Image_4_Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Ce... by Ursula Kreuser (9581357)

“…Importantly, the initial CHIR pulse increased cell proliferation until day 14 (five-fold), adjusted expression of adhesion-related genes (CDH3 up, CDH6 down) and increased extracellular matrix (ECM)-related gene expression (COL6, COL1, COL3, COL5, DCN, NPNT, LUM, MGP, MATN2, and VTN), thus yielding more matrix-interacting progenitors with a high aggregation capability. …”

MCU positively regulates melanogenesis while MCUb negatively controls melanogenesis. by Jyoti Tanwar (2230597)

“…<p><b>(A)</b> Schematic showing effect of MCU silencing on mitochondrial Ca²⁺ uptake. …”

The acute phase response in bats (Carollia perspicillata) varies with time and dose of the immune challenge by Matheus Viola (13933413)

“…APR components were assessed in rest and active periods after injection of three doses of LPS (5, 10 and 15 mg kg−1 LPS). The results indicate a more robust decrease in food intake at higher doses during the active period, while increased neutrophil/ lymphocyte ratio was more robust during the active period regardless of dose. …”

Supplementary Material for: Reduction in Body Weight but Worsening Renal Function with Late Ultrafiltration for Treatment of Acute Decompensated Heart Failure by Dev S. (4134922)

“…The median decrease in eGFR during UF was 4.5 ml/min/m² (IQR –13, 0; p <0.01) and 43% of patients experienced a ≥20% decrease in eGFR. …”

Lifetime Medical Costs of Obesity: Prevention No Cure for Increasing Health Expenditure by Pieter H. M van Baal (272522)

“…</p> <h3>Conclusions</h3><p>Although effective obesity prevention leads to a decrease in costs of obesity-related diseases, this decrease is offset by cost increases due to diseases unrelated to obesity in life-years gained. …”

Practical Prediction Model for Ovarian Insufficiency after Radiation by Gabriel Oliveira Bernardes Gil (13255037)

“…Results We obtained a linear function between ovarian radiation dose and loss of ovarian function (LOF) that is the percentage of decrease in the time to the ovarian failure compared with the time expected for a woman at the same age without irradiation exposition. …”

DataSheet1_Evaluation of drug-drug interaction between rilpivirine and rifapentine using PBPK modelling.docx by Sandra Grañana-Castillo (12013841)

“…The simulations of concomitant administration of rifapentine with rilpivirine at steady-state lead to a maximum decrease on AUC_0-24 and C_trough by 83% and 92% on day 5 for the daily rifapentine regimen and 68% and 92% for the weekly regimen on day 3. …”

FIGURE 2 from Proteasome Inhibition Reprograms Chromatin Landscape in Breast Cancer by H. Karimi Kinyamu (18387319)

“…Heat maps showing differential signal for non-phosphorylated (Non-P), and serine-5 phosphorylated (Ser5P) RNAPII at DOCRs that increase <b>(GAIN; A)</b> and decrease (<b>LOST; B</b>) accessibility. …”

NAC and trolox protect ATI-like cells treated with CSE. by Beata Kosmider (22264)

“…<p>Cells were exposed to CSE or co-treated with CSE and NAC or CSE and trolox for 24 h and toxicity was measured by propidium iodide and Hoechst 33342 double staining. A - Necrotic ATI-like cells after treatment with 5% CSE for 24 h. …”

Inhibition of the influenza virus RNP complex by 3′dGTP and T-705 RTP. by Zhinan Jin (432307)

“…<p>(A) Chemical structures of the obligate chain terminator 3′dGTP and the base-modified T-705 ribofuranosyl 5′-triphosphate (T-705 RTP). …”

<i>Drosophila</i> species develop at different rates and respond to temperature in distinct ways. by Steven G. Kuntz (555338)

“…<p>(A) Images of developing embryos of each species are shown to scale. …”

Results of the experiment. by Dezso Nemeth (354948)

“…<p>RTs of Session 1 (epoch 1–4) and Session 2 (epoch 5) for ASD (A), IQ-matched (B) and AGE-matched (C) control groups. …”

Luciferase assay results of <i>KATNA1</i> and <i>SPG4</i>. by Dolunay Kelle (6388055)

“…Luciferase assay was performed 48 h post-transfection, and calculated fold activities indicated that wt-Elk1 significantly decreased promoter + 5’ UTR activity of <i>KATNA1</i>. …”

Effects of P-gp inhibition on the retention of daunorubicin in the multidrug resistant prostate cancer cell line, DU145TXR. by Amila K. Nanayakkara (6812384)

“…<b>Panel C</b>–Fluorescence images of daunorubicin retention in the DU145TXR cells at the 105 min time point. After washing the cells with cold PBS as described in Methods, fluorescence micrographs were obtained using a Cytation 5 imager and a Texas Red filter. …”

Thoracoscopic Management of Spontaneous Pneumothorax by Christopher Komanapalli (13912363)

“…</p> <p>Once a bleb is identified it is held with a ring clamp and an EndoGIA stapler with a blue or green load (45/60mm length; 3.5/4.8mm staple) is introduced into the chest. …”

Macrophages are activated followed root avulsion/re-implantation. by Yuetong Ding (594520)

“…<p>In transverse sections at C5–C7, anti-CD11b immunoreactivity is widely distributed in the white and gray matter on the lesion side with a decreasing trend from day 7 to day 21, in both the control (A–C) and the mutant (D–F). …”

Stabilization of guava nectar with hydrocolloids and pectinases by Fernanda Döring Krumreich (4986089)

Stabilization of guava nectar with hydrocolloids and pectinases by Fernanda Döring Krumreich (4986089)

Purkinje cell degeneration in TRAF4-KO cerebellum. by Sébastien Blaise (332585)

“…(g, h) TUNEL staining: In the absence of TRAF4, the number of apoptotic Purkinje cells was increased (brown, arrows). Bars: a–d, g and h, 30 µm, insets 2-fold increase; e and f, 3.5 µm. …”

Elastic properties of an ensemble of myosin Ic molecules. by Florian Berger (4050247)

“…For a constant force of 20 pN an ensemble of <i>N</i> = 10 heads relaxes about 20 nm after decreasing the binding probability by a 100-fold (red line). …”