Heat-killed <i>A</i>. <i>persici</i> shortens lifespan and increases the host defence but does not enhance paraquat resistance. by Taro Onuma (15195377)

The effect of GuHCl on the absorbance spectra of Rtms5^Y67F and Rtms5^Y67F/H146S. by Jion M. Battad (127989)

“…<p>Rtms5^Y67F (A) and Rtms5^Y67F/H146S (B) were diluted to a final protein concentration of 0.15 mg/ml in 0.1 M Tris-HCl (pH 8.0), 6 M GuHCl, and the absorption spectra determined at selected time points after incubation at 21°C. …”

A role for <i>bmm</i> in the regulation of sex differences in triglyceride homeostasis. by Lianna W. Wat (8339454)

“…(E) Triglyceride levels were lower in 1-day-old <i>bmm</i>^<i>rev</i> males compared with newly eclosed <i>bmm</i>^<i>rev</i> males (<i>p</i> = 0.0013; Student <i>t</i> test); however, there was no significant difference in whole-body triglyceride levels between 1-day-old <i>bmm</i>^<i>1</i> males and newly eclosed <i>bmm</i>^<i>1</i> males (<i>p</i> = 0.0793; Student <i>t</i> test). (F) In 5-day-old <i>bmm</i>^<i>rev</i> males, whole-body triglyceride storage significantly decreased between 0 and 12 hours STV, with a further reduction between 12 and 24 hours STV (<i>p</i> = 6.2 × 10⁻⁵ and 2.4 × 10⁻³, respectively; one-way ANOVA followed by Tukey HSD test). …”

Mechanistic Insights on the Inhibition of C5 DNA Methyltransferases by Zebularine by Christine Champion (243238)

“…First, we observe an increase in the DNA binding when zebularine is incorporated into the DNA, compared to deoxycytidine and 5-fluorodeoxycytidine, together with a strong decrease in the dissociation rate. …”

Replacement of intra- and extracellular chloride for D-gluconate eliminated statistically significant decreases in GLT-1 stoichiometric current and the current/flux ratio in 100–30... by Anatoli Y. Kabakov (729047)

Development of a novel bioreactor and systems for suspension cell culture in biopharmaceutical production by Rajesh Sharma (6183845)

“…The heat flow data (metabolic heat) from the treated and normal cells showed a distinct decrease in the heat generation profile which indicated that the treated cells were viable but not as active as the normal (non-treated) cells. …”

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD4⁺ and CD8⁺ naïve T cells as compared to WT septic mice. by Katherine T. Fay (2576998)

“…B) CD43^-/- septic mice exhibited a decreased frequency of apoptotic naïve CD4⁺ T cells, defined as 7-AAD⁺ Annexin V⁺ CD44^LO CD62L^HI CD4⁺ cells, compared to WT septic mice (11.8±1.6 vs 18.8±1.3, p = 0.002. …”

CBD (30 mg/kg, n = 7–9 animals/group) and HU-101 (10 mg/kg, n = 9–10 animals/group) decreased the number of buried marbles in the MBT. by Aviva Breuer (3153021)

Inflammation Regulates TMPRSS6 Expression via STAT5 by Delphine Meynard (87311)

“…The downregulation of Tmprss6 by inflammation in mice is not dependent on the Bmp-Smad pathway but occurs through a decrease in Stat5 phosphorylation. Moreover, Stat5 positively regulates Tmprss6 expression directly by binding to a Stat5 element located on the Tmprss6 promoter. …”

Supplementary Material for: Waning of SARS-CoV-2 Vaccine-Induced Immune Response over 6 Months in Peritoneal Dialysis Patients and the Role of a Booster Dose in Maintaining Seropos... by Murt A. (9984845)

“…Humoral immune responses were measured by a commercial test that detects antibodies toward the receptor-binding domain of the spike protein of SARS-CoV-2. …”

<i>T</i>. <i>spiralis</i> IIL ESP reduced TJ protein expression and destroyed the integrity of Caco-2 monolayer. by Qi Qi Lu (17721401)

Image5_Spinel harzburgite–derived silicate melts forming sulfide-bearing orthopyroxenite in the lithosphere. Part 2: Sulfide compositions and their chalcophile and highly siderophi... by A. Bénard (13030182)

Transitioning of people with T1D from Multiple Daily Injections (MDI) and Self-Monitoring of Blood Glucose (BGM) directly to MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system... by Bartłomiej Matejko (13180606)

“…</p> <p>Results: 41 participants were recruited and randomized to either the AHCL (20) or the MDI+BGM (21) group. 37 participants (age 40.3±8.0 years; duration of diabetes 17.3 ± 12.1 years; BMI 25.1±3.1 kg/m2; HbA1c 7.2% ± 1.0) completed the study. Time spent in target (TIR) increased from 69.3±12.3% at baseline to 85.0±6.3% at 3 months in the AHCL group, while remaining unchanged in the control group: treatment effect 21.5% [95% CI 15.7, 27.3%]; p < 0.001. …”

Echocardiography calculation results for 9-year-old ewes. by Christopher L. Pankey (13607874)

Fetal aorta sections. by Christopher L. Pankey (13607874)

Adjusted Hazard Ratios (HRs) for death risks according to handgrip strength. by Kaihong Xie (13955203)

Data_Sheet_1_rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.docx by Munal B. Kandel (18526539)

“…This study tested the hypothesis that novel JDNI8 replication-defective herpes simplex-1 viral vectors (rdHSV) carrying a CA8 transgene (vHCA8) reduce primary afferent neuronal excitability. …”

Table_1_Decreased circulating dipeptidyl peptidase-4 activity after short-term intensive insulin therapy predicts clinical outcomes in patients with newly diagnosed type 2 diabetes... by Jie Chen (5892)

“…After three months post-SIIT, DPP-4 activity remained stable in the remission group (39.63 ± 8.53 nmol/L) but increased in the non-remission group (42.34 ± 6.64 nmol/L). This resulted in a more pronounced decrease in DPP-4 activity from baseline in the remission group (-3.39 ± 8.90 vs. -1.10 ± 8.95, P = 0.035). …”

Changes in the prevalence rates of age-related macular degeneration (AMD) subtypes in 1,600 patients. by Masaaki Saito (259172)

Nanoprobe laminin affinity and toxicity measurements. by Juan F. Zapata-Acevedo (18349423)