Expression of 5-HT_4(b), 5-HT_2A, 5-HT_2B and 5-HTT mRNA in left ventricular myocardium. by Trond Brattelid (290970)

“…(A) 5-HT_4(b) mRNA levels decreased with foetal and neonatal development and the level in adult myocardium was one tenth of that at day -3 but reappeared in HF; (B) 5-HT_2A mRNA expression increased at birth (day 1), decreased during neonatal development and was unaltered in HF; (C) 5-HT_2B mRNA expression was transiently increased at birth (day 1) compared to adult (day 113) and not changed in HF; (D) 5-HTT mRNA expression was lower in foetal hearts compared to neonatal, adult, Sham and HF which all showed a similar expression level. …”

Theme 5 results—mortality. by Corey J. A. Bradshaw (8032406)

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Distribution of miRs with a greater than two fold-change. by Stephanie L. Samani (17896610)

A decrease in the synthesis of all viral proteins in A549 cells infected with PIV5-W3 is observed by 36h p.i. by Dan F. Young (6321425)

Mean Decrease in Margin (MDM) variable importance. by Yuliya V. Karpievitch (259460)

HC-070 decreases anxiety in a standard EPM. by Stefan Just (4811358)

Concentrations of 5-HT and 5-HIAA in brain tissue. by Thibault Renoir (348572)

“…Both 5-HT and 5-HIAA concentrations were decreased in the hippocampus (A/B), the cortex (C/D) and the striatum (E/F) in female HD mice when compared to WT animals. …”

Inducing proteotoxic stress in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. by Lisa Patricia Deliu (13570709)

Activation of vMC-dDG pathway decreases the competitive advantage of fear engram cells in the dDG neuronal network and attenuates fear generalization. by Kun Cui (2070772)

Crude and adjusted analysis of the incidence of decreased glomerular filtration over the 6-year study period, considering Model 1 and Model 2. by Camila de Souza dos Santos (17721066)

TITAN decreaser macroinvertebrate heatmap Heatmap of sensitive (i.e., <i>z-</i>) macroinvertebrate taxa (y-axis) to at least one of the five stressors, in decreasing order of numbe... by Brent J. Bellinger (21156150)

Fig 5 - by Edward M. Lawrence (3146364)

Effect of 5-HTR blockade on the relationship between error rate and reaction time in the reward-size task. by Yukiko Hori (299784)

Subjects:

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…<i>In vivo</i>, the photoactivation of dorsal raphe serotonergic neurons gave rise to a prominent light-evoked field response that displayed some sensitivity to a 5-HT1A agonist, consistent with autoreceptor inhibition of raphe neurons. …”

Nrf2 activation decreases PMN ROS production in response to zymosan. by Doumet Georges Helou (7255823)

Mitochondria extracted from frozen cortex and brainstem tissue recorded greater complex 1 activity. by Amelia Kate Pollard (3164691)

Mean <i>μ</i>_<i>i</i> and standard deviation <i>σ</i>_<i>i</i> of <i>i</i> = [0%, 1%, 2.5%, 5%] concentration datasets. by Ishriak Ahmed (14265562)

Oral UOX decreased SUA (A), BUN (B) and Cr (C) (mean ± SD, n = 10). by Yu Yun (4710340)