Improvement in the Mechanical Properties of Cell-Laden Hydrogel Microfibers Using Interpenetrating Polymer Networks by Fumisato Ozawa (3748114)

“…The in vivo functionality of the DN hydrogel microfiber was demonstrated by transplanting 3D assemblies of the microfibers into the intraperitoneal or subcutaneous space of diabetic mice, which successfully decreased their blood glucose levels. Thus, cell-laden DN hydrogel microfibers may represent a promising material for various biomedical applications.…”

Improvement in the Mechanical Properties of Cell-Laden Hydrogel Microfibers Using Interpenetrating Polymer Networks by Fumisato Ozawa (3748114)

“…The in vivo functionality of the DN hydrogel microfiber was demonstrated by transplanting 3D assemblies of the microfibers into the intraperitoneal or subcutaneous space of diabetic mice, which successfully decreased their blood glucose levels. Thus, cell-laden DN hydrogel microfibers may represent a promising material for various biomedical applications.…”

Improvement in the Mechanical Properties of Cell-Laden Hydrogel Microfibers Using Interpenetrating Polymer Networks by Fumisato Ozawa (3748114)

“…The in vivo functionality of the DN hydrogel microfiber was demonstrated by transplanting 3D assemblies of the microfibers into the intraperitoneal or subcutaneous space of diabetic mice, which successfully decreased their blood glucose levels. Thus, cell-laden DN hydrogel microfibers may represent a promising material for various biomedical applications.…”

Improvement in the Mechanical Properties of Cell-Laden Hydrogel Microfibers Using Interpenetrating Polymer Networks by Fumisato Ozawa (3748114)

“…The in vivo functionality of the DN hydrogel microfiber was demonstrated by transplanting 3D assemblies of the microfibers into the intraperitoneal or subcutaneous space of diabetic mice, which successfully decreased their blood glucose levels. Thus, cell-laden DN hydrogel microfibers may represent a promising material for various biomedical applications.…”

HIV-1 p17 oligomerization in solution depends on ionic strength. by Cinzia Giagulli (354803)

“…The detection of an approximately 40.000 Dalton band (trimeric p17) increases with the decreasing of NaCl concentration (lane A: p17 in NaCl 0.5 M; lane B: p17 in NaCl 0.2 M; lane C: p17 in NaCl 0.1 M), while p17 is mostly in a monomeric form in a solution containing 0.5 M NaCl. …”

Huntingtons Disease Mice Infected with <i>Toxoplasma gondii</i> Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality by David W. Donley (3111198)

“…<div><p>Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine-repeat expansion in the huntingtin protein. …”

Peroxide-induced disruption of secondary biochemical pathways. by Carlo Giannangelo (8053910)

“…Pathway enrichment analysis showing the percentage of significantly perturbed metabolites (Welch’s <i>t</i> test; P<i>-</i>value < 0.05 and fold change > 1.5) as a function of metabolite class for extended (3, 6 and 9 h) exposure with OZ277, OZ439 (both 300 nM) and DHA (100 nM). …”

3,3′-Diindolylmethane Induces G₁ Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells by Lyndsey E. Shorey (171162)

“…Treatment of the T-ALL cell lines CCRF-CEM, CCRF-HSB2, SUP-T1 and Jurkat with DIM <em>in vitro</em> significantly reduced cell proliferation and viability at concentrations 8- to 25-fold lower than the parent compound I3C. DIM (7.5 µM) arrested CEM and HSB2 cells at the G₁ phase of the cell cycle and 15 µM DIM significantly increased the percentage of apoptotic cells in all T-ALL lines. …”

Efficacy of Rituximab in Refractory Inflammatory Myopathies Associated with Anti- Synthetase Auto-Antibodies: An Open-Label, Phase II Trial by Yves Allenbach (483114)

“…Corticosteroid doses decreased from 52.5 mg/d (range, 10–70) to 9 mg/d (range, 7–65) and six patients had a decrease in the burden of their associated immunosuppressants. …”

Image_1_Quantitative Profiling of Oxylipins in Acute Experimental Intracerebral Hemorrhage.TIF by Jun-Jie Yuan (8552463)

“…The most commonly increased oxylipins in ICH were derived from AA (10/17) and EPA (4/17) followed by LA (2/17) and DHA (1/17). 18-HEPE from EPA was the only oxylipin that remained significantly increased from 0.5 to 3 days following ICH. Furthermore, 14 of the increased oxylipins reached a peak level on the first day of ICH, and soon decreased while five oxylipins (PGJ2, 15-oxo-ETE, 12-HEPE, 18-HEPE, and 5-oxo-ETE) had increased 3 days after ICH suggesting that the profile shifted with the progression of ICH. …”

Anionic Cerium Oxide Nanoparticles Protect Plant Photosynthesis from Abiotic Stress by Scavenging Reactive Oxygen Species by Honghong Wu (4583449)

“…Plant abiotic stress leads to accumulation of reactive oxygen species (ROS) and a consequent decrease in photosynthetic performance. …”

DataSheet_1_Radiation-induced circulating microRNAs linked to echocardiography parameters after radiotherapy.zip by Justyna Chałubińska-Fendler (3547673)

“…Among those miRNAs: miR-15b-5p, miR-22-3p, miR-424-5p and miR-451a were confirmed to show significant decrease of expression 24 hours post-RT in the validation cohort. …”

Projected Impact of the Medicare Part D Senior Savings Model (SSM) on Diabetes-Related Health and Economic Outcomes among Insulin Users Covered by Medicare by Hui Shao (316404)

“…</p> <p><strong>Methods: </strong>Data for Medicare beneficiaries with diabetes treated with insulin were extracted from the 2018 Medical Expenditure Panel Survey. A validated diabetes microsimulation model estimated health and economic impacts of the new policy for the 5-year initial implementation period and a 20-year extended policy horizon. …”

Table_1_Quantitative Profiling of Oxylipins in Acute Experimental Intracerebral Hemorrhage.DOCX by Jun-Jie Yuan (8552463)

“…The most commonly increased oxylipins in ICH were derived from AA (10/17) and EPA (4/17) followed by LA (2/17) and DHA (1/17). 18-HEPE from EPA was the only oxylipin that remained significantly increased from 0.5 to 3 days following ICH. Furthermore, 14 of the increased oxylipins reached a peak level on the first day of ICH, and soon decreased while five oxylipins (PGJ2, 15-oxo-ETE, 12-HEPE, 18-HEPE, and 5-oxo-ETE) had increased 3 days after ICH suggesting that the profile shifted with the progression of ICH. …”

Evaluation of ocular surface in children with attention deficit hyperactivity disorder with respect to methylphenidate treatment by Emre Aydemir (13106446)

“…However, Group B showed a significant decrease in tear film break-up time (10.50 ± 3.39 vs. 12.52 ± 2.46 s; p=0.005), tear meniscus height (307.40 ± 5.53 vs. 310.82 ± 7.30 µm; p=0.025), tear meniscus area (0.024 ± 0.0037 vs. 0.026 ± 0.0046 mm2; p=0.010) and Schirmer test (12.75 ± 3.96 vs. 15.41 ± 3.75 mm; p=0.004) results compared with Group A. …”

Comparison of Homer 1 isoforms ratio in adult (Y), AI and AU hippocampal formation. by Caroline Ménard (189955)

“…Conversely, this ratio was decreased in synaptosomes of AU animals. E) Graphs for average Homer 1 protein levels bound to mGluR5 in the PSD and synaptosomes of each group. …”

Hydrogen sulfide mediates 4-hydroxynonenal induced hepatic cell death in alcoholic liver disease by Bin Ding db@zcmu.edu.cn (4861096)

“…<b>Figure 1. </b>4-HNE decreased cell viability.<b>A: </b>4-HNE decreased cell viability in a dose-dependent manner as shown by MTT assay. …”

Disrupted elncRNA splicing impacts <i>cis</i>-gene regulation. by Jennifer Yihong Tan (11933872)

“…<p>(Top panels) Representation of the differential splicing events between samples with different genotypes for elncRNAs, (A) ENSG00000250903, (B) ENSG00000227388 and (C) XLOC_013468. …”

Differentially expressed genes related to cell proliferation in zebrafish spinal cord after injury and validation of cell cycle regulators. by Subhra Prakash Hui (510710)

“…Red and green colors represent increased and decreased expression respectively. C–F) Quantitative RT-PCR analysis of <i>ccnd1</i> (C), <i>cdk2</i> (D), <i>ccne</i> (E) and <i>ccnb1</i> (F) showing fold change and pattern of expression at different time points after injury. …”

Open Field. by Raina D. Pang (345662)

“…<p>A) 5-HTT KO mice show significantly decreased distance traveled throughout the arena in a novel open field. …”