Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”

PV1-treated mice exhibited a decrease in overall activation of T lymphocytes. by Pedro Henrique Papotto (791904)

AGE-modification of laminin leads to a decrease in Kir4.1 function. by Kayla Thompson (4885036)

PB + PER exposure decreased SYP staining in the hippocampi and cerebral cortices of exposed mice. by Zuchra Zakirova (431614)

Radiation induces an increase in splenic regulatory T cells with a decrease in T cell proliferation. by Yu Zhou (89766)

Decrease of Paneth cells in mice fed a high-fat diet (HFD). by June-Chul Lee (2850536)

Decrease of goblet cells in mice fed a high-fat diet (HFD). by June-Chul Lee (2850536)

Effects of KSS on SKF-induced decrease in endogenous ALLO content in the frontal cortex. by Qing-Yun Guo (2007082)

S5 Fig - by Xinyue Yang (629144)

Bioavailable Soil Phosphorus Decreases with Increasing Elevation in a Subarctic Tundra Landscape by Andrea G. Vincent (543626)

“…We hypothesized that the concentration of labile P fractions would decrease with increasing elevation (and thus declining temperature), but would be lower in meadow than in heath, given that N to P ratios in meadow foliage are higher. …”

Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism by Qing-Yun Guo (2007082)

“…However, the mechanisms by which GABAergic system dysfunctions induce the pathophysiology of ASD remain unclear. We previously demonstrated that a selective type I 5α-reductase inhibitor SKF105111 (SKF) induced ASD-like behaviors, such as impaired sociability-related performance and repetitive grooming behaviors, in male mice. …”

Adenylate cyclase activation does not cause translocation of PKC Apl II in response to 5HT in Sf9 cells. by Carole A. Farah (336422)

“…<p><b>A)</b> Sf9 cells were cotransfected with mRFP-PKC Apl II along with either eGFP-5HT_4Apl (n = 17), eGFP-5HT_7Apl (n = 15) or eGFP-5HT_2Apl (n = 9). …”

A low dose of BTZ decreases proteasome activity with no effect on cell viability. by A. L. Furfaro (2587792)

Data_Sheet_1_Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity.d... by Chantal C. Clark (10684632)

Mutation of <i>talB</i> in BAI3 results in a decrease of virulence partially complemented by the induction of <i>OsERF#123</i>. by Tuan T. Tran (5335004)

Adolescent intermittent ethanol (AIE) decreases choline acetyltransferase (ChAT)+IR cholinergic neurons in the adult male and female basal forebrain throughout adolescence. by Ryan P. Vetreno (663148)

CD47 expression is decreased in hematopoietic progenitor cells in patients with myelofibrosis by A. Nonino (6072632)

Table_1_v2_A long waiting time from diagnosis to treatment decreases the survival of non-small cell lung cancer patients with stage IA1: A retrospective study.docx by Bin Liu (5899)

“…After adjusting for other confounders, the waiting time was identified as an independent prognostic factor.</p>Conclusions<p>A long waiting time before treatment may decrease the survival of stage IA1 NSCLC patients. …”

Nivalenol (NIV) decreases chondrocyte viability in a dose and duration-dependent manner. by Siyuan Li (178640)

CaA decreases the CSCs-like properties of malignant HaCaT cells. by Ye Yang (297214)