Synthesis and Evaluation of Fluorine-Substituted Phenyl Acetate Derivatives as Ultra-Short Recovery Sedative/Hypnotic Agents by Heng Zhang (320479)

“…To test this hypothesis, we developed a series of fluorine-containing phenyl acetate derivatives.…”

ChIP-seq findings identify RAREs near genes required for NMP function. by Marie Berenguer (8856509)

“…(B) Shown are RA-regulated ChIP-seq peaks for H3K27me3 and H3K27ac near <i>Fgf8</i>. In the 5′-noncoding region of <i>Fgf8</i>, we found 2 RAREs on either end of the peak for H3K27me3 (repressive mark) that is decreased in KO, indicating they are candidate RARE silencers; the RARE furthest upstream in the 5′-noncoding region at −4.1 kb was shown by knockout studies to function as an RA-dependent RARE silencer required for caudal <i>Fgf8</i> repression and somitogenesis [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000719#pbio.3000719.ref007" target="_blank">7</a>]. …”

Analysis of cytokine levels in supernatants of lymph nodes showed an altered profile in C57BL/6 APRIL-Tg mice with AIA. by Adriana Carvalho-Santos (814114)

“…Data are expressed by mean ± SEM, n = 5 and, the statistical significance was determined using One-Way ANOVA followed by Newman<i>-</i>Keuls tests.…”

Data_Sheet_1_The Clinical Trial Outcomes of Med-Zenith PT-Valve in the Treatment of Patients With Severe Pulmonary Regurgitation.docx by Xiaoke Shang (3589976)

“…Post-procedural pulmonary artery diastolic pressure increased from 5.8 ± 3.1 to 11.3 ± 2.5 mmHg. In the 3-month and 1-year follow-up, the right ventricular end diastolic volume index reduced from the baseline 181.6 ± 29.0 to 143.7 ± 29.7 ml/m² and 123.4 ± 31.2 ml/m², and the trans-pulmonary valve gradient decreased from 25.6 ± 22.2 to 10.64 ± 3.54 mmHg and 11.16 ± 3.0 mmHg, respectively. …”

Image_2_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…Moreover, the ratio of Chl a and Per showed a relative decrease of Per with increasing PAR intensity. …”

Image_1_Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont.jpeg by Holger Kühnhold (6499133)

“…Moreover, the ratio of Chl a and Per showed a relative decrease of Per with increasing PAR intensity. …”

The Antiviral Restriction Factors IFITM1, 2 and 3 Do Not Inhibit Infection of Human Papillomavirus, Cytomegalovirus and Adenovirus by Cody J. Warren (563898)

“…Here, we demonstrate that IFN-α or -β treatment of keratinocytes substantially decreases human papillomavirus 16 (HPV16) infection while robustly inducing IFITM1, 2 and 3 expression. …”

Table_1_Incidence, Progression, and Patterns of Multimorbidity in Community-Dwelling Middle-Aged Men and Women.docx by Xianwen Shang (311546)

“…The time to develop a subsequent condition decreased with the accumulation of conditions (P < 0.0001). …”

Table_1_Enhanced Prefrontal Neuronal Activity and Social Dominance Behavior in Postnatal Forebrain Excitatory Neuron-Specific Cyfip2 Knock-Out Mice.DOCX by Yinhua Zhang (111234)

“…We found that in the medial prefrontal cortex (mPFC) of adult Cyfip2 cKO mice, CYFIP2 expression was decreased in both layer 2/3 (L2/3) and layer 5 (L5) neurons, unlike the L5-specific CYFIP2 reduction observed in adult Cyfip2^+/− mice. …”

Data_Sheet_1_Comprehensive survey of transposon mPing insertion sites and transcriptome analysis for identifying candidate genes controlling high protein content of rice.DOCX by Yuki Monden (12259496)

“…We detected two rice lines harboring a significantly higher protein content (namely, HP5-7 and HP7-5) in the EG4 population. …”

Table_1_Comprehensive survey of transposon mPing insertion sites and transcriptome analysis for identifying candidate genes controlling high protein content of rice.XLSX by Yuki Monden (12259496)

“…We detected two rice lines harboring a significantly higher protein content (namely, HP5-7 and HP7-5) in the EG4 population. …”

Multiplexed Digital mRNA Profiling of the Inflammatory Response in the West Nile Swiss Webster Mouse Model by José Peña (95514)

“…This study was undertaken to evaluate the nCounter, a high throughput digital gene expression system, as a means to better understand West Nile virus (WNV) dissemination and the inflammatory response against WNV in the outbred Swiss Webster (SW) mouse model over the course of infection.…”

Complexity for ephaptic-off and ephaptic-on networks. by Gabriel Moreno Cunha (20390408)

“…<p>(a) Complexity for different neuron quantities, with <i>rp</i> = 0.1 and <i>ω</i>^(<i>k</i>) = 5 (ephaptic-off network, in blue; ephaptic-on network, in red). …”

Data_Sheet_1_Mitochondrial Deficits With Neural and Social Damage in Early-Stage Alzheimer’s Disease Model Mice.docx by Afzal Misrani (10258750)

“…We observed increased levels of mitochondrial fission protein, Drp1, and decreased levels of ATP synthase subunit, ATP5A, leading to abnormal mitochondrial morphology, increased oxidative stress, glial activation, apoptosis, and altered neuronal morphology as early as 4∼5 months of age in APP/PS1 mice. …”

Evolution in the profile of thyroid cancer cases treated in an oncology reference service: what changed in the last 20 years by Renan Bezerra Lira (7032854)

“…Neck dissection associated with thyroidectomy was done in 158 patients (19.5%). We observed a predominance of tumors classified as T1 in 602 (74.6%) patients. …”

Phosphorylated IκBα Predicts Poor Prognosis in Activated B-Cell Lymphoma and Its Inhibition with Thymoquinone Induces Apoptosis via ROS Release by Azhar R. Hussain (154380)

“…Additionally, TQ treatment also caused up-regulation of death receptor 5 (DR5), however, up-regulation of DR5 did not play a role in TQ-induced apoptosis. …”

Data_Sheet_1_Talent Selection Strategies and Relationship With Success in European Basketball National Team Programs.PDF by Anton Kalén (5038625)

“…On average, 15.6 ± 2.0 male and 12.4 ± 1.8 female players were selected per generation. Over a third of the NTs consistently selected a higher or lower number of players than the average, with a difference of 8.1 players (95% CI [5.8, 10.8]) for men and 7.6 players (95% CI [5.4, 10.0]) for women between the countries with the highest and lowest average. …”

γ-Synuclein Antibodies Have Neuroprotective Potential on Neuroretinal Cells via Proteins of the Mitochondrial Apoptosis Pathway by Corina Wilding (529868)

“…We found a protective effect of γ-synuclein antibody resulting in an increased viability (up to 15%) and decreased reactive oxygen species levels (up to −12%) of glutamate and oxidative stressed RGC-5. …”

Nucleo-Cytoplasmic Localization Domains Regulate Krüppel-Like Factor 6 (KLF6) Protein Stability and Tumor Suppressor Function by Estefanía Rodríguez (242231)

“…</p><h3>Methodology/Principal Findings</h3><p>In this study, we demonstrate using EGFP fusion constructs that KLF6/KLF6-SV1 nucleo-cytoplasmic transport is not regulated by the 5′ basic region but activated by a novel NLS encoded within the ZF domain, and a nuclear export signal (NES) located in the first 16 amino acids of the shared N-terminus sequence. …”

The Tree GSPF Level Tree Chronogram of Poison Frogs with Known Taxonomic Diversity (i.e., Numbers within Parentheses) and Significant Diversification Rate Changes for Nodes or Line... by Juan C Santos (267336)

“…The significant increases indicated by a star next to nodes 2 and 9 might be dependent on deeper nodes (i.e., 1 and 5, respectively) and produced by a “trickle-down effect” (see “Lineage Diversification” in Results).…”