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18241
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18242
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18243
Suppression of <i>cac</i><sup><i>TS2</i></sup> temperature-sensitive seizure-like activity by <i>para</i><sup><i>bss1</i></sup>.
Published 2016“…Compared <i>to cac</i><sup><i>TS2</i></sup> single mutants (white bar), <i>para</i><sup><i>bss1</i></sup><i>cac</i><sup><i>TS2</i></sup> double mutants (gray bar) exhibit 5 fold decrease in TS seizure-like behaviors. Quantitative data are represented as mean ± s.e.m. …”
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18244
The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data
Published 2013“…After adjusting for confounding factors, the mg/kg dose of piperaquine was found to be a significant predictor for recrudescence, the risk increasing by 13% (95% CI 5.0%–21%) for every 5 mg/kg decrease in dose; <i>p</i> = 0.002. …”
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18245
Steady state changes in leading edge activity sensors following modulator addition.
Published 2018“…Filled bars represent the fold change as the activity approaches a new steady state level approximately 5 min after modulator addition (t = 4.5 to 5.5 min (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0196678#sec012" target="_blank">Methods</a>)). …”
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18246
Table1_Early long-term low-dosage colchicine and major adverse cardiovascular events in patients with acute myocardial infarction: a systematic review and meta-analysis.docx
Published 2023“…</p>Results<p>Eight studies identified from 564 screened records were analyzed, with 5,872 patients after AMI. The length of follow-up varied from five days to 22.7 months, and 0.5–1.0 mg colchicine was administered daily. …”
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18247
TLR4 took part in HMGB1-induced activation of NF-
Published 2013“…Compared to the HMGB1 stimulation, TLR-4 neutralizing antibody pretreatment resulted in a decrease in NF-kB protein level as well as in phospho-IkBα level, while a concomitant increase in the cytosolic IkBα protein level. …”
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18248
Specificities mediating neutralization breadth and potency in the top 42 Protocol C neutralizers.
Published 2016“…Absent (-), very weak (+/-), weak (+), moderate (++), strong (+++), phenotype was attributed based on i) the median fold or average percent decrease in ID50 and ii) the fraction of viruses which neutralization ID50 was decreased <2 fold, <10 <50 fold or <20%, <40%, <60%, <80%. …”
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18249
Histamine activates both transient and persistent [Ca]<sub>i</sub> responses.
Published 2013“…The TRPC channel blocker SKF96365 (100 µM) decreases the histamine activated [Ca]<sub>i</sub> plateau but does not affect the transient increase activated by the neurotransmitter. …”
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18250
Pyrvinium inhibits Wnt signaling.
Published 2010“…(<b>D</b>) Pyrvinium stimulates CK1α activity. CK1α (100 nM) was incubated with recombinant casein (100 nM) plus or minus pyrvinium (10 nM) in a kinase reaction containing [γ<sup>32</sup>P]ATP followed by SDS-PAGE and exposure to PhosphoImager screen. …”
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18251
HDAC inhibition blocks Glyc-Alb induced activation of HDACs.
Published 2016“…<p>(A) ARPE19 cells showed a significant decrease in Ac-α-tubulin at 6 h post treatment of Glyc-alb (100 μg/mL) compared to administration of the same concentration of Alb. …”
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18252
A model of the effect of the Bar1 protease on yeast signaling.
Published 2010“…These data fit well to Hill functions with unit cooperativity but with a 5-fold difference in their EC<sub>50</sub>s. (C) Average gradient of GPCR-α complexes across the surface of the <i>MAT</i><b>a</b> cell. …”
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18253
Protein expression changes induced by CIE paradigm.
Published 2013“…The pie charts show the amount of protein that increases and decreases within three ranges: 5-15%, 16-20%, >20% (absolute values); the numbers in brackets indicate the number of protein spots in that category. …”
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18254
Mutation of LUSH<sup>D118</sup> does not affect the responses of OR67d neurons to cVA.
Published 2013“…There are no statistically significant differences in cVA sensitivity due to genotype (ANOVA, <i>p</i> = 0.1183). There is a small but significant decrease in cVA-sensitivity at 100% cVA stimulation for LUSH<sup>D118A</sup> when compared to LUSH<sup>wt</sup> (<i>p</i><0.05; Tukey's multiple comparison tests). …”
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18255
Complexity for ephaptic-off and ephaptic-on networks.
Published 2024“…Both models were simulated for N = 100. (b) Complexity for different synaptic intensity. …”
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18256
Reduction in PD-1 Expression on Epitope-Specific CD8<sup>+</sup> T Cells after Sequence Evolution in the Respective Epitopes
Published 2008“…In the graph on the left, data from the early time point are shown by the black tracing, while data for the late time point are shown by grey shading. …”
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18257
Coordinated control of ISC proliferation by the UPR<sup>ER</sup> and ROS signaling.
Published 2014“…P values from Student's T test, N>200 (from 6–7 WT, Xbp1<sup>RNAi</sup> guts), N>100 (from 3–4 WT, Hrd1<sup>RNAi</sup> guts). (B) Over-expression of spliced Xbp1in ISCs/EBs (using esg::Gal4, tubG80<sup>ts</sup>) resulted in decreased DHE fluorescence in ISCs under Paraquat treatment. …”
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18258
Chromatin relaxation affects spliceosome recruitment to nascent RNA and binding of splicing factors to ncRNAs.
Published 2012“…Each junction was analyzed separately, and for each junction genes included in the analysis (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048084#s3" target="_blank">Materials and Methods</a>) were divided into categories of increased (Up), decreased (Down) or unchanged (less than 2-fold change in any direction) U2AF65 counts in a region of +/−100 nt around the corresponding junction. …”
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18259
Real-time PCR corroboration of gene transcription profiles obtained by microarray analysis.
Published 2012“…<p>Transcription of a subset of genes analyzed by real-time PCR is depicted in the scatter plots and is displayed as fold change relative to control-injected bladders at 1, 3 and 5 weeks post-injection. …”
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18260
Effects of ABP135<sub>G1-G3</sub> on actin filament severing.
Published 2015“…<p>A total of 2 μM preformed CapG capped pyrene actin filaments was diluted to 100 nM in S2 buffer with various concentrations of ABP135<sub>G1-G3</sub>, and immediately, the decrease in pyrene fluorescence intensity that accompanied actin depolymerization was monitored for 300 s.…”