Effect of BXL-01-0029 on IFNγ+TNFα-induced class I and class II HLA in Hfsmc. by Luigi Di Luigi (478292)

“…<p>A, Immunocytochemistry revealed no constitutive expression of class I and class II HLA in control Hfsmc (left A); positive staining for both antigens was observed after 24–48 h incubation with IFNγ+TNFα (middle A); BXL-01-0029 significantly counteracted cytokine-induced class II HLA expression at both time points, with no effect onto class I HLA (right A). …”

Data_Sheet_1_Lactoferrin/sialic acid prevents adverse effects of intrauterine growth restriction on neurite length: investigations in an in vitro rabbit neurosphere model.docx by Britta Anna Kühne (13138533)

“…We established for the very first time a protocol to cultivate control and IUGR rabbit neurospheres not only for 5 days but under long-term conditions up to 14 days under differentiation conditions. …”

Overexpression of estrogen receptor-α inhibited the production of terminally arrested progeny. by Mine Mumcuoglu (246981)

“…<p>(<b>A</b>) ER-overexpressing (ER-5, ER-7, ER-26) and control (C-8, C-10, C-11) clones were established from T47D cells and tested for ER expression by western blotting using decreasing amounts of total proteins. …”

Figure 2 by Yixin Yang (409184)

“…The data are presented as the mean ± SD; p<0.05. Both the size and number of the colonies formed in soft agar were decreased in 5-8F/LPLUNC1 cells compared with 5-8F/vector cells.…”

Table_1_Dehydroepiandrosterone Antagonizes Pain Stress-Induced Suppression of Testosterone Production in Male Rats.DOCX by Qiqi Zhu (5025422)

“…When 5 and 10 mg/kg DHEA were orally administered to rats 0.5 h before starting pain stimulation, DHEA prevented pain-mediated decrease in plasma T levels and the expression of Star, Hsd3b1, and Cyp17a1 without affecting plasma CORT levels. …”

Mathematical model predictions of the detyrosination inhibition with experimental validation in proliferative cells. by Jeremy Grignard (12963351)

“…The BIOCHAM command draws a dose-response diagram by linear variation of the initial concentration (the dose) of the input object, here <i>k</i>₁, and plotting the output object (the response), here the molecular species: Tyr, Detyr and TyrDetyr, showing an increase of the tyrosination status with a decrease of <i>k</i>₁. …”

Plasma corticosterone at induction. by Emilia M. Lefevre (3944765)

“…A main effect of Day was also observed at this time point. …”

Heterochromatin levels decline with aging. by Kimberly Larson (186316)

“…<p>(A) Gut tissues from young (3-day old) and old (35-day old) female flies were dissected and stained with anti-HP1 (magenta). …”

Table1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.docx by Ádám István Horváth (15443678)

“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkable weight bearing and paw withdrawal threshold decrease, alterations in the tibial and femoral structures (decreased trabeculation and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining, disrupted tidemark integrity, synovial hyperplasia, and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord.…”

Table_1_Inhibitory and excitatory responses in the dorso-medial prefrontal cortex during threat processing.docx by Venkata C. Chirumamilla (6792758)

“…At source level, ICF led to an increase and short intracortical inhibition (SICI) to a decrease of theta power in the bilateral dmPFC, relative to single pulse TMS during 0–0.5 s. …”

Improving the Manchester Triage System for Pediatric Emergency Care: An International Multicenter Study by Nienke Seiger (509615)

Image2_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkable weight bearing and paw withdrawal threshold decrease, alterations in the tibial and femoral structures (decreased trabeculation and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining, disrupted tidemark integrity, synovial hyperplasia, and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord.…”

Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkable weight bearing and paw withdrawal threshold decrease, alterations in the tibial and femoral structures (decreased trabeculation and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining, disrupted tidemark integrity, synovial hyperplasia, and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord.…”

Image1_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF by Ádám István Horváth (15443678)

“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkable weight bearing and paw withdrawal threshold decrease, alterations in the tibial and femoral structures (decreased trabeculation and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining, disrupted tidemark integrity, synovial hyperplasia, and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord.…”

Image_1_Inhibitory and excitatory responses in the dorso-medial prefrontal cortex during threat processing.TIF by Venkata C. Chirumamilla (6792758)

“…At source level, ICF led to an increase and short intracortical inhibition (SICI) to a decrease of theta power in the bilateral dmPFC, relative to single pulse TMS during 0–0.5 s. …”

Cardiovascular genes are dysregulated in FVB/N KLF2−/− AV region. by Aditi R. Chiplunkar (282141)

“…(<b>A–C</b>) In E10.5 FVB/N KLF2−/− AV region there is significantly decreased expression of (<b>A</b>) Tbx5 (p = 0.0175), (<b>B</b>) Gata4 (p = 0.0164) and (<b>C</b>) Sox9 (p = 0.019) mRNA compared to FVB/N WT, but Mix WT and Mix KLF2−/− hearts have no differences in expression of these genes. …”

LPLUNC1 inhibited the expression of important molecules in the cell cycle pathway. by Yixin Yang (409184)

“…There was no difference in the expression levels of cyclin A and B between 5-8F/LPLUNC1 and 5-8F/vector cells. …”

() Geometry of the magnetic tweezer experiment with FtsK by Timothée Lionnet (21867)

“…This effect tends to increase the bead height, as seen in the experimental trace, and continues until all plectonemes have been removed. At this point, the DNA length decreases due to loop extrusion alone, as in (A). …”

ZnO−Al₂O₃ and ZnO−TiO₂ Core−Shell Nanowire Dye-Sensitized Solar Cells by Matt Law (1296396)

“…However, titania shells 10−25 nm in thickness cause a dramatic increase in <i>V</i>_OC and fill factor with little current falloff, resulting in a substantial improvement in overall conversion efficiency, up to 2.25% under 100 mW cm^-2 AM 1.5 simulated sunlight. …”

Image_3_Optimal Ranges and Thresholds of Grape Berry Solar Radiation for Flavonoid Biosynthesis in Warm Climates.tif by Nazareth Torres (3571967)

“…Although some berry traits were improved (i.e. 2.5° Brix increase in berry total soluble solids) due to canopy management practices (ST), this resulted in a four-fold increase in labor operations cost, two-fold decrease in yield with a 10-fold increase in anthocyanin production cost per hectare that should be assessed together.…”