The interaction between C9orf72 and Rag GTPases. by Yon Ju Ji (3359057)

“…RagC levels were normalized against LAMP1 levels. [<i>p</i><0.5, and n = 3 for all groups]. Distribution of data points is presented with mean ± SD.…”

1,25D3 effects on proliferation, apoptosis and cumulative population doublings. by Barbara Klotz (189801)

“…The proliferation rate was decreased time-dependently after 1,25D3 treatment (gray bars) compared to control cells (black bars), with significant effects after 48 h and 72 h (A). 1,25D3 stimulation showed the strongest reduction of apoptosis rates after 72 h 1,25D3 treatment (gray bars) compared to control cells (black bars, B). …”

Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor by Olga Gorelenkova Miller (2900069)

“…Therefore, we anticipate that inhibition of Grx1 could be an anti-inflammatory therapeutic strategy. We used a rapid screening approach to test 504 novel electrophilic compounds for inhibition of Grx1, which has a highly reactive active-site cysteine residue (pKa 3.5). …”

Analysis of corneal neovascularization after corneal alkali burn. by Yifeng Ke (706040)

“…Statistics data are presented as mean ± standard deviation (n = 5). Two-way ANOVA analysis was performed to determine the significance of the difference between various treatment groups (* p<0.05, **p<0.01, ***p<0.001). …”

Pathway analysis of arginine and proline metabolism. by Jie Meng (152665)

“…<p>The map displays selected steps from KEGG map00330, ‘Arginine and proline metabolism’. A red rectangle indicates increased expression genes compared with salt 30, while blue indicates decreased expression of genes, and the gray rectangle indicates no significant changes. …”

Expression of BMPs and their endogenous inhibitors during progression and reversal of chronic kidney disease. by Anne-Cécile Huby (5653777)

“…Values are mean±SEM; n = 5, 9 and 13 for wild type and RenTg mice before and after irbesartan, respectively; * P<0,05 or ** P<0,01 vs WT; ^# P<0,05 or ^## P<0,001 vs RenTg.…”

Microvascular parameters by Marc Buise (22884)

“…<p><b>Copyright information:</b></p><p>Taken from "Intravenous nitroglycerin does not preserve gastric microcirculation during gastric tube reconstruction: a randomized controlled trial"</p><p>Critical Care 2006;10(5):R131-R131.…”

FFA- induced dysfunction and apoptosis of NIT-1 cells. by Huiping Yuan (358233)

“…<p>Palmitate and oleate (0.5 mmol/L, 48 h) decreased glucose-stimulated insulin secretion (GSIS, 20 mmol/L D-glucose in KRBH) (A), reduced insulin mRNA level shown by real-time PCR (B), induced apoptosis assessed by double-staining with Annexin V and PI (C) and increased lipid accumulation detected by Oil Red O Staining in NIT-1 cells (D). …”

Relationships between global hemodynamics, tissue oxygen tension (PO), and skeletal muscle lactate and ATP by Ryon M Bateman (2332)

“…</p><p>Copyright © 2003 BioMed Central Ltd</p> In a 6-hour rat model of sepsis (cecal ligation and perforation [CLP]), fluid resuscitation was found to prevent decreases in systemic oxygen delivery (DO) and tissue POin skeletal muscle (tPO). …”

cGMP production by mouse TG cultures. by Sandra Vilotti (103724)

“…Note large rise in cGMP that declines at 60 min; anantin alone (500 nM) decreases basal cGMP. Data were normalized to the total protein content in each sample and are presented as mean value ± SEM (n=3). …”

supplyment figure 1 for article by Wenlong Xue (7413242)

“…<p><b>The efficiency of</b> <b>miR-126-3p silencing, CSE and DNMT1 overexpression or DNMT1 silencing.</b> (a) miR-126-3p antagomir transfection decreased miR-126-3p expression by 74% in HUVECs compared with control. n = 6. …”

Pathway analysis of glycine metabolism. by Jie Meng (152665)

“…<p>The map displays selected steps from KEGG map00260, ‘Glycine, serine and threonine metabolism’. A red rectangle indicates increased expression compared with salt 30, and blue indicates decreased expression compared with salt 30. …”

Effects of METH self-administration on monoamine levels in the striatum. by Irina N. Krasnova (223517)

“…<p>METH caused persistent decreases in striatal DA levels (A), which negatively correlated with total drug intake when data at 24 hours, 7 and 14 days after cessation of self-administration were combined (B) and at 14 days post-drug (C). …”

SWFPL inhibits the proteolytic activity of intact Karilysin (Kly48) and delays the auto-processing of Kly48 to Kly18. by Peter Durand Skottrup (301019)

“…The SWFPL inhibitory effect was seen as a decrease in Relative Fluorescence Units (RFU) in a dose-response manner. …”

The effect of NAT administration on motor and sensory function following SCI. by Anna Victoria Leonard (568218)

“…<p>A modified Tarlov score was used to assess crude motor function (A), data is expressed as the median with individual data points plotted. …”

Cell viability and proliferation were examined in human glioma cells treated with miR-326 precursor. by Jingxu Zhou (433624)

“…<p>A172 (A) and U373 (B) cells were transfected with miR-326 precursor, control precursor, <i>NOB1</i> shRNA or nothing for 72 h as described in the methods section before measurement of the conversion of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) to a colored formazan product. …”

Relates to Fig 1. by He Liu (67509)

“…<p><b>Social stress induces social avoidance in susceptible mice. (A)</b> SI data showed that in the presence of a CD1 social target (nonaggressor), susceptible mice displaying: <b>(i)</b> decreased time in the interaction zone (<i>F</i>_2,9 = 5.185, <i>P</i> < 0.05), <b>(ii)</b> increased time in the corner zone (<i>F</i>_2,9 = 5.188, <i>P</i> < 0.05), and <b>(iii)</b> no difference in total travel between control, susceptible, and resilient mice. …”

Spatiotemporal release of DZNep and gemcitabine using engineered nanoparticles reduced drug dose while potentiating chemosensitivity. by Sau Wai Hung (102677)

“…Twenty-four hours after 5×10³ cells/well were seeded in a 96-well plate, cells were treated for 72 h. …”

Total nuclease activity, Dnase1 and Dnase1l1-3 expression in kidneys from BALB/c and (NZBxNZW)F1 mice. by Svetlana N. Zykova (134165)

“…<p>Pre-proteinuric and proteinuric B/W kidneys were used, the latter divided into 2 groups; one characterized by immune complex deposits in glomerular mesangial matrix only (labeled “Mesangial deposits”), and the other with immune complex deposits in both the mesangial matrix and the capillary membranes (labeled “Capillary deposits”). (<i>A</i>) Kidney lysates (black) or sera (grey), in which total protein was measured, and protein content of the samples normalized using BCA assay (Pierce), were applied onto 1% agarose gels containing calf thymus DNA and ethidium bromide in a CaCl₂- and MgCl₂- containing buffer, pH 7.6, and incubated in a humidified chamber at 37°C for 24 hours. …”

Inhibitory STDP interacts with excitatory STDP so as to favor balance among causal synaptic currents. by Nigel Stepp (683934)

“…Arrows pointing up indicate increasing excitatory effect, by either increasing excitatory weight or decreasing inhibitory weight. …”