Impact of post-dialysis calcium level on <i>ex vivo</i> rat aortic wall calcification by Daniel Azpiazu (4385854)

“…In this regard, the dialysate calcium concentration is a modifiable tool for modulating the risk of vascular calcification. We explored pre- and post-dialysis phosphate and calcium concentrations in stable chronic haemodialysis patients treated by dialysis with the KDIGO-suggested 1.5 mmol/L calcium dialysate to investigate the effects on <i>ex vivo</i> calcification of rat aortic rings.…”

Image_1_Distinct Brain Dynamic Functional Connectivity Patterns in Schizophrenia Patients With and Without Auditory Verbal Hallucinations.JPEG by Yao Zhang (134381)

“…Dynamic functional connectivity was studied with a sliding-window method and functional connectivity states were then obtained with the k-means clustering algorithm in the three groups. We found that schizophrenia patients with AVHs were characterized by significant decreased static functional connectivity and enhanced variability of dynamic functional connectivity (non-parametric permutation test, Bonferroni correction, p < 0.05). …”

Adult RGC puromycin concentration-response curve after 7 DIV. by Yong H. Park (9739893)

“…<p>Varying treatment concentrations of puromycin (1, 10, 100, 1,000, 10,000ng/mL) decreased RGC viability in a concentration-dependent manner. …”

Photomicrographs illustrating the lesion appearing in the hilus of dentate gyrus after <i>status epilepticus</i> (SE), in pilocarpine-treated rats. by Chiara Lucchi (451435)

“…<p>The lesion was investigated using the Fluoro-Jade B staining in saline (A), ghrelin (B) and JMV-1843 (C) groups. JMV-1843 administration decreased the number of Fluoro-Jade B-positive cells (D).* = <i>P</i><0.05 vs both saline and ghrelin groups, Fisher's LSD test. …”

Hedgehog signaling (Hh) is down-regulated at the insertion in <i>ScxCre;Smo^f/−(</i>Smo tKO). by Chia-Feng Liu (365174)

“…<p>(A) Control mice (B) Smo tKO. The reduction of beta-gal staining (blue) in the Smo tKO indicated that Hh signaling was decreased in the insertion site. …”

Oxidative stress-induced Akt downregulation mediates green tea toxicity towards prostate cancer cells by Posadino, Anna Maria

“…Treatment of PC3 cells with 30 and 100μg/ml PE significantly decreased cell viability and proliferation. …”
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Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions by Harfouche, Manale

“…Pooled HSV-2 proportion in genital ulcer disease was 50.7% (95% CI: 44.7–56.8%) and in genital herpes it was 97.3% (95% CI: 84.4–100%). Interpretation: Seroprevalence is declining by 2% per year, but a third of the population is infected. …”
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Data Sheet 1_EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures.pdf by María Victoria Villar (20955281)

“…<p>Most safety cases for radioactive waste disposal consider a temperature limit of 100°C for the clay buffers. …”

Over-expression of SOCS1 blocked IFN-α and IFN-λ signaling pathway. by Bing Liu (70818)

“…<p>Over-expression of SOCS1 repressed IFN-induced ISRE-luciferase activity (A), decreased IFN-α and IFN-λ induced ISG15 and MxA (B) mRNA and protein levels (C) and STAT1 phosphorylation (C) in Con1b replicon cell. …”

Micro-scale Spatial Clustering of Cholera Risk Factors in Urban Bangladesh by Qifang Bi (2151490)

“…Strong spatial clustering of exposures at a small spatial scale in a cholera endemic population suggests a possible role for highly targeted interventions. …”

COMPARE-MS assay performance by Srinivasan Yegnasubramanian (27577)

“…The degree of capture of unmethylated DNA (untreated WBC DNA) in the presence of MBD2-MBD is less than or equal to the capture of DNA in the absence of MBD2-MBD or anti-His antibody, showing that capture of unmethylated DNA during the DNA capture step of COMPARE-MS is almost completely due to low amounts of non-specific binding to the protein G magnetic beads, as opposed to low-level binding of the MBD2-MBD to unmethylated DNA. () Plots showing the measured amount of methylated CGIs in M.SssI treated and untreated WBC genomic DNA versus the amount of input DNA after enriching for methylated DNA by the combination of methylation-sensitive restriction enzyme digestion and MBD2-MBD capture (COMPARE-MS) followed by real-time PCR. When 20–100 ng of input DNA are used, COMPARE-MS has a >5000-fold dynamic range, which is ∼500-fold higher than that of methylation-sensitive restriction enzyme used alone and ∼5- to 10-fold higher than that of MBD2-MBD capture used alone. () Plot showing measured output methylated CGIs as determined by COMPARE-MS when decreasing amounts of M.SssI-treated WBC DNA is diluted in 20 ng of untreated WBC genomic DNA. …”

Mutation-intolerant IDRs carry characteristic UniProt features compared to relatively tolerant IDRs. by Shehab S. Ahmed (12231721)

“…The horizontal dashed line at OR = 1.0 indicates no association between a residue type and a feature. To facilitate the visualization, minimum and maximum values of OR along the y-axis are set to 0.05 and 10.0, respectively. …”

The evolution of color space similarity among objects across CNN layers and the dependence of color space similarity on object form similarity. by JohnMark Taylor (8329326)

“…Results for random networks are averaged across 100 random initializations of the network. c. A schematic illustration of comparing color space similarity and object form similarity, using the same notations as those in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0253442#pone.0253442.g002" target="_blank">Fig 2A</a>. …”

Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc... by Jun Yang (2084)

“…The 75 mg and 100 mg q12h groups showed a higher proportion of AUC_ss,24h within the therapeutic window. …”

Linking neural data with behavioral data in the EVA framework. by Quynh-Anh Nguyen (847240)

“…Averaged spike counts over <i>N</i>_<i>in</i> A1-neurons, , are normal-like distributed with means <i>m</i>_<i>DF</i> and standard deviation decreasing inversely with ; shown in gray (<i>DF</i> = 3), black (<i>DF</i> = 5) and light-gray (<i>DF</i> = 7) for <i>N</i>_<i>in</i> = 10 (upper panel) and <i>N</i>_<i>in</i> = 100 (lower panel). …”

Metabolic signature of aging and longevity in serum as per LC/MS eicosanoids profiling. by Sebastiano Collino (385873)

“…<p>Reported is median value in ng/100 µl serum among the three age groups. Blue denotes negative/decreased concentration, orange denotes positive/increased correlation, black denotes no changes. …”

Table_2_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.pdf by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”

DataSheet_2_Erythropoietin mediates re-programming of endotoxin-tolerant macrophages through PI3K/AKT signaling and protects mice against secondary infection.docx by Xue Zhang (166886)

“…Therefore, our findings indicate that EPO mediates the functional re-programming of endotoxin-tolerant macrophages. Mechanistically, we found that PI3K/AKT signaling contributed to EPO-mediated re-programming through upregulation of Irak3 and Wdr5 expression. …”

Table_1_Comparative Expression Analysis of Stress-Inducible Candidate Genes in Response to Cold and Drought in Tea Plant [Camellia sinensis (L.) Kuntze].XLSX by Lidiia S. Samarina (9911892)

“…Using qRT-PCR we revealed that 10 genes were significantly upregulated in response to both cold and drought in tea plant: HSP70, GST, SUS1, DHN1, BMY5, bHLH102, GR-RBP3, ICE1, GOLS1, and GOLS3. …”

Image_8_Three-Week-Old Rabbit Ventricular Cardiomyocytes as a Novel System to Study Cardiac Excitation and EC Coupling.TIF by Anatoli Y. Kabakov (11722298)

“…Freshly isolated and 48-h-old-cultured cells expressed critical ion channel proteins: calcium voltage-gated channel subunit alpha1 C (Ca_vα1c), sodium voltage-gated channel alpha subunit 5 (Nav1.5), potassium voltage-gated channel subfamily D member 3 (Kv4.3), and subfamily A member 4 (Kv1.4), and also subfamily H member 2 (RERG. …”