Blocking PI3K/Akt signaling by RNAi or inhibitors enhances HB9 mRNA expression in hNSCs. by Luis Ojeda (208583)

“…<p>(A) Effect of PI3K knockdown on HB9 expression in hNSCs. …”

Vascular smooth muscle cells inhibit endothelial cell proliferation and drive Rac1-dependent morphogenesis. by Lasse Evensen (263932)

“…(B) In constrast, co-cultured GFP-expressing HUVEC do not incorporate BrdU, while PA-vSMC SMC divides until confluency. (C) Flow-cytometry analysis showed that HUVEC cells in co-culture have a 4.4-fold decreased proliferation activity compared to a HUVEC mono-culture. …”

Bufalin exerted potent anti-osteosarcoma activity <i>in vitro</i>. by Xian-biao Xie (302694)

“…<p>(A) Bufalin induced a dose- and time-dependent decrease in osteosarcoma cell growth. …”

SEAwise report on improved predictive models of recruitment under different environmental scenarios by Paco Melià (162862)

“…Hake spawning stock biomass has a positive effect on recruitment up to a certain stock size but recruitment decreases at larger stock sizes. …”

The downregulation of Chk-α attenuated the phosphorylation levels of ERK1/2, AKT and mTOR. by Hoe Suk Kim (107279)

“…Data are presented as the mean ± standard deviation of 5 independent experiments. …”

Temperature and precipitation change during 1951–2002. by Evan H. Girvetz (256065)

“…<p>Maps of the magnitude (left) and confidence (right) for annual mean temperature (top) and precipitation trends during 1951–2002 for each 0.5 degree grid cell in the CRU TS 2.1 data set <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008320#pone.0008320-Mitchell1" target="_blank">[10]</a>. …”

Robustness of topological invariants to noise. by Robert Clark Penner (220064)

“…<p>Left: Scatter plots of and for domains in CATH topology <i>Pectate Lyase C-like</i> (2.160.20). The five H-levels are indicated by different colors ( to domains in size), and a clear separation of H-levels is observed. …”

IL-10^−/− mice demonstrate significantly reduced retinal neovascularization in response to ischemia. by Dru S. Dace (259377)

“…Fluorescent microscopy of perfused retinas of (A) normoxic-treated wild-type mice (n = 5), (B) oxygen-treated wild-type mice (n = 5), and (C) oxygen-treated IL-10^−/− mice (n = 4) reveal decreased angiogenesis and increased areas of non-perfusion in IL-10^−/− mice. …”

FoxO1 deacetylation couples Sirt1 action to POMC expression. by Işin Çakir (256194)

“…<p><i>(A)</i> Representative western blots showing the acetylation status of FoxO1 and Stat3 upon fasting and intraperitoneal leptin administration. 5 animals per group were evaluated. …”

Insulin secretion and mRNA assay in MIN6 cells after infection with equivalent titer of adenovirus. by Weina Gao (537908)

“…(A) MIN6 cells were treated with 0.5 µM thapsigargin (TG) or DMSO (vehicle control) for 1 h, 0.5 mM palmitate (PA) or 0.5% BSA (vehicle control) for 12 h, and the supernatants were assayed for insulin protein level (n = 3). …”

Effect of Ang II and Zol on EPC <i>in vitro</i> tube formation ability. by Jin-Xiu Yang (128753)

“…B: Light micrographs showing typical tubules (200×). <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046511#s3" target="_blank">Results</a> are the mean ± SD, n = 5. …”

<i>Tcf21</i> promoter mutagenesis analysis. by Ramji K. Bhandari (136008)

“…Bars with asterisks are significantly different from −0.5 kb control promoter. (B) Promoter activity decreased with the length of the promoter. …”

Deviation from the original expression profiles after probe filtering by Kyu-Baek Hwang (5187)

“…The mean correlation coefficient decreases as the minimum overlapping length increases. …”

S1 Data - by Jira Wakoya Feyisa (9607032)

“…The current meta-analysis revealed that average monthly income <1800 ETB (OR = 2.66, 95% CI 1.44, 4.90) lack of ANC follow-up (OR = 2.57, 95%CI 1.32, 5.01), being multipara (OR = 1.77, 95%CI 1.39, 2.25), poor knowledge about obstetric danger sign (OR = 5.75, 95%CI 1.o2, 32.42), and not discussing the place of delivery with a partner (OR = 5.89 (95%CI 1.1, 31.63) were significantly associated with homebirth preference.…”

The functional effects of three novel human isoforms, GABAB1k, l, and m. by Changhoon Lee (360362)

“…After one-way ANOVA and Dunnett's tests, one-tailed unpaired Student's t-tests were performed between no isoform injected groups and the isoform injected groups. A. GABAB1k had no inhibitory effect. B. GABAB1l data showed significant differences by ANOVA and Dunnett's tests (p = 0.0058), and caused significantly decreased GIRK currents at 5× and 6× GABAB1l (**p = 0.0014 and *p = 0.0229, respectively). …”

Comparison between observation and predicted microbial composition in the cecum. by Richard R. Stein (496395)

“…(D) Rank correlation of measured with predicted data points. Colors indicate elapsed time. 75% confidence ellipses are drawn for the first (blue) and last (red) predicted time points.…”

Memory effect on effective memory lifetime. by Katherine Daftari (20910118)

“…<p>(A) The average mutual information as a function of delay time decreases as the value of <i>μ</i> increases and the self-avoidant memory response is suppressed. …”

Data_Sheet_1_Combined Carbon and Albedo Climate Forcing From Pine and Switchgrass Grown for Bioenergy.pdf by Benjamin J. Ahlswede (12539725)

“…We found that pine had a net positive radiative forcing (warming) of 5.4 ± 2.8 Wm⁻² when albedo and carbon were combined together (30 year mean). …”

PDGFRA surface expression is down-regulated by MEK inhibitor U0126. by Dongfeng Chen (405191)

“…MEK inhibitor U0126 decreased PDGFRA surface expression detected by FACS in cell line #2. …”

Measurement of lysosome proteolytic and acidic functions in response to PIKfyve inhibition and ROS. by Golam T. Saffi (11747438)

“…(D) RAW cells treated with vehicle or 20 nM apilimod for 40 min alone, or in combination with 1 μM rotenone for 60 min or 1 mM H₂O₂ for 40 min, and stained for LysoTracker Red as an indicator of lysosome acidification. Scale bar: 5 μm. (E) Quantification of mean lysotracker intensity per cell normalized to control cells. …”