5-HT treatment modulates TGFβ3 mediated gene expression. by Philip R. Buskohl (146307)

“…<p><b>A</b>) TGFβ3 mRNA transcripts increase with physiological 5-HT (470 nM, <i>5-HT</i>), but decrease at high dose (47 µM, <i>5-HT+</i>). αSMA, RhoA, and col1α2, were not affected by physiological 5-HT dose, but were significantly downregulated with high 5-HT treatment. …”

Downstream molecular effects of knockdown of the expression of 5-HT_1B and 5-HT_1D receptors, on invasion and proliferation biomarkers in PaCa cells. by Nilgun Gurbuz (623605)

“…<p>(<b>A–B</b>) The effect of siRNAs-mediated 5-HT_1B and 5-HT_1D receptors down-regulation on β1 integrin/ECM-mediated downstream signaling in PANC-1 (A) and MIAPaCa-2 cells (B). …”

Myoendothelial and/or endothelial gap junctions participate to the calcium and contractile responses to 5-HT. by Marie Billaud (261506)

“…<p>Typical traces of simultaneous recordings of intracellular calcium (top panel) and contraction (bottom panel) induced by 5­HT 10 µM are shown in A. 300 µM ^37-43Gap 27 was introduced into the bath where indicated. …”

vOPG147 is associated with MITA. by Xue-Mei Yi (18851202)

(A) Activation maps contrasting the control group with the 5-HT- group showing a significant effect for aversive prediction error signals (PE) in the orbitofrontal cortex (left) an... by Catherine Hindi Attar (303972)

“…(B) Peak voxel parameter estimates show decreased aversive PE signals for the 5-HT depleted group (TRP-) compared to the control group (TRP+). …”

DataSheet_1_PACAP–PAC1 Signaling Regulates Serotonin 2A Receptor Internalization.pdf by Atsuko Hayata-Takano (525514)

“…In addition, the levels of endogenous 5-HT_2A were decreased on the cell surface of primary cultured cortical neurons after PACAP stimulation and were increased in frontal cortex cell membranes of Pacap^−/− mice. …”

Table_1_Trait sensitivity to negative feedback in rats is associated with increased expression of serotonin 5-HT2A receptors in the ventral hippocampus.DOCX by Paulina Surowka (14590340)

“…The results demonstrated that trait sensitivity to negative feedback is associated with increased mRNA expression of the 5-HT2A receptors in the rat ventral hippocampus (vHipp). …”

Presentation_1_Constitutive Serotonin Tone Modulates Molecular and Behavioral Response to Chronic Fluoxetine Treatment: A Study on Genetic Rat Model.pdf by Maja Kesić (8620716)

“…Platelet 5HT levels, a recognized indicator of SSRI efficacy, were decreased by fluoxetine treatment in both 5HT-sublines. …”

Rapid degeneration of 5-HT neurons in SERT-Cre^cre/wt Munc18-1^lox/lox mice. by Jacobus J. Dudok (338648)

“…(O) Analysis of the number of 5-HT cell bodies in the sections showed that there is no difference at E16, but at E18 and P2 there is a decrease of 80% to 90% in the number of 5-HT cell bodies in SERT-Cre^cre/wt Munc18-1^lox/lox sections. …”

In vivo assessment of 5-HT_1A and 5-HT₂ post-synaptic receptor function using 8-OH-DPAT-induced change of corticosterone levels and DOI-induced head-twitches. by Thibault Renoir (348572)

“…<p>Compared to paired-saline injected animals, administration of the 5-HT_1A agonist 8-OH-DPAT (0.3 mg/kg, s.c.) significantly increased corticosterone levels in both (A) male and (B) female mice, regardless of the genotype. …”

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

Fx controls the TNF-enhanced Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by U-87 MG cells and neuromediators availability. by Glaucia Vilar-Pereira (686134)

TG mice hearts show decreased ISO response. by Mayilvahanan Shanmugam (691549)

Positional cloning of <i>qNN1</i> on chromosome 16. by Xinxin Li (281237)

Change in levels of 5HT and its related substances in the brain of queen associated with early colony establishment. by Hitoshi Aonuma (50438)

“…B: Change in level of 5HT in the brain of queen associated with early colony establishment. 5HT significantly decreased after queen started establishing a colony. …”

Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

“…D) Effects of H-1152 and Y-27632 on the phase 1 and phase 2 TEER decreases induced by TNF. Starting at T₀, HDMEC plated on ECIS 96-well arrays received a 1 hour pre-treatment with vehicle (top panel, n = 4, 4) or with a ROCK inhibitor, either H-1152 (at 1 or 10 μM, middle panel, n = 6, 6) or Y-27632 (at 1 or 10 μM, bottom panel, n = 6, 6). …”

Incubation in Normal Saline (NS) or Plasma-Lyte (PL) rendered acidic leads to decreased endothelial dependent relaxation in intact naïve porcine saphenous veins (PSV). by Joyce Cheung-Flynn (344249)

Summary of the effect of maternal immune activation on serotonin and dopamine. by Pei-Tan Hsueh (752475)

“…The cerebral 5-HT levels were significantly decreased at 5 and 8 weeks old (solid arrow), whereas the DA levels exhibited a trend towards a decrease (dotted arrow). …”

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

Subjects: