Hypoxia upregulates protein levels of the regulatory subunits p35 and p25 but not CDK5. by Bo S. Kim (716088)

“…Also shown is a decreased protein level of the cleaved fragment p10, a known inhibitor of CDK5 activity (A and B).…”

Significantly associated microbial species between the pre- and post-eradication states (at a significance level <i>p</i><0.05). by Dita Gudra (4439767)

V1 developmental data appear to challenge the canonical sparse coding models. by Joel Zylberberg (340947)

“…<p>Multi-unit activity in primary visual cortex (V1) of awake young ferrets watching natural movies shows decreasing sparseness over time. …”

Proper Notch signaling is required for the differentiation of <i>agr2</i>^<i>+</i> epidermal mucous cells and <i>pvalb8</i>-positive cells. by Yu-Fen Lu (171691)

Selective expansion of peritoneal cavity B1a cells in mice with targeted mutation of the <i>Siglecg</i> gene. by Cheng Ding (34937)

“…This experiment has been repeated 5 times involving a total of 10–12 mice per group. …”

Improving the measurement of TMS-assessed voluntary activation in the knee extensors by Jeanne Dekerle (800587)

“…In a fresh state, potentiated twitch force was unchanged following 1x5C but decreased following 2x5C (<i>P</i><0.05). …”

Structure of THC and its tautomeric structure. by Zhi Xuan Low (19270163)

“…Through the presence of an inclusion complex, a higher aqueous dispersion (65-fold) resulting in a higher drug content and an elevated release profile was achieved. …”

The spheroid assay is used to assess long-term effects of therapy on tumor cell by culturing the tumor cells in a micro-mass, which is a 3D tumor mass used as a surrogate for in vi... by Bryan S. Margulies (21492667)

“…<p>(A) MCF7 tumor cell micro-mass cultures (purple staining) treated with 0-, 1-, 2-, 2.5-, 5-, and 10-mM N-allyl noroxymorphone doses, after 336-hours, produced a significant decrease of 41.9% and 68.1% in micro-mass areas for the 5- and 10-mM N-allyl noroxymorphone concentrations, respectively (* = p < 0.014 and **** = p < 0.0001). …”

Epigenomic alteration of <i>Ink4a</i>-<i>Arf</i> locus. by Atsushi Kaneda (198186)

“…<i>p16</i> expression was partially increased in MEFp5, Mock and RasG12 due to stress-induced senescence during passages, but markedly increased in RasV12 cells. …”

DataSheet1_Analysis of Methylation Dynamics Reveals a Tissue-Specific, Age-Dependent Decline in 5-Methylcytosine Within the Genome of the Vertebrate Aging Model Nothobranchius furz... by Gordin Zupkovitz (10977372)

“…Data mining of the N. furzeri genome produced five dnmt gene family orthologues corresponding to the mammalian DNMTs (DNMT1, 2, 3A, and 3B). …”

Table_5_Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline.docx by Marta Cosín-Tomás (6066926)

“…SAMP8 mice presented 1,062 genes dysregulated at 2 months of age, and 1,033 genes at 9 months, with 92 genes concurrently dysregulated at both ages compared to age-matched SAMR1. SAMP8 mice showed a significant decrease in global DNA methylation (5-mC) at 2 months while hydroxymethylation (5-hmC) levels were increased in SAMP8 mice at 2 and 9 months of age compared to SAMR1. …”

Table_1_Integration of single-cell RNA sequencing and bulk RNA sequencing to reveal an immunogenic cell death-related 5-gene panel as a prognostic model for osteosarcoma.xlsx by Jiaqi Yang (4380466)

“…</p>Conclusions<p>Overall, ICD represented a protective factor against OS, and our 5-gene risk panel serving as a biomarker could effectively evaluate the prognostic risk in patients with OS.…”

Response of cell lines and primary marrow cells to DZNep and 5AZA. by Ekapun Karoopongse (630210)

“…<b>F</b>) Two different primary BM CD34+ cells specimens showing decreased H3K27m2 and H3K27m3, and decreased EZH2 protein expression upon combined treatment with Dznep+5AZA; Histone H3 served as nuclear loading control. …”

Long-term apoptosis-related protein expression in the diabetic mouse ovary by Nicolas A. Fraunhoffer (5728364)

“…The main objective of the present study was to analyze the apoptosis pathways activated during follicular loss at multiple time points in a diabetic mouse model. Twenty BALB/c mice were used in this study, and diabetes mellitus was induced by streptozotocin injection. …”

Guests’ Happiness in Luxury Hotels in Jordan: The Role of Spirituality and Religiosity in an Islamic Context by Koburtay, Tamer

Get full text
Get full text
Get full text

Effects of HP1a depletion on focal movement. by Raghuvar Dronamraju (204100)

“…The western blot shows a decrease in the level of HP1a, but not HP1b or -c. …”

HIF-1α is involved in the regulation of MUC5AC expression. by Yoon-Ju Kim (565859)

“…<p>When HIF-1α expression is increased, MUC5AC expression is induced; conversely, when HIF-1α expression is decreased, MUC5AC expression is reduced accordingly. …”

A J-Like Protein Influences Fatty Acid Composition of Chloroplast Lipids in Arabidopsis by Imad Ajjawi (200926)

“…T-DNA mutants in the poorly annotated <em>Arabidopsis thaliana</em> gene At1g08640 were identified as containing moderately high levels (50–100%) of 16∶1Δ7 and 18∶1Δ9 leaf fatty acids and subtle decreases (5–30%) of 16∶3 and 18∶3 (<a href="http://www.plastid.msu.edu/">http://www.plastid.msu.edu/</a>). …”

Antinociceptive and anti-inflammatory activities of a triterpene-rich fraction from Himatanthus drasticus by S.C.X. de-Almeida (6720584)

“…Indomethacin, used as reference, inhibited the paw edema by 59% at the same time-point. In the formalin test, FJNB inhibited the 1st phase by 27, 49, and 52% and the 2nd phase by 37, 50, and 67%, at the doses of 1, 5, and 10 mg/kg, respectively. …”

Severity of anaemia status among pregnant women. by Donatus Nbonibe Abaane (15909683)

“…At 28 weeks, AIP prevalence was 53.1% (95%CI:45.8, 60.3) and 37.5 (95%CI:30.6, 44.8) using a cut-off of 11.0g/dl and 10.5g/dl for those in the 2^nd trimester, respectively. …”