Image_1_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.TIF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Image_4_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.TIF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Data_Sheet_3_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.PDF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Data_Sheet_2_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.PDF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Image_3_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.TIF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Image_2_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.TIF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Data_Sheet_1_Human Motor Neurons With SOD1-G93A Mutation Generated From CRISPR/Cas9 Gene-Edited iPSCs Develop Pathological Features of Amyotrophic Lateral Sclerosis.PDF by Byung Woo Kim (9658103)

“…Here, using CRISPR/Cas9 genome editing system and human induced pluripotent stem cells (iPSCs), we generated highly pure, iPSC-derived MNs with a SOD1-G93A missense mutation. With the wild-type cell line serving as an isogenic control and MNs from a patient-derived iPSC line with an SOD1-A4V mutation as a comparator, we identified pathological phenotypes relevant to ALS. …”

Table_1_Mild-Intensity UV-A Radiation Applied Over a Long Duration Can Improve the Growth and Phenolic Contents of Sweet Basil.pdf by Seonghwan Kang (12428847)

“…The maximum quantum efficiency of photosystem II (PSII) for photochemistry (F_v/F_m) showed a gradual decrease under the 20 and 30 W·m⁻² treatments from 3 to 14 DAT, whereas F_v/F_m remained relatively constant under the 0 and 10 W·m⁻² treatments over the entire 14 days. …”

Table_2_Mild-Intensity UV-A Radiation Applied Over a Long Duration Can Improve the Growth and Phenolic Contents of Sweet Basil.pdf by Seonghwan Kang (12428847)

“…The maximum quantum efficiency of photosystem II (PSII) for photochemistry (F_v/F_m) showed a gradual decrease under the 20 and 30 W·m⁻² treatments from 3 to 14 DAT, whereas F_v/F_m remained relatively constant under the 0 and 10 W·m⁻² treatments over the entire 14 days. …”

Fig 7 - by Saeed El-Ashram (710370)

METTL3 alleviates renal tubular mitochondrial dysfunction by regulating the TUG1/PGC-1a axis in an IGF2BP2-dependent manner in diabetic nephropathy by Tong Chen (188814)

Biologically-based modeling of radiation risk and biomarker prevalence for papillary thyroid cancer in Japanese a-bomb survivors 1958–2005 by Jan Christian Kaiser (8813705)

Trend in PPI and H₂RA uses from 2010 to 2019 in Japan. by Nobutake Yamamichi (381131)

Fig 6 - by Lachlan D. Barnes (13783099)

“…We used high-, medium-, and low-intensity noise: SNR = 5, 10, and 20, respectively (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0272167#sec002" target="_blank">Methods</a>). …”

Comparison between TLC and HPLC used in this study. by Jae Kyo Yi (13570063)

Suggested ACER3 catalytic mechanism. by Jae Kyo Yi (13570063)

Data_Sheet_5_Transcriptomic and physiological analysis reveals the possible mechanism of ultrasound inhibiting strawberry (Fragaria × ananassa Duch.) postharvest softening.xlsx by Junyi Zhang (290426)

Schematic representation of tumor kinetics study in diabetic and non-diabetic mice. by Vidya G. Bettada (22208808)

Epidemic curves and mobility change stratified by neighborhood-level income and essential worker quintiles in the Greater Toronto Area, Canada (February 23, 2020 to December 13, 20... by Siyi Wang (1412581)

Vimentin staining of placentas, indicating the endothelial cells. by Solange N. Eloundou (6551627)