SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue by Dorota Kmiec (5646374)

“…Here, we show that the Nef protein of the highly divergent SIVcol lineage infecting mantled guerezas (<i>Colobus guereza</i>) is a potent antagonist of SERINC5, although it lacks the CD4, CD3 and CD28 down-modulation activities exerted by other primate lentiviral Nefs. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Macrofaunal crustacean abundance at time series stations over the 2010–2019 period in DBO regions 2–5 regions. by Sue E. Moore (2932644)

Effects of intracellular treatment with 5- or 40-nm AuNPs on AP properties in hippocampal CA1 neurons. by Seungmoon Jung (534987)

“…<p>(A) AuNPs of both sizes significantly decreased the latency to the first AP. …”

The complex III turnover is decreased in Myc-ON mice (n = 5) compared with the Myc-OFF (n = 5) or single transgenic mice (Single Tg) (n = 4). by Hyoung-gon Lee (73934)

VEGFa, VEGFR1 and VEGFR2 mRNA levels following A2E incubation and/or light exposure. by Mélanie Marie (7535228)

Results of peptide toxicity of each diet. by Fatima Dikhanbayeva (11501962)

“…<p>Values are given as mean ± SD for a total of 50 animals. Control group (I) - 0.295 nm, Curd mass (II)– 0.122 nm, Curd mass with flaxseed flour (III)– 0.113 nm, curd mass with celery root powder (IV) - 0.114 nm, Curd mass with bee bread (V)– 0.127 nm. …”

TPI demalonylation at K56 decreases PPP flux in CDCP1+ CSCs and is indispensable for postchemotherapeutic recurrence. by WenChao Gao (7321640)

Examining the Desirable Properties of ZnSnO_<i>y</i> by Annealing Treatment with a Real-Time Observation of Resistivity by Aitkazy Kaisha (7853474)

Fig 5 - by Amanda C. Hahn (17241106)

Three-, bi- and mono-functional Vγ9Vδ2 T-cell subsets decrease in HIV+ patients. by Rita Casetti (608635)

Progesterone decreased Henkel 100-induced responses in a dose-dependent manner in the OE of female mice. by Ninthujah Kanageswaran (683924)

“…<p>(A) Representative submerged EOG esponses to Henkel 100 (1:5,000) were recorded from the surface of the septum from female mouse OE. …”

Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis by Santiago Avila-Rios (3160959)

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Theoretical Study on Reaction Scheme of Silver(I) Containing 5-Substituted Uracils Bridge Formation by Toru Matsui (1313913)

“…We present a reaction scheme of silver containing 5-substituted uracils (<b>N</b>) bridge formation with two silver ions to a silver-mediated base pair [<b>N</b>-Ag₂-<b>N</b>] by using the conductor-like polarizable continuum model (CPCM)-B3LYP/aug-cc-pVDZ level of theory. …”

Prenatal alcohol exposure (PAE) decreases brain and body weights at E14 and P0. by Danielle Sambo (6077924)

Evolution of the adjusted geometric mean plasma values of homocysteine from baseline through the 4.7 years of follow-up (with adjustment for sex, baseline plasma creatinine, type o... by Leopold K. Fezeu (5309333)

V2 vasopressin receptor abundance. by Sophie Constantin Lütken (689916)

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Reformation of oxygen gradient in a disturbed sediment. by Xuegang Mao (599968)

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Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction. by Haruka Mori (8082215)

“…<p>(A–F) the neural activity of the RID changes during the transition periods from backward to forward locomotion (A–C) and from forward to backward locomotion (D–F) in the mock (A: p = 1.5 × 10⁻⁵; D: p = 5.5 × 10⁻¹³), 5-HT exposed (B: p = 0.092; E: p = 0.79), and <i>mod-1</i> mutant (C: p = 0.081; F: p = 0.93) groups. …”