Variability in performance and response to task dynamics. by Daniel Ramandi (10047543)

“…(E) When focusing on five consecutive successful trials, WT mice showed a significant reduction in trajectory variability, whereas zQ175 mice exhibited only a slight decrease, predominantly in the last trial, hinting at genotype-specific differences in optimizing performance following success (RM two-way ANOVA, genotype p = 0.746 F(1, 22) = 0.1074, trial p = 0.012 F(2.836, 62.38) = 4.045, interaction p = 0.018 F(3, 66) = 3.561). …”

Supplementary Materials - Antitumor activity of new chemical compounds in triple negative mammary adenocarcinoma models by Maria V Giolito (8499600)

“…According to the need for the development of new anticancer agents, we have synthetized novel bioactive compounds and aimed to determine their antitumor action. …”

The evolution of persister function, with less extreme differences in persister and nonpersister survival and growth, and differences in efficiency of resource use. by Andy Gardner (92711)

“…We assume: <i>p</i>₀ = 1, <i>T</i> = 5, <i>g</i> = 0, <i>a</i> = 1 and a range of <i>z</i>₀. …”

Combined intervention of swimming plus metformin ameliorates the insulin resistance and impaired lipid metabolism in murine gestational diabetes mellitus by Liping Huang (315281)

“…Swimming or metformin intervention slightly or moderately improves hyperglycemia, insulin sensitivity and lipid metabolism both in liver and skeletal muscle from GDM mice, while combined therapy of swimming plus metformin markedly ameliorated hyperglycemia (FPG, decreased by 22.2–59.5% from G10 to G18 versus DC group), insulin sensitivity (2.1 and 2.8 fold increase, respectively, in AKT activity versus DC group) and <i>de novo</i> lipogenesis (3.2 and 7.0 fold decrease, respectively, in ACC activity, and 1.94 and 5.1 fold decrease, respectively, in SREBP2 level, versus DC group) both in liver and skeletal muscle from GDM mice. …”

Table1_Mitral valve aneurysms: echocardiographic characteristics, formation mechanisms, and patient outcomes.xlsx by Yi Wang (32470)

“…</p>Conclusions<p>We recommend using echocardiography as a highly sensitive method for MVA diagnosis. …”

Fetal and Childhood Exposure to Phthalate Diesters and Cognitive Function in Children Up to 12 Years of Age: Taiwanese Maternal and Infant Cohort Study by Han-Bin Huang (322180)

“…A total of 110, 79, 76, and 73 children were followed up at ages 2, 5, 8, and 11, respectively. …”

Comparison of the fraction of positive relations for different behavioral updating. by Xiaochen He (455300)

“…<p>The simulation is carried out 10 times on a random network consisting of 100 nodes with average network connectivity 〈<i>k</i>〉 = 4. …”

Ingestive behavior, ruminal and blood kinetics in lambs fed cow cheese whey by Luciana Freitas GUEDES (10406055)

“…The inclusion of CCW in the diet did not impair ruminal pH, but promoted a decrease in rumination and feeding times, also causing a lower number of cuds and a lower number of cud chews. …”

Data Sheet 1_Investigating the molecular mechanisms associated with ulcerative colitis through the application of single-cell combined spatial transcriptome sequencing.docx by Hua Huang (190195)

“…Immunohistochemical analysis of UC lesion samples revealed diminished expression levels of GNG5 and elevated expression levels of TIMP1. A dextran sulfate sodium (DSS)-induced colitis mouse model was developed, demonstrating that the protein expression levels of GNG5 in the colonic tissue of model mice were significantly decreased compared to controls w)ile the expression levels of TIMP1 were increased (p < 0.01). …”

Desiccated <i>Aedes</i> eggs remodel their proteome towards lipid metabolism and TCA cycle. by Anjana Prasad (17277090)

“…Note: β-oxidation and the upper arm of the TCA cycle increase in desiccated eggs, while the PPP, glycolysis, and the lower arm of the TCA cycle decrease. Also see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002342#pbio.3002342.s002" target="_blank">S2A Fig</a> for gene ontology-based analysis and grouping of proteins that change during desiccation. …”

Annual distribution of IG-ralated AE reports. by Shaozhi Liu (13720340)

“…In pregnant women, hypoglycaemia (IC025 = 4.25) was detected as a strong signal, hypoglycaemia neonatal (IC025 = 2.96) as a medium signal, while ketoacidosis (IC025 = 0.76), decreased insulin requirement (IC025 = 0.24), and underweight (IC025 = 0.09) were identified as weak signals. …”

Proportion of AEs by SOCs in pregnant women. by Shaozhi Liu (13720340)

“…In pregnant women, hypoglycaemia (IC025 = 4.25) was detected as a strong signal, hypoglycaemia neonatal (IC025 = 2.96) as a medium signal, while ketoacidosis (IC025 = 0.76), decreased insulin requirement (IC025 = 0.24), and underweight (IC025 = 0.09) were identified as weak signals. …”

Clinical consequences of weight loss during stem cell transplantation. by Christina T. Rieger (838986)

“…<p>A: No difference in overall survival between patients that lose ≥ 5% of BMI during SCT B: Similar result for a BMI decrease of ≥ 10%. …”

Data_Sheet_1_Ecological Predictors and Functional Implications of Eye Size in Deep-Sea Shrimps.zip by Lorian E. Schweikert (3624572)

“…Our findings also suggest that the DVM imposes visual demands distinct from the average depths occupied by a species. While DVM distance correlated with relative eye size, mean depth correlated with absolute eye size, revealing that eye size increases with depth before 1,000 m, then decreases in bathypelagic (aphotic) zone. …”

Comparison of diet, age, and insulin signaling effects on CHCs. by Tatyana Y. Fedina (114609)

“…<p>Arrows indicate an increase or decrease in the relative abundance of individual CHCs: 1) for aging - from young to old age on balanced diets <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049799#pone.0049799-Kuo1" target="_blank">[18]</a>, 2) for protein – based on change from S5Y5 to S5Y20, and for sugar – based on change from S5Y5 to S20Y5, 3) for insulin signaling (IIS) - change in transgenic flies with increased insulin signaling (via insulin receptor overexpression - InR^OX) or decreased insulin signaling (insulin substrate mutants <i>chico</i>) compared to controls <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049799#pone.0049799-Kuo2" target="_blank">[19]</a>. …”

Evolution of hnRNPA1 IDR. by Simon M. Lichtinger (11326846)

“…<p><b>(A)</b> Typical GA progression for hnRNPA1. The fitness function [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009328#pcbi.1009328.e005" target="_blank">Eq (2)</a>] was evaluated at , and increases by ∼20% over 20 rounds, while maintaining population diversity. …”

Movie S1 - Quantifying Exocytosis by Combination of Membrane Capacitance Measurements and Total Internal Reflection Fluorescence Microscopy in Chromaffin Cells by Ute Becherer (74949)

“…This cell was stimulated for 2 s by depolarizing pulses and is shown 4 s prior to and 8.5 s after stimulation. Secretion of vesicles seen as a sharp decrease of fluorescence of individual spots (highlighted by white arrows) occurs simultaneously to the increase in membrane capacitance and only during the stimulation period (marked in red). …”

Modulatory effects of dopamine shown as changes in state space (interpreted after 30)(see also text). by Nico J. M. van Beveren (51667)

“…<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0002577#pone-0002577-g005" target="_blank">Figure 5</a>, top: increasing levels of dopamine augment the signal-to-noise ratio: the basin of the attractor associated with the most salient signal increases while the basins of attraction of the other attractors decrease. …”

Image_2_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…Kv7.4 channels co-expressed with wild-type (WT) CaM show inhibited activation when intracellular calcium levels increase, while Kv7.4 channels co-expressed with CaM₁₂₃₄ or CaM₃ are insensitive to calcium. Mutations C156A, C157A, C158V, R159, and R161A, which are located within the Kv7.4 S2–S3 loop, dramatically facilitate activation of Kv7.4 channels co-expressed with WT CaM but have no effect on activation of Kv7.4 channels co-expressed with CaM₃, indicating that these five mutations decrease the inhibitory effect of Ca²⁺/CaM. …”

Image_7_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…Kv7.4 channels co-expressed with wild-type (WT) CaM show inhibited activation when intracellular calcium levels increase, while Kv7.4 channels co-expressed with CaM₁₂₃₄ or CaM₃ are insensitive to calcium. Mutations C156A, C157A, C158V, R159, and R161A, which are located within the Kv7.4 S2–S3 loop, dramatically facilitate activation of Kv7.4 channels co-expressed with WT CaM but have no effect on activation of Kv7.4 channels co-expressed with CaM₃, indicating that these five mutations decrease the inhibitory effect of Ca²⁺/CaM. …”