Image6_The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice.JPEG by Vladimir M. Pogorelov (133492)

“…Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT2AR) limit their clinical use in diverse settings. …”

Glia-targeted 5-HT_2A receptor expression in adults reopens experience-dependent synaptic glomeruli pruning. by Vanessa Kay Miller (19775496)

“…There is a significant decrease in the Or42a OSN innervation volume with glial-targeted <i>Gal80</i>^<i>ts</i><i>-5-HT</i>_<i>2A</i><i>R</i> OE at 28°C (<i>n</i> = 20/condition, <i>p</i> = 1.00 × 10⁻¹⁵). …”

Data_Sheet_1_WAY-100635 Alleviates Corneal Lesions Through 5-HT1A Receptor-ROS-Autophagy Axis in Dry Eye.docx by Xujiao Zhou (6661499)

“…Western blot analysis was used to measure the expression levels of autophagic proteins microtubule-associated protein 1 light chain 3 (LC3B-I/II) and autophagy-related gene 5 (ATG5).</p><p>Results: 5-HT_1A receptor agonist (8-OH-DPAT) increased corneal fluorescein sodium staining spots and 5-HT_1A receptor antagonist (WAY-100635) decreased them. …”

Dose- and time-dependent effect of IFN-γ and TNF-α on benzamil-sensitive <i>I</i>_sc and TEER in HBECs. by Anusree Sasidharan (19226521)

Retinoic acid alleviates decreases of phospho-Akt and phospho-Bad expression caused by MCAO damage. by Ju-Bin Kang (16021324)

“…Molecular weight (kDa) are depicted at right. Data (<i>n</i> = 5) are represented as mean ± S.E.M. *<i>p</i> < 0.001, **<i>p</i> < 0.01 vs. vehicle + sham animals, #<i>p</i> < 0.01 vs. vehicle + MCAO animals.…”

<i>Ubr5</i>^<i>mt</i> synovium exhibits markers of increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

Silencing of RCC1L isoforms alter the levels of mitochondrial ribosomal proteins and biogenesis factors resulting in decreased mitochondrial translation. by Aurelio Reyes (412135)

Descriptives of the study sample, N = 451. by Orrin D. Ware (14829115)

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

<i>Kpna1</i> KO mice show decreased anxiety-like behavior in the elevated plus maze. by Koki Sakurai (11690201)

HoxA9-ER directly represses <i>Cebpa</i> gene expression in myeloid cells. by Lei Peng (260321)

Subjects:

Prenatal alcohol exposure (PAE) decreases brain and body weights at E14 and P0. by Danielle Sambo (6077924)

Graphs showing the mean temperature increase at the positions with the highest mean temperature increase for the MIPS (A) and MONO (B) systems and three drilling protocols (DP1, DP... by Marsel Ganeyev (21453399)

Fraction of time, the overall of the studied data trends durations follow a geometric distribution with parameter <i>p</i> = 0.5, and with any <i>p</i>, both cases for a significan... by Héctor Raúl Olivares-Sánchez (13014866)

Table_1_Gender-Specific Effect of 5-HT and 5-HIAA on Threshold Level of Behavioral Symptoms and Sex-Bias in Prevalence of Autism Spectrum Disorder.DOCX by Barnali Chakraborti (3410288)

“…<p>Platelet hyperserotonemia in a subset of Autism Spectrum Disorder (ASD) probands, efficacy of selective serotonin reuptake inhibitors (SSRIs) in reducing behavioral deficits and gender-bias in normal serotonin (5-hydroxy tryptamine or 5-HT) synthesis suggest disruption in stringent regulation of serotonin metabolism in ASD. …”

TPI demalonylation at K56 decreases PPP flux in CDCP1+ CSCs and is indispensable for postchemotherapeutic recurrence. by WenChao Gao (7321640)

RNF5 depletion suppresses PEL xenograft tumor growth and decreases the levels of cell cycle gene expression and hedgehog signaling in tumors. by Xiaojuan Li (351842)

Pairwise correlations of excitatory neurons in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Graphs of marginal mean values of the studied parameters for dolphin kick, flutter kick and breaststroke kick with and without diving gear (Parameters that were not statistically d... by Marek Rejman (9199616)

Figure 5 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma by Jessica D. Daley (22128489)