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Cost-effectiveness and budget impact of immediate antiretroviral therapy initiation for treatment of HIV infection in Côte d’Ivoire: A model-based analysis
Published 2019“…Outcomes from the model included life expectancy, 10-year medical resource use, incremental cost-effectiveness ratios (ICERs) in $/year of life saved (YLS), and 5-year budget impact. We simulated people with HIV (PWH) in care (mean CD4: 259/<i>μ</i>L, SD 198/<i>μ</i>L) and transmitted cases. …”
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GSK343 treatment decreased <i>in vivo</i> tumor volume and growth.
Published 2021“…(A) Animals treated with GSK343 had significantly decreased fold change in tumor volumes compared to mice treated with vehicle. …”
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DnaK’s ATPase activity is stimulated by ribosomes and required to reduce protein synthesis.
Published 2024Subjects: -
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DnaK does not refold heat-denatured luciferase when incubated in the presence of ribosomes.
Published 2024Subjects: -
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Estimated mean values for light interception.
Published 2024“…Empirical models for the relationships between the investigated plant traits and PD/DVP were created using linear regression analysis preceded by a lack-of-fit test. An increase in PD led to a linear decrease in inflorescence yield per plant (<i>p</i> = 0.02), whereas a positive linear relationship was found for inflorescence yield (<i>p</i> = 0.0001) and CBD yield (<i>p</i> = 0.0002) per m<sup>2</sup>. …”
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Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines.
Published 2021Subjects: -
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