Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

Discovery of β‑Arrestin Biased Ligands of 5‑HT₇R by Youngjae Kim (1463614)

“…In order to identify 5-HT₇R ligands with biased agonism, we designed and synthesized a series of tetrahydroazepine derivatives <b>1</b> and <b>2</b> with arylpyrazolo moiety or arylisoxazolo moiety. …”

<i>Tnks</i> DKO leads to decreased Wnt/β-catenin signaling activity. by Pan Ye (2902336)

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain by Jiawen Lang (4288540)

Subjects:

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain by Jiawen Lang (4288540)

Subjects:

Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain by Jiawen Lang (4288540)

Subjects:

Expression of cerebral serotonin related to anxiety-like behaviors in C57BL/6 offspring induced by repeated subcutaneous prenatal exposure to low-dose lipopolysaccharide by Pei-Tan Hsueh (752475)

“…We concluded that maternal immune activation induced by exposure to a low dose of LPS decreased cerebral 5-HT levels in parallel to the down-regulation of the tph2 and slc6a4 genes and in conjunction with anxiety-like behaviors in offspring.…”

5.HT_1A binding difference between known cause of death (KCOD) controls and SIDS. by Hannah C. Kinney (10280975)

“…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT_1A receptor binding. …”

Reduced callose synthesis in <i>pat</i> is associated with the decreased <i>CalS5</i> expression. by Shuang-Xi Xiong (8844044)

Cardamonin decreased the content of free fatty acids and the activity of CPT-1. by Peiguang Niu (17044532)

Cocaine CPP represses MBII-52 and 5HT2CR expression in NAc. by Hongjie Chen (590575)

“…(n = 8, **P<0.01). Decreased expression of MBII-52 (C) and not 5HT2CR (D) mRNA in the NAc after cocaine-induce CPP. n = 8 and *P<0.05.…”

Transcriptional regulation of MBII-52 and 5HT2CR by chronic cocaine in NAc. by Hongjie Chen (590575)

“…<p>Repeated cocaine administration, but not acute, significantly decreased MBII-52 (A) and not 5HT2CR (B) mRNA in NAc 24 h after the final drug injection compared with saline treatments (n = 6 mice per group; *p<0.05).…”

Cardamonin decreased the protein level of Raptor and suppressed lipogenesis and CPT-1. by Peiguang Niu (17044532)

siRNA-mediated APP-BP1 knock-down significantly decreases BrdU-incorporated fetal neural stem cells. by Yuyoung Joo (236048)

HVR1-swap compensatory E1/E2 substitutions typically decrease virus entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

ABCC3 overexpression decreases the retention of anti-cancer agents. by Sai A. Balaji (1452556)

Multi-way sensitivity analysis on transmission rate, CD4 count at diagnosis, and ART costs in a model-based analysis of Immediate ART initiation in Côte d’Ivoire. by Eric N. Ouattara (6890174)

Tumor volume decreases with increasing <i>Salmonella</i> dosage. by Robert A. Kazmierczak (3140379)

Effect of decreased endogenous betaglycan expression on metanephric development and glomerulogenesis. by Kenneth A. Walker (280683)

Image_1_Artesunate Alleviates Paclitaxel-Induced Neuropathic Pain in Mice by Decreasing Metabotropic Glutamate Receptor 5 Activity and Neuroinflammation in Primary Sensory Neurons.... by Yize Li (471459)

“…We demonstrated artesunate prevented PINP in a dose-dependent manner, while exerting a clear anti-hyperalgesic effect on already existing PINP. …”