)</b> EEG was band-pass filtered [100–200 Hz] and brain stimulation artifacts were marked in order to determine brain stimulation periods based on optical data. …”

Molecular Insight into the Slipperiness of Ice by Bart Weber (5226785)

“…Measurements of the friction coefficient of steel-on-ice over a large temperature range reveal very high friction at low temperatures (−100 °C) and a steep decrease in the friction coefficient with increasing temperature. …”

3D reduced mitochondria size and complexity in the <i>Dscaml1 mutant</i> retina. by Mellisa R. Clemons (17319503)

“…(p = 0.002 and p < 0.001, respectfully). <b>E)</b> A decrease in the percent of total mitochondrial volume that mitochondria over 1.00 um³ make up in <i>Dscaml1</i> mutant retina was observed compared to wildtype and <i>Bax</i> null retinas (p = 0.043 and p = 0.031, respectfully). …”

CTR1 silencing inhibits angiogenesis. by Gomathy Narayanan (456259)

“…C. Tube formation assay: a - Control, b- Cu 100 µM, c- Cu 100 µM+si 1 - 10 nM, d- Cu 100 µM+Ssi 10 nM, e- Cu 100 µM+P 800 µM. …”

Comparison between the Uncoiling/Coiling Forces of the Fimbrial Shaft versus the Lifetime of the FimH–Mannose Bond by Manu Forero (65268)

“…The solid triangles (left axis) show the fraction of FimH–1M bonds that last longer than 1 s in flow chamber experiments (<i>n</i> = 4 to 6 for each point). These experiments are described in detail in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0040298#pbio-0040298-g005" target="_blank">Figure 5</a>. …”

AMPK activators reduce DVL3 in cervical cancer cells. by H. T. Kwan (291038)

“…(D) Upon treatment of 1.25 μM A23187, the decrease of DVL3 could be observed after 10 and 12 hours in C33A and CaSki respectively, while a further 100% reduction of DVL3 was observed at 12 and 24 hours for both cell lines. …”

Simulations of synaptic excitation and inhibition. by Stefano Masoli (9928807)

“…(B) PSTH of responses elicited by a short train (5 impulses @100 Hz) to 20 MF, 20 AA, and 89 PF synapses. …”

Topo IIβ is required for the induction of selective genes in differentiating cerebellar granule cells. by Kuniaki Sano (268855)

“…Logarithm of signal intensity ratios, (D5)/(D1) vs. (D5+)/(D5), were plotted. Data points separated by 2-fold and 0.5-fold lines are grouped as labeled. …”

Siglec-1 expressed in LPS mDCs capture distinct ganglioside containing vesicles, such as HIV-1 viral-like particles, liposomes, and exosomes. by Nuria Izquierdo-Useros (91232)

“…Of note, Siglec-14 shares 100% of amino acid homology with Siglec-5 in the V-set domain. …”

Gene Expression Profiling in the Type 1 Diabetes Rat Diaphragm by Erik van Lunteren (223425)

“…There was increased expression of genes involved in palmitoyl-CoA hydrolase activity (a component of lipid metabolism) (P = 0.037, n = 2 genes, fold change 4.2 to 27.5) and reduced expression of genes related to carbohydrate metabolism (P = 0.000061, n = 8 genes, fold change −2.0 to −8.5). …”