Collaborative approach of individual participant data of prospective studies of de-escalation in non-immunosuppressed critically ill patients with sepsis by Antonio Gutiérrez-Pizarraya (3823534)

“…<p><b>Background</b>: There is a concern to conduct de-escalation in very sick patients.…”

Image_1_Characteristics of steroid hormones in systemic lupus erythematosus revealed by GC/MS-based metabolic profiling.tif by Dehong Wu (2236318)

“…Principle component analysis demonstrated that the steroid profile was obviously distinguished between patients with SLE and controls. A lower level of total androgens was observed in patients, and nine androgens [dehydroepiandrosterone (DHEA), testosterone, Etio, androsterone, βαβ-Diol, Epi-An, Epi-DHT, 16α-OH-DHEA, and A-Diol] underwent significant decrease. …”

DataSheet1_Synthesis and biological evaluation of the novel chrysin prodrug for non-alcoholic fatty liver disease treatment.ZIP by Ruiming Zhang (3555281)

“…<p>Background: Chrysin (5,7-dihydroxyflavone) is a natural flavonoid that has been reported as a potential treatment for non-alcoholic fatty liver disease (NAFLD). …”

DataSheet2_Synthesis and biological evaluation of the novel chrysin prodrug for non-alcoholic fatty liver disease treatment.docx by Ruiming Zhang (3555281)

“…<p>Background: Chrysin (5,7-dihydroxyflavone) is a natural flavonoid that has been reported as a potential treatment for non-alcoholic fatty liver disease (NAFLD). …”

Longitudinal serum nAb mapping. by Tysheena P. Charles (3385586)

“…Red shading indicates a log fold reduction of 0.5log10 of greater; green shading indicates a log fold increase of 05.log10 or greater. …”

Table_1_Exercise-Induced Plasma Metabolomic Profiles in Patients With Peripheral Arterial Disease.pdf by Wendsèndaté Yves Semporé (11722121)

“…The best discriminant metabolites contributing to the model included a subset of 71 (47%) of the 150 accurately measured metabolites in the plasma, comprising 3 acylcarnitines, 3 amino acids, 5 biogenic amines, 9 sphingomyelin, 7 lysophosphatidylcholines, and 44 phosphatidylcholines. …”

Influenza-Like-Illness and Clinically Diagnosed Flu: Disease Burden, Costs and Quality of Life for Patients Seeking Ambulatory Care or No Professional Care at All by Joke Bilcke (262673)

“…The disease and economic burden were similar for ambulatory ILI patients, irrespective of whether they received a clinical diagnosis of flu. On average, they experienced 5–6 symptoms over a 6-day period; required 1.6 physician visits and 86–91% took medication. …”

Table_3_Iodixanol density gradients as an effective phytoplasma enrichment approach to improve genome sequencing.DOCX by Bianca Rodrigues Jardim (9905733)

“…After density gradient enrichment, potato infected with a ‘Candidatus Phytoplasma australasia’-related strain showed a ∼14-fold increase in phytoplasma HTS reads, with a ∼1.7-fold decrease in host genomic reads compared to the DNA extracted from the same sample without density gradient centrifugation enrichment. …”

Temporal Trends and Outcomes of Transcatheter versus Surgical Aortic Valve Replacement in Patients with Prior Myocardial Infarction by Ayman Elbadawi (4788270)

“…</p> <p><b>Results</b><b>:</b> Among 24,090 hospitalizations with prior MI undergoing isolated AVR, 58.5% underwent TAVR. Over the study period, there was an increase in the proportion of patients undergoing TAVR and a decrease in patients undergoing SAVR (P_trend<0.001). …”

Table_2_Iodixanol density gradients as an effective phytoplasma enrichment approach to improve genome sequencing.XLSX by Bianca Rodrigues Jardim (9905733)

“…After density gradient enrichment, potato infected with a ‘Candidatus Phytoplasma australasia’-related strain showed a ∼14-fold increase in phytoplasma HTS reads, with a ∼1.7-fold decrease in host genomic reads compared to the DNA extracted from the same sample without density gradient centrifugation enrichment. …”

Comparison of the major phyla of the gut microbiota before and after smoking cessation. by Luc Biedermann (139959)

“…Whereas the intervention group revealed a significant increase in fractions of <i>Firmicutes</i> and <i>Actinobacteria</i> and a decrease in fractions of <i>Proteobacteria</i> and <i>Bacteroidetes</i>, the microbiota of the control groups remained rather stable. …”

Cell growth, cell viability and programmed cell death following oseltamivir treatment. by Joana T. de Oliveira (718565)

“…<p>Cell growth assessed with Trypan blue (A) or with the MTS assay (B) and programmed cell death (C) were evaluated in CMA07 and CMT-U27 cells following treatment with oseltamivir phosphate (0.305 μM, 3.05 μM, 30.5 μM and 305 μM) or PBS as control. …”

Table_2_Exercise-Induced Plasma Metabolomic Profiles in Patients With Peripheral Arterial Disease.pdf by Wendsèndaté Yves Semporé (11722121)

“…The best discriminant metabolites contributing to the model included a subset of 71 (47%) of the 150 accurately measured metabolites in the plasma, comprising 3 acylcarnitines, 3 amino acids, 5 biogenic amines, 9 sphingomyelin, 7 lysophosphatidylcholines, and 44 phosphatidylcholines. …”

MuSK patient IgG4 or IgG1-3 do not induce endocytosis of MuSK. by Inga Koneczny (481353)

“…(B) Staining was scored by two individuals as described in methods, and the scores were normalised to the score at 0 hours for each condition. A slight decrease in staining was observed for cells incubated at 37°C, and pre-fixed cells also showed this reduction. …”

Supplementary Material for: Improved Control of Secondary Hyperparathyroidism in Hemodialysis Patients Switching from Oral Cinacalcet to Intravenous Etelcalcetide, Especially in No... by Xipell M. (6276968)

“…The adherent group (62%) also showed a trend to lower iPTH levels reaching statistical significance after 5 months of follow-up. …”

Data_Sheet_1_Effects of deforestation on dissolved organic carbon and nitrate in catchment stream water revealed by wavelet analysis.docx by Kerri-Leigh Robinson (14065467)

“…This study found that after deforestation, there was an immediate increase in in-stream DOC concentrations, followed by an increase in nitrate ~1 year later. Overall, the mean DOC concentration increased, and mean nitrate concentration decreased across the catchment post-deforestation. …”

Reduced Expression of miR-200 Family Members Contributes to Antiestrogen Resistance in LY2 Human Breast Cancer Cells by Tissa T. Manavalan (406097)

“…Knockdown of ZEB1 in LY2 cells recapitulated the effect of miR-200b and miR-200c overexpression resulting in inhibition of LY2 cell proliferation by TAM and fulvestrant, but not the aromatase inhibitor exemestane. Demethylating agent 5-aza-2′-deoxycytidine (5-aza-dC) in combination with histone deacetylase inhibitor trichostatin A (TSA) increased miR-200b and miR-200c in LY2 cells. …”

Phosphinimino-amino Magnesium Complexes: Synthesis and Catalysis of Heteroselective ROP of <i>rac</i>-Lactide by Hongyan Xie (264700)

“…Complexes <b>1</b>–<b>8</b> are phosphinimino-amine-ligated THF-solvated mono­(alkyl)­s, among which <b>1</b>–<b>4</b> adopt twisted tetrahedral geometries, whereas <b>5</b> contains a trigonal bipyramido geometry core. …”

RNA Microarray Analysis in Prenatal Mouse Cochlea Reveals Novel IGF-I Target Genes: Implication of MEF2 and FOXM1 Transcription Factors by Hortensia Sanchez-Calderon (186893)

“…By contrast, there was an increase in the nuclear accumulation of FoxM1 and a corresponding decrease in the nuclear cyclin-dependent kinase inhibitor p27^Kip1.…”

Nature of the Entire Range of Rare Earth Metal-Based Cationic Catalysts for Highly Active and Syndioselective Styrene Polymerization by Fei Lin (156666)

“…The activity increased with the decrease in the rare earth metal size, in striking contrast to the literature that has shown that a large metal facilitates a high activity, which was also not a result of an enthalpic effect (Δ<i>H</i>^⧧) or an entropic effect (Δ<i>S</i>^⧧) according to Eyring plots. …”