ZnT1, MT and ZnT4 are all involved in the activation process of TNAP. by Shigeyuki Fujimoto (473814)

“…<p>(<b>A</b>) TNAP activity decreased in DT40 cells deficient in genes coding for c<i>ZnT1</i>, c<i>MT</i> and/or c<i>ZnT4</i> (<i>upper panel</i>). …”

Immunocytochemistry, RT-PCR and Q-PCR analyses of neonatal ‘RSCs’ during <i>in vitro</i> cultivation. by Magdalena Czekaj (314406)

“…<p>Following expansion in the presence of growth factors ‘RSCs’ show immunoreactivity for <i>nestin</i>, <i>Sox2</i> and <i>Pax6</i> at the protein (A) and mRNA levels (B, C). Further gene expression examination using semi-quantitative RT-PCR revealed that throughout all passages analyzed ‘RSCs’ express components of the notch signaling pathway (<i>Notch1</i> receptor, <i>Hes1</i> and <i>Hes5</i>). …”

Table_1_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

Table_3_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

Image_1_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.tiff by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

Serologic changes in 8 representative cases of sub-serostatus and clinical interpretation groups. by Ei Kinai (212480)

“…Note the abrupt increase in Anti-HBs from 24.9 to 1000 IU/mL in the third year of observation, followed by its decrease to 37.5 IU/mL by the fifth year. Although the parallel rise in aminotransferase and anti-HBc suggested exposure to HBV, HBV-DNA was negative throughout the observation period. …”

In vitro experiments yielded inconclusive results for predicting in vivo metastatic potential of L1CAM knockdown melanoma cells. by Ann-Kathrin Ernst (4846645)

“…In contrast to the Luc controls, surface L1CAM1 is reduced by more than 85% (MeWo) and apporoximately 75% (MV3) on the L1 kd cells (A). Proliferation assay: 5 X 10⁴ cells seeded per well and incubation for 48 h: Significant increase in proliferation for MeWo with L1CAM knockdown (L1 kd) compared with the MeWo Luc controls with unchanged surface L1CAM and significant decrease for MV3 L1 kd compared with MV3 Luc (B). …”

Table_4_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

Phosphorylation changes in GRP78 during sperm maturation by Vivian Lobo (831560)

“…</p><p></p><p></p><p>GP_4.96 increases in the mature caudal sperm. This may be due to a) phosphorylation of GP_5.43 (Purple dashed arrow) which is substantiated by the observed decrease in GP_5.43 in the mature sperm, or b) phosphorylation changes on GP_4.94, in the immature sperm as it traverses through the epididymis (Blue dashed arrow).…”

Table_2_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

Respiratory Exchange Ratio (RER) in ADKD and ADOX WT and OB mice. by Kazuhisa Watanabe (426012)

“…Data shown are mean ± SEM (8 mice per group) and run in a TSE systems indirect calorimeter for 48 hr. …”

General Health Questionnaire (GHQ12): new evidence of construct validity by Tulio Augusto Andrade Oliveira (14728698)

“…The study included 1,085 physicians with a mean age of 45.7 (SD = 10.6), mostly male (61.5%), married (72.6%) and Catholic (59.2%). …”

Reduced production of white blood cells (WBC) in <i>Iqgap2</i>^<i>-/-</i> mice. by Amr M. Ghaleb (668342)

“…Data are presented as the mean ± SEM. N = 3 per genotype/treatment (<b>A</b>), N = 5 per genotype/treatment (<b>B</b>), p-values indicating statistically significant differences are shown.…”

Impact of expanded PEP access on deaths, deaths averted and vial demand. by Malavika Rajeev (8544651)

“…<p>(A) Decrease in deaths due to rabies, (B) increase in total number of vials as additional clinics provisioning PEP are added at the national level, and (C) increase in vials needed per death averted based on the two models of reported bite incidence. …”

DataSheet1_Pooled-analysis of tadalafil and tamsulosin for ureteral calculi.docx by Fengze Sun (12259154)

“…But patients receiving 5 mg tadalafil decreased analgesia usage [MD = 101.04, 95% CI (67.56, 134.01), p < 0.00001].…”

<i>EPHA2</i> cataract mutations in the SAM domain. by Jeong Eun Park (166868)

“…Protein levels of <i>EPHA2</i> mutants are decreased in both HEK293T and αTN4-1 cells. The blot was reprobed with anti-α-tubulin as a loading control. …”

Effect of TNF-α on apoptosis in human eosinophils. by Hannu Kankaanranta (23356)

“…In (G and H) figures in top right corner represent percentages of Annexin-V positive cells (FITC+/PI- and FITC+/PI+). In (I) is shown the effect of neutralising TNF-α (A-TNF-α) antibody (5 µg/ml) on the inhibition of apoptosis induced by TNF-α. …”

Substance P inhibits K⁺ background conductance. by Carolina Thörn Pérez (773130)

“…Current traces from hyperpolarizing voltage steps applied to the same cell as in A during substance P bath application. C. The current-voltage relation (I-V) of the traces shown in A and B revealing a decrease in conductance with substance P (SP = substance P). …”

Temporal and geographical trends of HFRS cases and meteorological factors in Shandong, 2005–2019. by Qi Gao (133189)

“…(D) Geographical distribution of mean annual HFRS incidence for each 5-year period. …”

Dose and carbohydrate-binding dependent toxicity of <i>C. cinerea</i> galectin CGL2 towards <i>C. elegans</i>. by Alex Butschi (164200)

“…No significant difference was observed between latter two conditions (p>0.5). In the liquid assay, worm development decreases significantly at CGL2 concentrations higher than 150 µg/ml. …”