Figure 1 from Histone Deacetylase Inhibitors Target DNA Replication Regulators and Replication Stress in Ewing Sarcoma Cells by Stacia L. Koppenhafer (16616290)

“…<p>HDAC inhibitors decrease RRM1, RRM2, CHK1, and WEE1 protein levels. …”

Notch and Wnt signaling-mediated activation of Müller cells in S334ter rats <i>in vivo</i>. by Carolina Beltrame Del Debbio (243080)

“…Q-PCR analysis of gene expression revealed increase in levels of transcripts corresponding to <i>Ki67</i>, <i>cyclinD1</i>, <i>Hes1</i>, <i>Hes5</i> and decrease in <i>p27^kip1</i> transcript levels in Jag1+Wnt2b treated retina, compared to controls (<b>H</b>). …”

Gene expression analysis of <i>Pten</i> mutant prostates. by Isabel B. Lokody (755298)

“…<p>(A) i) Heatmap demonstrating that control samples (C1-C5) show similar expression patterns to each other, as do mutant samples (M1-M5). ii) Genes chosen for validation are indicated in heatmap derived from the average of control and mutant samples. …”

Summary of phenotypic data of the candidate genes implicated in HR-DSBR. by Mikołaj Słabicki (246635)

“…Genes that after knockdown decreased the frequency of HR below z-score −4, −2, or −1.5 are marked with ↓↓↓, ↓↓ or ↓, respectively; genes that increase the frequency of HR over z-score 4, 2, or 1.5 are marked with ↑↑↑, ↑↑, or ↑, respectively; n.a., not available. …”

Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

Summary of case incidence (Exposed and Infected dog cases) per 10,000 dogs across 1000 simulations assuming increasing incursion probability and vaccination coverage values. by Kristyna Rysava (3213036)

“…<p>Summaries organized as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011187#pcbi.1011187.g005" target="_blank">Fig 5</a>. …”

Phosphorylation of PKA targets is greatest when PKA is colocalized with cAMP production either in the spine or in the dendrite. by Myungsook Kim (2166613)

“…(A2) Bar graph shows mean and s.e.m. of phospho-inhibitor-1 (n = 5 for each condition). …”

IL-1β depletion and IL-1 receptor antagonist treatment alleviated the neutrophilic inflammation. by Wen-Cheng Chao (2817868)

“…<p>The characteristic pulmonary histopathological images (A) of <i>M</i>. <i>marinum</i>-infected <i>Ncf1</i>^<i>-/-</i> mice and WT mice on day-5 with and without IL-1β depletion by a monoclonal antibody directed against IL-1β (150μg on day-1). …”

Cytoproliferative effect of low dose alpha radiation in human lung cancer cells is associated with connexin 43, caveolin-1, and survivin pathway by Vasumathy Rajan (6920285)

The importance of dog population contact network structures in rabies transmission by Mirjam Laager (3712447)

“…The probability of a minor outbreak also decreased with increasing vaccination coverage, but reached zero only when coverage was near total. …”

DataSheet1_Nonlinear Reactor Design Optimization With Embedded Microkinetic Model Information.pdf by Kanishka Ghosh (13109679)

“…We assemble a library of six candidate ROK models based on literature and MK model structure. …”

Comparison of the global phylogenomic characteristics of the commensal and BSI collections. by Judit Burgaya (16734180)

“…We selected the STs present in at least 5 strains in at least one of the two collections. …”

Table 1_CAMDA 2023: Finding patterns in urban microbiomes.csv by Haydeé Contreras-Peruyero (20320404)

“…We then implemented supervised models conducting 5-fold cross-validation (CV) with a 4:1 training-to-validation ratio. …”

Image 1_CAMDA 2023: Finding patterns in urban microbiomes.tiff by Haydeé Contreras-Peruyero (20320404)

“…We then implemented supervised models conducting 5-fold cross-validation (CV) with a 4:1 training-to-validation ratio. …”

Data_Sheet_1_Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain.docx by Zhongli Yang (9750611)

“…An eQTL was revealed to significantly affect EGLN2 expression in the European sample and two mQTLs were respectively detected in CpG sites in NRXN1 and CYP2A7. Interestingly, we found for the first time that the minor allele of the single nucleotide polymorphism (SNP) rs3745277 located in CYP2A7P1 (downstream of CYP2B6) significantly decreased methylation at the CpG site for CYP2A7 (cg25427638; P = 5.31 × 10^–7), reduced expression of CYP2B6 (P = 0.03), and lowered the percentage of smokers (8.8% vs. 42.3%; Odds Ratio (OR) = 0.14, 95% Confidence Interval (CI): 0.02–0.62; P = 4.47 × 10^–3) in a dominant way for the same cohort sample. …”

Image_1_Central Treatment of Ketone Body in Rainbow Trout Alters Liver Metabolism Without Apparently Altering the Regulation of Food Intake.pdf by Sara Comesaña (5689613)

“…Using rainbow trout (Oncorhynchus mykiss) as a model, we intracerebroventricularly (ICV) administered 1 μl 100 g^–1 body mass of saline solution alone (control) or containing 0.5 μmol of BHB. …”

Presentation_1_Investigation of the genetic effect of 56 tobacco-smoking susceptibility genes on DNA methylation and RNA expression in human brain.PPTX by Zhongli Yang (9750611)

“…An eQTL was revealed to significantly affect EGLN2 expression in the European sample and two mQTLs were respectively detected in CpG sites in NRXN1 and CYP2A7. Interestingly, we found for the first time that the minor allele of the single nucleotide polymorphism (SNP) rs3745277 located in CYP2A7P1 (downstream of CYP2B6) significantly decreased methylation at the CpG site for CYP2A7 (cg25427638; P = 5.31 × 10^–7), reduced expression of CYP2B6 (P = 0.03), and lowered the percentage of smokers (8.8% vs. 42.3%; Odds Ratio (OR) = 0.14, 95% Confidence Interval (CI): 0.02–0.62; P = 4.47 × 10^–3) in a dominant way for the same cohort sample. …”

NOTCH1 Gain of Function in Germ Cells Causes Failure of Spermatogenesis in Male Mice by Zaohua Huang (439674)

“…Spermatogenesis in these mutants was progressively affected with age, resulting in decreased testis weight and sperm count. Analysis of downstream target genes of NOTCH1 signaling showed an increased expression of <i>Hes5</i>, with a reduction of the spermatogonial differentiation marker, <i>Neurog3</i> expression in the mutant testis. …”

Supplementary Material for: Association between Ambient Temperature and Risk of Ischaemic Stroke: An Observational Cohort Study by figshare admin karger (2628495)

“…The association was observed within 5 days before stroke onset for LAA but after a longer period for CE. …”

Quantification of LECs <i>in vivo</i>. by Pier-Anne Lachance (463900)

“…<p>(<b>A</b>-<b>C</b>) Single cell suspension was isolated from non-treated wild type mice, 3, or 7 days post CHS (N>5). …”