Delivery of Antisense Peptide Nucleic Acids to Cells by Conjugation with Small Arginine-Rich Cell-Penetrating Peptide (R/W)9 by Céline Cordier (616135)

“…To determine whether specificity of the interactions of arginines with cell surface proteoglycans result in the internalization, we used flow cytometry to examine uptake of arginine- and lysine-rich conjugates in wild-type CHO-K1 and proteoglycan-deficient A745 cells. The uptake of both conjugates was decreased by four fold in CHO-745 cells; therefore proteoglycans promote internalization of cationic peptides, irrespective of the chemical nature of their positive charges. …”

Effect of adenylate cyclase (AC) agonist or antagonist on <i>I</i>_SC induced by FA. by Yu-Li Luo (276276)

“…(B) Pretreatment with the AC antagonist MDL-12330A (10 µM) to the basolateral side decreased FA-induced <i>I</i>_SC. …”

Data_Sheet_1_Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppress... by Thorsten R. Doeppner (4020179)

“…Mice undergoing rPostC underwent three different paradigms, starting with the first cycle of rPostC 12 h, 24 h, or 5 days after stroke induction, which is a very delayed time point of rPostC that has not been studied elsewhere. rPostC as applied within 24 h post-stroke induces reduction of infarct volume on day three. …”

Data_Sheet_2_Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppress... by Thorsten R. Doeppner (4020179)

“…Mice undergoing rPostC underwent three different paradigms, starting with the first cycle of rPostC 12 h, 24 h, or 5 days after stroke induction, which is a very delayed time point of rPostC that has not been studied elsewhere. rPostC as applied within 24 h post-stroke induces reduction of infarct volume on day three. …”

Evidence from cell culture retrotransposition assays that MOV10 inhibits insertion of non-LTR retrotransposons. by John L. Goodier (126693)

“…<p>(A) The reporter construct 99 PUR RPS EGFP was cotransfected in 293T cells with empty vector (pcDNA3) or constructs expressing V5-MOV10 or other epitope-tagged L1 RNP-associated helicases. …”

Increased Fhl1b activity suppresses specification of pancreatic cells and induces liver. by Jin Xu (31283)

“…The number of <i>Tg(ptf1a</i>:GFP<i>)</i>^<i>jh1</i>-expressing cells decreased from 82.2±6.4 in control embryos to 16.0±5.2 in <i>fhl1b-</i>overexpressing embryos (heat shock applied at the 8-somite stage). …”

Voltage traces and two-dimensional phase-space representations for the NAS-SC model for increasing values of <b>.</b> by Tilman Kispersky (238356)

“…Increasing values of cause a progressive decrease in the influence of the slow manifold on the trajectory and thus no rapid transitions in firing rate are observed.…”

Inhibition of mitochondrial function by BBR in hepatocytes. by Xuan Xia (356454)

“…<p>(A) BBR decreased oxygen consumption in H4IIE hepatocytes. …”

Changes in the expression of <i>deadpan</i> by LOF and GOF of <i>pros</i>. by Jordi Colonques (222976)

“…Notice that many large DPN+ CB NBs (arrowheads) are missing in the <i>c831Gal4;UAS-pros</i> lobe which also shows an important decrease in DPN+ cells in the OPC. C,E. Single confocal images taken, as indicated in the framed areas of A and B, at a medial level of the most anterior part of the OPC. …”

Image_1_Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.TIF by Yun Huang (169805)

“…Polycyclic aromatic hydrocarbons (PAHs), a group of environmental pollutants that are reported as a risk factor of NTDs, may cause decreased genome-wide DNA methylation. …”

Data_Sheet_1_Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.docx by Yun Huang (169805)

“…Polycyclic aromatic hydrocarbons (PAHs), a group of environmental pollutants that are reported as a risk factor of NTDs, may cause decreased genome-wide DNA methylation. …”

Image_4_Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.TIF by Yun Huang (169805)

“…Polycyclic aromatic hydrocarbons (PAHs), a group of environmental pollutants that are reported as a risk factor of NTDs, may cause decreased genome-wide DNA methylation. …”

Image_2_Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.PNG by Yun Huang (169805)

“…Polycyclic aromatic hydrocarbons (PAHs), a group of environmental pollutants that are reported as a risk factor of NTDs, may cause decreased genome-wide DNA methylation. …”

Image_3_Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure.TIF by Yun Huang (169805)

“…Polycyclic aromatic hydrocarbons (PAHs), a group of environmental pollutants that are reported as a risk factor of NTDs, may cause decreased genome-wide DNA methylation. …”

DataSheet_1_Chromatin dynamics associated with seed desiccation tolerance/sensitivity at early germination in Medicago truncatula.xlsx by Naoto Sano (12846914)

“…The seed DT is lost at early post germination stage but is temporally re-inducible in 1 mm radicles during the so-called DT window following a PEG treatment before being permanently silenced in 5 mm radicles of germinating seeds. …”

Image_1_Chromatin dynamics associated with seed desiccation tolerance/sensitivity at early germination in Medicago truncatula.tif by Naoto Sano (12846914)

“…The seed DT is lost at early post germination stage but is temporally re-inducible in 1 mm radicles during the so-called DT window following a PEG treatment before being permanently silenced in 5 mm radicles of germinating seeds. …”

Image_2_Chromatin dynamics associated with seed desiccation tolerance/sensitivity at early germination in Medicago truncatula.tif by Naoto Sano (12846914)

“…The seed DT is lost at early post germination stage but is temporally re-inducible in 1 mm radicles during the so-called DT window following a PEG treatment before being permanently silenced in 5 mm radicles of germinating seeds. …”

QC, including cluster size thresholding and declumping, improves precision, sometimes at the expense of recall, for images with lower SNR values. by Jenny M. Vo-Phamhi (11250803)

“…<b>(C)</b> Thresholding clusters by the number of annotations in the cluster and by the fraction of unique workers who contribute multiple times to the cluster improved recall by 17%, while decreasing precision by 11% on average, in an experiment with nine images with 50, 100, and 150 spots; mean SNR = 5, 10, and 15; and average nearest neighbor distance (NND) ≈ 11.5, 15, and 20.5.…”

Host cytosolic calcium increases prior to PV rupture. by My-Hang Huynh (20360)

“…A vertical line denotes the time point after which host Ca²⁺ levels increase and when the PV pH decreases. …”

Complementary conditioning measures across the clinical study groups. by Gabriela Ribeiro (4748373)

“…CS⁺ (F_{(1, 50)} = 5.2, <i>P</i> = 0.03), with a no significant effects for Group (F_{(2, 50)} = 0.1, <i>P</i> = 0.9) nor for interaction (F_{(2, 50)} = 0.9, <i>P</i> = 0.4). …”