Waterfall plot showing the quantitative changes in ER, PR, and Ki-67 expression. by Yuqin Ding (623253)

“…(A) ER discordance rate: 10.4% (50/482) of patients, including 36 (7.5%) patients with positive-to-negative conversion and 14 (2.9%) patients with negative-to-positive conversion; (B) PR discordance rate: 17.0% (82/482) of patients, including 57 (11.8%) patients with positive-to-negative conversion and 25 (5.2%) patients with negative-to-positive conversion; (C) Ki-67 discordance rates: 50.4% (243/448) of patients had decreased expression and 27.0% (130/448) of patients had increased expression.…”

IL-1β depletion and IL-1 receptor antagonist treatment alleviated the neutrophilic inflammation. by Wen-Cheng Chao (2817868)

“…<p>The characteristic pulmonary histopathological images (A) of <i>M</i>. <i>marinum</i>-infected <i>Ncf1</i>^<i>-/-</i> mice and WT mice on day-5 with and without IL-1β depletion by a monoclonal antibody directed against IL-1β (150μg on day-1). …”

Adaptation period to diets with low or high fiber on digetibility and faecal characteristics in dogs by T. Ramos (7501706)

“…Fecal consistency of the dogs did not differ among diets and periods (P> 0.05). There was a decrease in fecal pH and ammonia in dogs fed the diet with 15% SH (P< 0.05) after 10 days of feeding (P< 0.05). …”

Artifacts in FRAP arising from the strength of the intentional photobleach. by Tatsuya Morisaki (631489)

“…Artifactual recoveries were observed with the GFP tag (A) but not the TMR-Halo tag (B). Consistent with previous studies <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0107730#pone.0107730-Mueller2" target="_blank">[9]</a>, the relative size of the recovery with the GFP-tag increased with decreasing strength of the photobleach (colored curves in A). …”

<i>In vivo</i> luciferase detection of hAFSC in ATN damaged kidneys. by Laura Perin (252948)

“…The optical signal is strongly present during the first 5 hours post injection (panel 2–5), decreases over time (panel 6–8), but is still present after 21 days (panel 9). …”

Isolation and characterization of brain derived EVs. by Sowmya V. Yelamanchili (482686)

“…Analysis revealed significantly increased expression of miR-21-5p, miR-100-5p and miR-146-5p, and decreased expression miR-126-5p, in SIVE. …”

RSK2 regulates DNA repair efficiency under conditions of genotoxic stress. by Han Chi Lim (439624)

“…<p>A. Increased formation of AD-induced γH2AX foci in RSK2 KO MEFs. …”

Only spaced (but not massed) learning allowed long-term retention of an associative olfactory task and increased neurogenesis. by Florence Kermen (362513)

“…<p><b>A</b>. Experimental design. For the spaced conditioning (<b>Ai</b>) BrdU was injected 14 days prior to training which occurred over 5 days (4 trials per day). …”

The NK1-receptor antagonist ezlopitant significantly inhibits both sucrose and ethanol operant self-administration in rats. by Pia Steensland (362091)

“…<p>Ezlopitant (2, 5, 10 mg/kg i.p.) dose dependently decreases self-administration of 5% sucrose (<b>A</b>). …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

T-helper cell pathway diagram. by Josephine S. D’Alessandro (814578)

“…Gray lines indicate members of a group. APCs, antigen-presenting cells; CXCR1, chemokine (C-X-C motif) receptor 1; CXCR3, chemokine (C-X-C motif) receptor 3; CXCR5, chemokine (C-X-C motif) receptor 5; CXCL10, chemokine (C-X-C motif) ligand 10; GA, glatiramer acetate; HLADMA, major histocompatibility complex class II, DM alpha; HLADMB, major histocompatibility complex class II, DM beta; HLADQB1, major histocompatibility complex class II, DQ beta 1; ICOSLG, inducible T-cell costimulatory ligand; IL-4, interleukin-4; MHC class II, major histocompatibility complex class II; LTB, lymphotoxin beta (tumor necrosis factor superfamily, member 3); MYD, myeloid differentiation primary response protein; S100A10, S100 calcium-binding protein A10; STAT, signal transducer and activator of transcription; TCR, T-cell receptor; Th, T-helper.…”

Testosterone, Sex Hormone-Binding Globulin and the Metabolic Syndrome in Men: An Individual Participant Data Meta-Analysis of Observational Studies by Judith S. Brand (494813)

DataSheet1_Spatiotemporal changes and driving factors of reference evapotranspiration and crop evapotranspiration for cotton production in China from 1960 to 2019.docx by Yuexia Su (16936038)

“…WS showed a significant decrease in ET_O in the northwestern inland cotton region. …”

Investigating the Effect of Different Treatments with Lactic Acid Bacteria on the Fate of <i>Listeria monocytogenes</i> and <i>Staphylococcus aureus</i> Infection in <i>Galleria me... by Athena Grounta (3115224)

“…It was observed that the time (6 or 24 h) and type (live or heat-killed cells) of challenge period with LAB prior to infection greatly affected the survival of infected larvae. The highest decrease of <i>L</i>. <i>monocytogenes</i> population in the hemolymph was observed in groups challenged for 6 h with heat-killed cells by an average of 1.8 log units compared to non challenged larvae for strains B281 (<i>p</i> 0.0322), B282 (<i>p</i> 0.0325), and LGG (<i>p</i> 0.0356). …”

Multisite Phosphorylation Provides an Effective and Flexible Mechanism for Switch-Like Protein Degradation by S. Marjan Varedi K. (235441)

“…A single-site protein cannot convert a graded input of kinase increase to much sharper output, whereas multisite phosphorylation is capable of generating a highly switch-like temporal profile of the substrate protein with two characteristics: a temporal threshold and rapid decrease beyond the threshold. …”

Redox status of rat cortical neurons. by Inmaculada Posadas (218859)

“…V stands for vehicle (DMSO 1‰)-treated cells. Data represent the mean ± SEM of 9 independent experiments. ***, p<i><</i>0.001 as compared to vehicle-treated cells (V); ^###, p<i><</i>0.001 compared to AAP 2 mM (A2). …”

Citalopram does not increase neural signals for reward or effort outcomes. by Jacqueline Scholl (3752851)

“…On the contrary, a more lenient time point—by—time point <i>t</i> test analysis of the time courses revealed that in striatum and vmPFC, citalopram, in fact, decreased the relative reward magnitude outcome signal late in the outcome phase (*<i>p</i> < 0.05 for time point—by—time point two-sided <i>t</i> tests). …”