Differentially Expressed Plasma MicroRNAs and the Potential Regulatory Function of Let-7b in Chronic Thromboembolic Pulmonary Hypertension by Lijuan Guo (404771)

“…The results showed that 1) thirty five microRNAs were differentially expressed in CTEPH patients, among which, a signature of 17 microRNAs, which was shown to be related to the disease pathogenesis by <i>in silico</i> analysis, gave diagnostic efficacy of both sensitivity and specificity >0.9. 2) Let-7b, one of the down-regulated anti-oncogenic microRNAs in the signature, was validated to decrease to about 0.25 fold in CTEPH patients. 3) ET-1 and TGFBR1 were direct targets of let-7b. …”

<i>T</i>. <i>gondii</i> myosin H is associated with three myosin light chains. by Arnault Graindorge (84051)

“…<p>(A) Endogenously tagged myosin light chains (MLC) 3, 5 and 7 localized to the conoid. …”

Modulation of performance during learning. by Daniel Ramandi (10047543)

“…(B) A longitudinal comparison of the average exponential fit weight between WT and zQ175 mice reveals that while WT mice show a decreasing trend, indicating a shift towards longer duration (“timed”) trials, zQ175 mice maintain a consistently high exponential weight, demonstrating no significant change over time (b; RM two-way ANOVA, genotype p = 0.0106 F(1, 22) = 7.795, days p < 0.0001 F(5.262, 115.4) = 7.616, interaction p < 0.0001 F(57, 1250) = 2.834). …”

DataSheet_10_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.x... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_6_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_4_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_9_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_7_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_1_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_3_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_8_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.xl... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

DataSheet_2_Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems.pd... by Martina Schuster (18440214)

“…Moreover, we identified four miRNAs (miR-323a-3p, miR-382-5p, miR-370-3p, miR-134-5p) located within the DLK1-DIO3 domain, a cancer-associated genomic region, suggesting a possible importance of this region in glioblastoma progression. …”

Kinetics of differential gene expression after rapid degradation of endogenous OGT in MEFs. by Sara Formichetti (20536052)

“…Differentially expressed genes with p-value < 10⁻⁵ and absolute log₂FC > 0.3 (i.e. 1.2-fold increase or decrease in expression) are labeled in red and their number is indicated. …”

Data_Sheet_1_Evaluation of the Effect of Local Water Chemistry on Trace Metal Accumulation in Puget Sound Shellfish Shows That Concentration Varies With Species, Size, and Location... by Eileen H. Bates (10227719)

“…Carr Inlet at 20 m depth had the smallest shellfish and the highest metal concentrations. While we could not eliminate possible confounding factors, we also found higher metal concentrations in shellfish associated with lower pH, lower temperature, and lower dissolved oxygen (conditions seen at Carr Inlet at 20 m and to a lesser extent at Point Wells at 5 m depth). …”

Respiration and respiratory quotient (RQ) changes over lifespan. by Alicia M. Celotto (203614)

“…On days 5, 10 and 15 <i>ATP6¹</i> animals have a modest but significantly higher respiration rate than wildtype animals; however, by day 20 <i>ATP6¹</i> mutants show a significant decrease in respiration rate. …”

High-Throughput Profiling of <i>Caenorhabditis elegans</i> Starvation-Responsive microRNAs by Laura Garcia-Segura (824200)

“…In nature, animals often face feast or famine conditions. We observed that subjecting early L4 larvae from <i>Caenorhabditis elegans</i> to a 12-hr starvation period produced worms that are thinner and shorter than well-fed animals, with a decreased lipid accumulation, diminished progeny, reduced gonad size, and an increased lifespan. …”

Table_1_Identification and Quantification of Bioactive Molecules Inhibiting Pro-inflammatory Cytokine Production in Spent Coffee Grounds Using Metabolomics Analyses.docx by Khanh-Van Ho (7403516)

“…<p>In this study, we assessed the anti-inflammatory properties of spent coffee grounds. …”

sNAG treatment reduces bacterial infection in an Akt1 dependent manner. by Haley Buff Lindner (352313)

“…Infected wounds that were treated with peptide show a significant decrease (p<.05) in CFU. Scale bars = 50 µm. …”

The cold plantar assay can measure L4 spinal nerve ligation induced allodynia. by Daniel S. Brenner (318503)

“…<p>Mice underwent the spinal nerve ligation (SNL) procedure or a sham procedure on day 0. A. On days 3, 6, and 10 post surgery SNL mice had significantly lower cold plantar withdrawal latencies on the 1/4″ glass than sham mice (2-way ANOVA main effect ***p<0.001 with Bonferroni post-hoc test; 3d ***p<0.001, 6d **p<0.01, 10d **p<0.01; Sham n = 5, SNL n = 6). …”

Data_Sheet_1_Dietary Nitrate Supplementation Does Not Alter Exercise Efficiency at High Altitude – Further Results From the Xtreme Alps Study.docx by Philip J. Hennis (12158271)

“…Using a double-blind protocol, participants were randomized to consume a beetroot/fruit juice beverage (three doses per day) with high levels of nitrate (∼0.18 mmol/kg/day) or a nitrate-depleted placebo (∼11.5 μmoles/kg/day) control drink, from 3 days prior to the exercise trials until completion. …”