Microarray analysis of endoxifen concentration-dependent changes in gene expression in the presence of estrogen and physiologically relevant levels tamoxifen and its metabolites. by John R. Hawse (227611)

“…<p> (<b>A</b>) Venn diagram of genes whose expression levels were significantly altered by 1.5 fold or greater in MCF7 cells treated with 10 nM estrogen (E₂), 300 nM tamoxifen (TAM), 7 nM 4-hydroxy-tamoxifen (4HT) and 700 nM N-desmethyl-tamoxifen (NDT), plus indicated concentrations of endoxifen, relative to cells treated with all compounds minus endoxifen for 24 hours. …”

Short-term time-restricted feeding during the resting phase is sufficient to induce leptin resistance that contributes to development of obesity and metabolic disorders in mice by Katsutaka Oishi (278169)

Turnover of 4MUG substrate reads out GBA1 activity in human brain lysates in the presence of sodium taurocholate. by Zdenek Berger (440685)

“…When converted to specific activity, similar values are obtained when using 10–60 μg of human cortex lysates, as expected. A representative experiment is shown. C) Turnover of 4MUG substrate in lysates from human cortex is mostly due to GBA1 activity when using sodium taurocholate (NaTc). 1 mM CBE and 1 μM isofagomine (Iso) decrease the signal by ~ 90% in the presence of sodium taurocholate whereas substantially smaller reduction (~ 30%) is seen without sodium taurocholate in the assay buffer. 10 μg of protein lysate was used. …”

Effects of tones associated with drilling activities on bowhead whale calling rates by Susanna B. Blackwell (698998)

“…Increasing call repetition rates can be a viable strategy for combating decreased detectability of signals arising from moderate increases in background noise. …”

CK1δ Kinase Activity Is Modulated by Chk1-Mediated Phosphorylation by Joachim Bischof (189845)

“…Taken together, these data point towards a possible regulatory relationship between Chk1 and CK1δ.…”

Ten oxazolone challenges provoke tactile sensitivity that persists for 21 days after cessation of challenges. by Jasmine Landry (3716113)

“…Raw withdrawal thresholds at baseline and post Ox-challenge cessation for each animal are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0169672#pone.0169672.s001" target="_blank">S1 Fig</a> and summarized in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0169672#pone.0169672.s004" target="_blank">S1 Table</a>.…”

Analysis of gene expression during neurite outgrowth and regeneration-0 by Moriah L Szpara (67982)

“…</p><p>Published online 23 Nov 2007</p><p>PMCID:PMC2245955.</p><p></p>e points of DRG outgrowth (2, 5, 12, 24, and 40 hours) and 6 time points of SCG outgrowth (same as DRG plus 65 hour endpoint), for the 712 probe sets found to change more than 1.5 fold (p ≤ 0.05) in both datasets. …”

Trends and Demographic Disparities in Diabetes Hospital Admissions: Analyses of Serial Cross-Sectional National and State Data, 2008–2017 by Sara D. Turbow (12224290)

“…The analysis of individual states showed that diabetes-specific admissions in individuals ≥65 years old declined during this time (16.3-48.8% decrease) but increased among patients 18-29 years old (10.5-81.5% increase) and that rural diabetes-specific admissions decreased in just over half of the included states (15.2-69.2% decrease). …”

Aluminum toxicity reduces the nutritional efficiency of macronutrients and micronutrients in sugarcane seedlings by Carolina Eggers Borges (10398678)

Gene expression analysis and total iron concentration in <i>CYB561</i> knockdown PC-3 cells. by Romie Angelo G. Azur (18547651)

“…<p><b>(A-B)</b> Validation of <i>CYB561</i> knockdown in PC-3 cells showed that <b>(A)</b> <i>CYB561</i> mRNA expression was reduced by 74.23% at the mRNA level which was <b>(B)</b> reflected at the level of protein expression in PC-3 cells transduced with sh<i>CYB561</i> compared to the scrambled (scr) shRNA control. …”

Genetic Variants of Wnt Transcription Factor <em>TCF-4</em> (<em>TCF7L2</em>) Putative Promoter Region Are Associated with Small Intestinal Crohn's Disease by Maureen J. Koslowski (181279)

“…TCF-4 (also named TCF7L2), a Wnt signalling pathway transcription factor, orchestrates Paneth cell differentiation, directly regulates the expression of HD-5 and -6, and was previously associated with the decrease of these antimicrobial peptides in a subset of ileal CD. …”

Table_2_MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis.DOC by Yakun Chen (4794774)

“…Manipulating GGT activity and GSH homeostasis by transgenic over-expressing or RNAi MdGGT1 increased or decreased MdMIR156a5 and MdMIR156a12 levels, respectively. …”

Table_1_MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis.DOC by Yakun Chen (4794774)

“…Manipulating GGT activity and GSH homeostasis by transgenic over-expressing or RNAi MdGGT1 increased or decreased MdMIR156a5 and MdMIR156a12 levels, respectively. …”

HGR increases equilibrium fitness. by C. Scott Wylie (145239)

“…See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1001108#pgen.1001108.s005" target="_blank">figure S5</a> for behavior with lower mutation rates.…”

Effect of moderate elevated intra-abdominal pressure on lung mechanics and histological lung injury at different positive end-expiratory pressures by Mascha O. Fiedler (8714205)

“…In group C, there were no significant changes in EELV/kg (27±2 vs. 29±3 ml/kg), ΔP (10±1 vs. 12±1 cmH₂O) and ΔP_L (5±1 vs. 7±1 cmH₂O), but a significant decrease of C_stat (43±1 vs. 37±1 ml/cmH₂O; p<0.05). …”

Image 2_Bacillus Spizizenii FMH45-based biofertilizer enhances growth and halotolerance of cherry tomato plants under hydroponic cultivation systems.tif by Fatma Masmoudi (16819554)

“…Furthermore, HB45-treatment enhanced the plant oxidative stress response as evidenced by stable catalase activity, an approximately 50% reduction in lipid peroxidation markers such as malondialdehyde (MDA), and a 35% decrease in reactive oxygen species (ROS), including hydrogen peroxide (H₂O₂). …”

Data_Sheet_2_The Evolutionary Patterns of Genome Size in Ensifera (Insecta: Orthoptera).pdf by Hao Yuan (502114)

“…In our study, we used flow cytometry to determine the genome size of 32 species of Ensifera, the smallest one being only 1C = 0.952 pg with the largest species up to 1C = 19.135 pg, representing a 20-fold range. This provides a broader blueprint for the genome size variation of Orthoptera than was previously available. …”

Ficus regulates invasion and migration of cervical cancer cells. by Amit S. Choudhari (438151)

“…Tubulin was used as a loading control. (<b>G</b>) Densitometric analysis of the western blot showing fold change in HER-2 protein levels in SiHa and HeLa. …”

Data_Sheet_1_The Evolutionary Patterns of Genome Size in Ensifera (Insecta: Orthoptera).XLSX by Hao Yuan (502114)

“…In our study, we used flow cytometry to determine the genome size of 32 species of Ensifera, the smallest one being only 1C = 0.952 pg with the largest species up to 1C = 19.135 pg, representing a 20-fold range. This provides a broader blueprint for the genome size variation of Orthoptera than was previously available. …”

Data Sheet 1_Urinary microbiota changes among NMIBC patients during BCG therapy: comparing BCG responders and non-responders.docx by Toni Boban (20852165)

“…Non-responders exhibited a 12 times higher abundance of genus Aureispira (p<0.001), and, at the species level, a 27-fold lower abundance of Negativicoccus succinivorans (p<0.001). …”