PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

The authorship rating was a 6-point rating scale of the degree of authorship, ranging from 1 “I could not manipulate the window at all” to 6 “I completely manipulated the window”.... by Junhui Kim (18575083)

Subjects:

Direction and magnitude of change in non-TOL group vs. TOL and control: Genes with decreased expression in non-TOL group. by Joseph Pidala (702976)

Decreased retinal cell density is associated with increased cell death in <i>Lrp2</i>^{<i>FoxG1</i>.<i>cre-KO</i>} mutant eyes. by Olivier Cases (760028)

HoxA9 represses and C/EBPα activates the <i>Cebpa</i> +8 kb enhancer in immature myeloid cells. by Lei Peng (260321)

Subjects:

HDACi decrease NK function. by Matthew Pace (2954127)

Decrease in GABA in APP mice. by Ksenia V. Kastanenka (3692380)

Ibuprofen and diclofenac decrease proliferation. by Verena Leidgens (815986)

“…<p>Proliferation was analyzed using crystal violet staining and results were verified via the CyQuant Direct Cell Proliferation assay in HTZ-349. (A) Starting at 72 h, all ibuprofen concentrations (0.5, 1, 2 mM) resulted in significant reduction of HTZ-349 proliferation (compared to non-treated Ctrl, 95% CI, p < 0.05). 2 mM ibuprofen caused significant proliferation inhibition at 24 h (0.01 > p ≤ 0.001) and 48 h (p < 0.0001). …”

Lipopolysaccharide (LPS) treatment decreases the density of neurons in the ischemic cortical region after stroke in a microglia-dependent manner. by Eric Yuhsiang Wang (17131666)

Snow-covering and snow-free soil temperature (T) in (a) control, (b) low burn severity, and (c) high burn severity. by Tongxin Hu (4217563)

Effect of high-fructose (HFr) supplementation (500 μM) on markers of oxidative stress and HO-1 and SIRT1 gene expressions in hepatocytes treated with and without CoPP (5 μM) and Sn... by Komal Sodhi (540891)

Fisetin preserve lipid homeostasis in HFD-fed mice. Serum levels of lipid biochemical parameters in mice. (a) Triglyceride (TG), (b) Total cholesterol (TC), (c) LDL-C and (d) HDL-C... by Mahboobe Sattari (20622143)

MeV induced <i>APOBEC3A</i> upregulation. by Pierre Khalfi (7868252)

Overexpression of ATX delays retinal vascularization and decreases vessel branching. by Hiroshi Yukiura (741223)

Annexin A2 accumulates in the nucleus and decreases in the cytoplasm in response to genotoxic agents. by Patricia A. Madureira (114480)

DA receptor agonist pramipexole reduces generosity reference-point (V). by Sergio Oroz Artigas (8207559)

VPA decreases cell proliferation. by Muriel Rhinn (406515)

Rapamycin decreases phosphorylation of S6. by Adam L. Hartman (308128)

Prevalence reduction of overall obesity in 2022–2027, according to a decrease in the probability of move up one BMI class and an increase in the probability of move down one BMI cl... by Pierre Bauvin (18154818)

“…Scenarios 1 and 2 were built up to obtain a stabilization of the overall obesity prevalence: scenario 1 corresponds to a 22% decrease in the probability of move up one BMI class, and scenario 2 corresponds to a 33% increase in the probability of move down one BMI class. …”

HIV Tropism and Decreased Risk of Breast Cancer by Nancy A. Hessol (191696)