The Conserved Lid Tryptophan, W211, Potentiates Thermostability and Thermoactivity in Bacterial Thermoalkalophilic Lipases by Emel Timucin (503760)

“…Further thermoactivity and CD spectroscopy analyses showed that W211A also led to a strong decrease in the optimal and the melting temperature of BTL2, implying stabilization by W211 also to the intramolecular interactions. …”

Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity by Wayne Chadwick (165106)

“…Amitriptyline treatment also caused a significant potentiation of non-toxic Aβ monomer with a concomitant decrease in cytotoxic dimer Aβ load, compared to vehicle-treated 3×TgAD controls. …”

Description of research subjects. by Tulus Winarsunu (16324693)

“…There is a decrease in hopelessness and an increase in internal locus of control in people with DM given hope therapy.…”

Intrapericardial Delivery of Gelfoam Enables the Targeted Delivery of Periostin Peptide after Myocardial Infarction by Inducing Fibrin Clot Formation by Brian D. Polizzotti (166489)

“…Intrapericardial administration of drug-eluting hydrogels may provide a clinically viable strategy for increasing myocardial retention, therapeutic efficacy, and bioactivity of rPN and to decrease systemic re-circulation.…”

Motor activity defects in old Gas7-deficient mice. by Bo-Tsang Huang (162584)

“…Data points are mean ± SEM, ***<i>P</i><0.001. (B) Adult Gas7-deficient mice performed no differently in regards to latency time than wild-type mice in four independent rotarod tests performed at constant speed (n  = 22) (left panel). …”

Different types of responses in PNC neurons evoked by depolarizing current injections by Nora Prochnow (4627)

“…Resting potentials of the cells were -61.6 mV, A, -62.5 mV, B, -61.2 mV, C, -58.4 mV, D, and -50.9 mV, E. …”

Changes in the perinuclear actin stress fibers and nuclear geometry for different rigidities. by Renu Vishavkarma (633732)

“…<p>(a–d) The observed decrease in stress fiber density as function of substrate rigidity for substrates with elastic modulus 65 kPa, 23 kPa, 5 kPa and 3 kPa respectively (also see panel in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107895#pone.0107895.s011" target="_blank">Fig. …”

Data partition and aggregation procedures. by Itziar Frades (741552)

“…<p>A random partition of the data into mutually exclusive sets P₁, P₂, P₃, P₄ and P₅ is done. …”

Lack of cluster formation upon unilateral PLL addition. by Yuri N. Antonenko (241873)

“…<p>Unilateral PLL addition at a concentration of 2.5 µM per lysine monomer, only has a minor effect on the lifetime <i>τ_P</i> of OPg dimers even at 1 M KCl on the opposite side. …”

Signalling via the Ras-RAF arm of ERK-MAPK is required for HCMV reactivation. by Verity G. Kew (577428)

“…IE RNA expression was expressed as a fold decrease compared to mock treated control <b>C</b>) immature DCs (1) were incubated with DMSO (2,3) or ERK (4,5), tpl2 (6,7) and Raf (8,9) inhibitors for 1 hour then stimulated with LPS (black) or IL-6 (grey) to promote reactivation. …”

Microarray analyses of the transcriptome of diploid (D) and tetraploid (T) HCT116 cells treated with cisplatin, Chk1 inhibitor or the combination of both. by Ilio Vitale (82793)

“…Each row represents the combination of two dye-swap experiments compared to untreated control cells and each column represents a single gene. Red and green colors indicate an increase and a decrease, respectively, in the expression of genes as compared to unstimulated control cells. …”

Suppression of APP maturation and proteolytic metabolism by the PDZ domains of X11 proteins. by Yuhki Saito (145216)

“…Concentrations of Aβ40 (left) and Aβ42 (right) are shown as means ± s.e. …”

NCS1 overexpression promotes functional recovery. by Ping K. Yip (247093)

“…<p>(A–B) In the staircase reaching test, no significant decrease in either the numbers of food pellets displaced or eaten was observed at later time points after treatment with HIV-GFP-NCS1 compared to that of the sham rats. …”

Repetitive stress modulates loudness perception. by Ghattas Bisharat (20706928)

“…We define the perceptual boundary as the intensity where the psychometric fit to the choice function, crosses PLoud = 0.5. Mice exhibited increased perceptual boundaries during repeated stress, indicating a decreased loudness perception (<i>t</i> test, <i>p</i> = 1.2 × 10⁻⁰⁵, mean ± SE). …”

<i>In vitro</i> fluorescence imaging and physicochemical characterization of the 3WJ-n × Bro fluorescent aptamer. by Sha Liu (80416)

“…T_m represents the temperature at which fluorescence intensity decreases to 50% of the initial value. Error bars represent mean ± SD (n = 5). …”

Supplementary data to publication “Plasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction” by kang yong (10328758)

Asymmetric ratification standards and popular perceptions of legitimacy by Dominik Schraff (4587325)

Impact of bariatric surgery on depression and anxiety symptons, bulimic behaviors and quality of life by Bárbara Tae (12718922)

Impaired <i>M</i>. <i>tuberculosis</i> Antigen-Specific IFN-γ Response without IL-17 Enhancement in Patients with Severe Cavitary Pulmonary Tuberculosis by Lin Fan (281949)

“…We also found a decrease in the proportion of CD3+CD4+ T cells in the blood of severe cavitary PTB patients (p < 0.05).…”

Stimulation of osteoclasts and osteoblasts by PC3c cells <i>in vitro</i>. by Anaïs Fradet (460958)

“…Mineralized bone nodule formation was decreased when primary cells were treated with conditioned medium from any of the PC3/PC3c cells (compared with non-treated (Ct) cells); the decrease was less when PC3c cell conditioned medium was used (compared with PC3) (ANOVA, p<0.001 versus Ct and versus PC3). …”