Marimastat reduces necroinflammatory injury following a single dose of carbon tetrachloride (CCl4) via a TNF-dependent pathway. by Vincent E. de Meijer (343377)

“…Serum ALT levels in TNF p55−/− p75−/− animals were 5-fold lower compared to wild type controls, corroborating the findings on histology and indicating decreased hepatic injury in animals lacking both TNF-receptors (F). …”

NKT-deficient Jα18 KO mice () were primed with ovalbumin and alum as in our standard protocol in Materials and methods by Lei Fang (46620)

“…(B and C) Cytokine and TL1A mRNA expression in bronchial lymph nodes (LN; B) and lung parenchyma (C) determined by real time Taqman PCR. The fold increase or decrease of mRNA in Jα18 KO mice (Jα) adoptively transferred with WT NKT cells over mice adoptively transferred with DN TNFR25-tg NKT (DN NKT) cells is plotted.…”

Image_2_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…</p>Results<p>Results showed changes in the percentage of ECM proteins associated with EVs from glaucomatous TM cells compared to non-glaucomatous TM cells (5.7% vs 13.1% respectively). Correspondingly, we found that two ECM-related cargo proteins found across all samples, fibronectin and EDIL3 were significantly less abundant in glaucomatous EVs (<0.3 fold change across all groups) compared to non-glaucomatous EVs. …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Supplementary file 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.pdf by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Combined M002 and irradiation to neuroblastoma xenografts. by Lauren A. Gillory (469462)

“…Tumor volumes were measured twice weekly and reported as fold change in tumor volume ± standard error. There was a significant decrease in tumor volume in the animals treated with combined modalities for both tumor types (<b>A</b> and <b>C</b>). …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Image_1_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…</p>Results<p>Results showed changes in the percentage of ECM proteins associated with EVs from glaucomatous TM cells compared to non-glaucomatous TM cells (5.7% vs 13.1% respectively). Correspondingly, we found that two ECM-related cargo proteins found across all samples, fibronectin and EDIL3 were significantly less abundant in glaucomatous EVs (<0.3 fold change across all groups) compared to non-glaucomatous EVs. …”

Table 1_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Oligodendrocyte ablation affects synapse formation and remodeling at P1. by Sandrine Doretto (221560)

“…(B) Quantification of synapses number on PC's bodies performed on EM specimen at P1 (4 h after treatment) revealed a 3.2 fold increase of synapse number in MBP-TK versus WT PCs (n = 20 images, P<0.05). …”

VPA and NAM treatment modulates H3K27 acetylation at the promoters of myeloid specific genes. by Marije Bartels (532852)

“…Data represent a Venn diagram comparing the number of genes identified based on a >2-fold increase or decrease in H3K27 acetylation levels compared to the control (A). …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Table 2_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.xlsx by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”

Table_1_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.xlsx by Fiona S. McDonnell (17106334)

“…</p>Results<p>Results showed changes in the percentage of ECM proteins associated with EVs from glaucomatous TM cells compared to non-glaucomatous TM cells (5.7% vs 13.1% respectively). Correspondingly, we found that two ECM-related cargo proteins found across all samples, fibronectin and EDIL3 were significantly less abundant in glaucomatous EVs (<0.3 fold change across all groups) compared to non-glaucomatous EVs. …”

DataSheet_1_National patterns of paroxetine use among US Medicare patients from 2015–2020.docx by Luke R. Cavanah (19022435)

“…</p>Results<p>Nationally, there was a steady decrease in population-corrected paroxetine prescriptions (-34.52%) and spending (-29.55%) from 2015–2020 but a consistent, five-fold state-level difference. …”

High Performance Liquid Chromatography and Metabolomics Analysis of Tannase Metabolism of Gallic Acid and Gallates in Tea Leaves by Mingli Liu (304361)

“…In this work, we measured tannase in <i>Aspergillus niger</i> fermented tea leaves and confirmed the production of fungal tannase during pu-erh tea fermentation. A decrease in catechin and theaflavin gallates and a significant increase in GA content and the relative peak areas of ethyl gallate, procyanidin A2, procyanidin B2, procyanidin B3, catechin-catechin-catechin, epiafzelechin, and epicatechin-epiafzelechin [variable importance in the projection (VIP) > 1.0, <i>p</i> < 0.05, and fold change (FC) > 1.5] were observed using high performance liquid chromatography (HPLC) and metabolomics analysis of tea leaves fermented or hydrolyzed by tannase. …”

High Performance Liquid Chromatography and Metabolomics Analysis of Tannase Metabolism of Gallic Acid and Gallates in Tea Leaves by Mingli Liu (304361)

“…In this work, we measured tannase in <i>Aspergillus niger</i> fermented tea leaves and confirmed the production of fungal tannase during pu-erh tea fermentation. A decrease in catechin and theaflavin gallates and a significant increase in GA content and the relative peak areas of ethyl gallate, procyanidin A2, procyanidin B2, procyanidin B3, catechin-catechin-catechin, epiafzelechin, and epicatechin-epiafzelechin [variable importance in the projection (VIP) > 1.0, <i>p</i> < 0.05, and fold change (FC) > 1.5] were observed using high performance liquid chromatography (HPLC) and metabolomics analysis of tea leaves fermented or hydrolyzed by tannase. …”

Transcriptional downregulation of Bcl-2 is critical to mediate PMC-A induced apoptosis. by Cagri Bodur (282762)

“…HCT116 wt cells were treated with indicated PMC-A concentrations, harvested after 24 h for total RNA extraction, cDNA synthesis and qRT-PCR analysis (B). A marginal (∼5-fold) decrease in Bcl-2 transcription was evident upon PMC-A treatment (p<0,01). …”

VEGF reduces miR-30b expression in HUVECs. by Grant A. Howe (2558611)

“…(B) Cells were serum starved overnight in MCDB 131 with 0.5% FBS and stimulated with VEGF (50 ng/ml) for 24 hours. …”

Table 3_Comparative analysis of lipid metabolism in trophoblast subpopulations in preeclampsia and in vitro hypoxia model.csv by Ivan Antipenko (22808513)

“…In vitro hypoxia modeling in BeWo b30 cells recapitulated the SCT-specific phenotype and identified a potential regulatory mechanism: a fivefold increase in PCSK9 expression (padj = 3.53e−10) and a 1.5-fold decrease in SNX17 (padj = 1.76e−04)—key regulators that limit lipoprotein receptor recycling. …”