Modulation of PIP₂ levels by PLC activity in INS-1 and RyR2^KO cells. by Kyle E. Harvey (4375987)

“…<b>C)</b> Time lapsed TIRFm images of GFP-C1-PLCdelta-PH localization to the plasma membrane upon stimulation with 100 μM carbachol in a control INS-1 cell. Scale bar = 10 μm. …”

Molecular left-right patterning and GRP morphology after exposure to formin agonist IMM-01. by Natalia Petri (13774492)

“…<p>(A) Formin agonist IMM-01 reduced the proportion of left-sided <i>nodal1</i> expression at 100 μМ concentration in the embryos treated during cleavage (p-value = 0,0000007118) and during gastrulation and neurulation (p-value = 0,000002126, two-proportions z-test with Bonferroni correction). …”

PFC and CD68⁺-macrophage accumulation during early infection time course (<b>0–8 dpi</b>). by Stephanie Weibel (127241)

“…<p>(<b>A</b>) timeline - 1936-MEL melanoma-bearing athymic nude mice were i.v. injected with emulsified PFC in each case 4 days before tumors were harvested. 1×10⁷ pfu of GLV-1h68 was i.v. administered at day 0 and tumors were harvested for <i>ex vivo </i>¹⁹F MRI at 0, 2, 4, 6 and 8 dpi (2 tumors/time point). …”

MiRNA-miRNA interaction network in peripheral blood of patients with myocardial infarction: a gene expression meta-analysis by Setareh Zahedian (18175375)

“…Among identified miRNA-miRNA-mRNA networks miR-188-5p/miR-299-3p/natural killer cell granule protein (NKG7), miR-200a-3p/miR-199b-5p/granzyme B (GZMB), and miR-377-3p/miR-581/oviductal glycoprotein 1 (OVGP1) exhibited higher scors in terms of expression levels (>2-fold increase or decrease) and strengh of interactions (ΔG < −5). …”

A High Force of <i>Plasmodium vivax</i> Blood-Stage Infection Drives the Rapid Acquisition of Immunity in Papua New Guinean Children by Cristian Koepfli (191306)

“…In this cohort, <i>P. vivax</i> episodes decreased three-fold over the age range of 1–4.5 years.…”

Dietary Omega-3 Fatty Acid Supplementation Reduces Inflammation in Obese Pregnant Women: A Randomized Double-Blind Controlled Clinical Trial by Maricela Haghiac (792230)

“…</p><p>Results</p><p>The sum of plasma DHA and EPA increased by 5.8 fold and ω-3 FA/ ω-6 FA ratio was 1.5 in treated vs. untreated women (p< 0.005). …”

Human quad liver-on-chip system as a tool toward bridging the gap between animals and humans regarding toxicology and pharmacology of a cannabidiol-rich cannabis extract by Laura E. Ewing (5470541)

“…Administration of CRCE in mice resulted in nearly 4-fold elevations of plasma ALT at 615 mg/kg (<i>p</i> < 0.01) and a dose-dependent decrease in intrahepatic miR-122. …”

Table_1_HIV-1 and opiates modulate miRNA profiles in extracellular vesicles.docx by Allen Caobi (8858777)

“…Exposing SH-SY5Y to xEVs derived from HIV-infected PBMCs resulted in significant decrease in calcium signaling, relative to treatment with xEVs derived from uninfected PBMCs. …”

DataSheet_1_Spatiotemporal variation in marine litter distribution along the Bulgarian Black Sea sandy beaches: amount, composition, plastic pollution, and cleanliness evaluation.p... by Radoslava Bekova (18844189)

“…Results indicate a 48% decrease in marine litter distribution on beaches from 1462 ± 147 items/100 m in 2021 to 753 ± 97 items/100 m in 2023, with Artificial polymer materials/plastic materials constituting 88.62% of the total litter amount. …”

Brivanib inhibits liver fibrosis induced by thioacetamide. by Ikuo Nakamura (548298)

“…There was a significant decrease in the number of bands in both the 25 mg/kg and 50 mg/kg brivanib groups, compared to placebo. …”

Collagen XVI overexpression leads to an increase of ILK/kindlin-1 interaction. by Konstanze B. Bedal (513309)

“…COLXVI cell clones exhibit an increased interaction of kindlin-1 and ILK at focal adhesions compared to mock control cells (<b>A+B</b>). After inhibition of focal adhesion formation with soluble RGD peptides (c  =  100 µg/mL) ILK/kindlin-1 interaction was significantly reduced (p<0.001, n = 100) (A+<b>C</b>). …”

Image_1_Differential Functions of Two Metalloproteases, Mrmep1 and Mrmep2, in Growth, Sporulation, Cell Wall Integrity, and Virulence in the Filamentous Fungus Metarhizium robertsi... by Rong Zhou (138287)

“…Growth rates of the resulting ΔMrmep1 and ΔMrmep2 mutants decreased by 16.2 and 16.5%, respectively, relative to the wild-type (WT) strain. …”

Nef-dependent activation of IRF-3 and synthesis of IFNβ requires the integrity of the Acidic Cluster. by Giorgio Mangino (125924)

“…<p>(<b>A</b>) MDMs were treated with myr⁺ wt as well as with ΔN-Term, G2A or myr⁺ 4EA recNef (100 ng/ml for 30′). …”

Arrhenius and Eyring analysis of McLOV proteins. by Kaley K. El-Arab (733285)

“…In contrast 337-TF, has markedly increased enthalpies of activation (71 kJ/mole vs. ~50 KJ/mole) with a decrease in the entropic penalty (-44 J/mole*K vs. ~ -100 J/mole*K).…”

Voxel-level imaging comparison of lvPPA and DAT. by Ajay Madhavan (405788)

“…All images were generated using an uncorrected statistical threshold of p<0.001 and an extent threshold of 100 voxels. A decrease in brightness of the render reflects increased distance from the surface of the tissue.…”

Graph to show numbers of cells observed on the articular cartilage surface by Frances MD Henson (78253)

“…At day 11 and day 20 there was a significant decrease in the number of cells on the cartilage surface in the samples cultured in the presence of 100 ng/ml BMP-2 (*) compared to both control and SIL sections.…”

90 biotin-MNP streptavidin-response curve data by Gabrielle Moss (19742920)

“…<p dir="ltr">These data demonstrate 90 biotin-MNP 3rd harmonic phase (phi 3) as a function of streptavidin concentration (streptavidin-response curve) in 1.00x, 0.50x, 0.03x, 0.015x, 0.005x, and 0.00x PBS solutions. …”

Collagen distribution in transverse sections of femoral and tibial ACL insertions. by Jeffrey P. Spalazzi (453272)

“…High collagen content was found in the ligament and bone regions, with a gradual decrease in collagen observed within the fibrocartilage interface progressing from ligament to bone for both femoral and tibial insertions. …”

Effect of α-santalol on cell viability and proliferation. by Sreevidya Santha (381262)

“…<p>Human breast cancer cells MCF-7 and MDA-MB-231 and normal human breast epithelial cells MCF-10A were treated with either DMSO (control) or 10–100 µM α-santalol for 12, 24 and 48 h. …”

Voxel-level imaging findings in lvPPA and DAT when compared to controls. by Ajay Madhavan (405788)

“…All images were generated using an FDR corrected statistical threshold of p<0.0005 and an extent threshold of 100 voxels. A decrease in brightness of the render reflects increased distance from the surface of the tissue.…”