Data_Sheet_1_Gene Variation at Immunomodulatory and Cell Adhesion Molecules Loci Impacts Primary Sjögren's Syndrome.docx by Sergi Casadó-Llombart (5090171)

“…All this, together with the reported association of functionally relevant single nucleotide polymorphisms (SNPs) of CD5, CD6, and CD166/ALCAM with the risk or prognosis of some immune-mediated inflammatory disorders, led us to investigate similar associations in a local cohort of patients with pSS. …”

Absence of Engrailed 1 leads to a partial dorsalization of the forelimb. by Rosa-Eva Huettl (113537)

“…<p><b>(a)</b><i>In situ</i> hybridization against <i>Lmx1b</i>, <i>Npn-2</i>, <i>Ebf-2</i>, and <i>ephrinA5</i> on E10.5 coronal sections shows that the dorsally localized genes <i>Lmx1b</i> and <i>Npn-2</i> extend their expression domain in <i>En1</i>^<i>-/-</i> mutant mice into ventral areas (arrows), whereas <i>Ebf-2</i> and <i>ephrinA5</i>, that are usually restricted to the ventral limb mesenchyme in wildtype embryos, show a diminished expression profile (arrows). …”

The <i>Runx1</i>-androgen receptor pathway. by Hitomi Ono Minagi (4417003)

Proposed functions of TDRD6 in primary spermatocyte spliceosome assembly. by Müge Akpınar (3815143)

“…TDRD6 and PRMT5 interact (iii). In TDRD6 deficient primary spermatocytes, no ChB type I form, PRMT5 association with SmB is impaired, (iv) and symmetrical dimethylation of SmB is decreased by 75% (v). …”

An important role of podoplanin in hair follicle growth by Sun-Young Yoon (338361)

“…Furthermore, HF keratinocytes isolated from K5-Cre;PDPN^flox/flox mice exhibited a decreased ability to interact with collagen type I in cell adhesion assays. …”

<i>INMAP</i> Overexpression Inhibits Cell Proliferation, Induces Genomic Instability and Functions through p53/p21 Pathways by Yan Zhu (112437)

“…In this system caused micronuclei (MNi) formation, chromosome distortion and <i>γH2AX</i> expression upregulation, suggesting DNA damage induction and genomic stability impairment. As a tumour biochemical marker, lactate dehydrogenase (LDH) isoenzymes were detected to evaluate cell metabolic activity, the results confirming that total activity of LDH, as well as that of its LDH5 isoform, is significantly decreased in <i>INMAP</i>-overexpressing HeLa cells. …”

Fig 1 - by B. Ulfhake (6293984)

Flow-stretching of quantum dot-labeled bacteriophage lambda DNA. by Fatema Tuz Zohra (11378812)

Genotypes used in each figure. by Sarah Krupp (17041601)

“…<div><p>Accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43) is seen in both neurons and glia in a range of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). …”

<i>Drosophila</i> Strains <i>used</i>. by Sarah Krupp (17041601)

“…<div><p>Accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43) is seen in both neurons and glia in a range of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). …”

DNA damage/repair pathways. by Sarah Krupp (17041601)

“…<div><p>Accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43) is seen in both neurons and glia in a range of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). …”

Nucleocytoplasmic transport pathway. by Sarah Krupp (17041601)

“…<div><p>Accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43) is seen in both neurons and glia in a range of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). …”

Inflammatory response pathways. by Sarah Krupp (17041601)

“…<div><p>Accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43) is seen in both neurons and glia in a range of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). …”

Chromatin organization pathway. by Sarah Krupp (17041601)

“…<div><p>Accumulation of cytoplasmic inclusions of TAR-DNA binding protein 43 (TDP-43) is seen in both neurons and glia in a range of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Alzheimer’s disease (AD). …”

Age-Dependent Prevalence of Nasopharyngeal Carriage of <i>Streptococcus pneumoniae</i> before Conjugate Vaccine Introduction: A Prediction Model Based on a Meta-Analysis by Olivier Le Polain de Waroux (101472)

“…In all studies nasopharyngeal carriage decreased with increasing age. We found a strong positive linear association between the carriage prevalence in pre-school childen (<5 y) and both that in school aged children (5–17 y olds) and in adults. …”

Age and Walking Speed Effects on the Complexity Index. by Hyun Gu Kang (3091131)

Δ18 reduces translation efficiency. by Bertram Brenig (317353)

“…<p>(A) Schematic diagram showing the luciferase plasmids used for translation efficiency analysis. …”

Control of Metal Ion Size-Based Selectivity through Chelate Ring Geometry. Metal Ion Complexing Properties of 2,2′-Biimidazole by David Buist (2293633)

“…The structure of <b>1</b> gave: Triclinic, <i>P</i>1̅, <i>a =</i> 8.314(2) Å, <i>b =</i> 8.677(2) Å, <i>c =</i> 14.181(3) (Å), α = 91.143(3)°, β = 104.066(2)°, γ = 106.044(3)°, <i>V</i> = 949.5(4) ų, <i>Z</i> = 1, <i>R</i> = 0.030. …”

Control of Metal Ion Size-Based Selectivity through Chelate Ring Geometry. Metal Ion Complexing Properties of 2,2′-Biimidazole by David Buist (2293633)

“…The structure of <b>1</b> gave: Triclinic, <i>P</i>1̅, <i>a =</i> 8.314(2) Å, <i>b =</i> 8.677(2) Å, <i>c =</i> 14.181(3) (Å), α = 91.143(3)°, β = 104.066(2)°, γ = 106.044(3)°, <i>V</i> = 949.5(4) ų, <i>Z</i> = 1, <i>R</i> = 0.030. …”

Genes exhibiting differential expression between metastasising and non-metastasising MCTs. by Kelly Bowlt Blacklock (6102878)