microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects by Kang He (189002)

“…<p>The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…Cells of the ventricular and subventricular zones of the cortex show strongest decrease in staining intensity (black arrowhead). Scale bar equals 400 µm; ctx, cortex; th, thalamus; cpt, caudoputamen; cp, cortical plate; iz, intermediate zone; svz, subventricular zone; vz, ventricular zone; sn, septal nuclei; 3v, third ventricle; lv, lateral ventricle; pc, choroid plexus.…”

Local Infusion of Insulin Restores AMPH-Evoked DA Release in Striatum of STZ-Treated Rats by Jason M Williams (61649)

“…<p>Summary data for HSCA (<i>n</i> = 5–7). When measured in the dorsal striatum and compared to saline-treated control subjects, STZ-induced depletion of insulin (STZ) resulted in a significant reduction in the rate of DA efflux in response to local injection of AMPH (400 μM/125 nl; (A) as well as a decrease in the maximum amount of released DA (B) and the rate of DA clearance (C) with respect to control. …”

<i>mecR2</i> is essential for the optimal expression of β-lactam resistance in strains with functional <i>mecI-mecR1</i> regulatory locus. by Pedro Arêde (149569)

“…Note that film was exposed for 4 h whereas in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002816#ppat-1002816-g005" target="_blank">Figure 5A</a> it was exposed for 48 h.…”

Functional capacity and mental state of patients undergoing cardiac surgery by Bruna Corrêa (4586776)

“…Results: This study assessed nine patients (eight males) aged 62.4 ± 6.3 years with a BMI of 29.5 ± 2.3 kg/m2. There was a significant decrease in DASI scores and VO2 from preoperative to postoperative status (p = 0.003 and p = 0.003, respectively). …”

Changes in Membrane Plasmalogens of <i>Clostridium pasteurianum</i> during Butanol Fermentation as Determined by Lipidomic Analysis by Jan Kolek (712011)

“…When butanol is produced by bacterial cells, then the cells are not subjected to severe stress and responded to it by relatively slowly changing the content of fatty acids and plasmalogens, while after a pulse addition of external butanol (to a final non-lethal concentration of 0.5 % v/v) the cells reacted relatively quickly (within a time span of tens of minutes) by increasing the total plasmalogen content.…”

Association analysis, given linkage, conditional on the top SNP. by Rohina Rubicz (104167)

“…The regression coefficients refer to the estimated change in the phenotype for each dose of the rarer SNP allele.</p>a<p>Since we used a liability threshold model for analysis of the dichotomous trait (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003147#s4" target="_blank">methods</a> section), the direction of effect on EBNA-1 discrete serostatus is opposite of the sign of the regression coefficient, but is in the same direction as the regression coefficient for the quantitative trait (e.g. for SNP rs204999, the minor allele is associated with a decrease in EBNA-1 antibody level and seronegativity).…”

The SMART Randomised Controlled Trial by Henrietta Graham (17017581)

“…A small change approach may therefore be an appropriate strategy to reduce the 0.5 to 1 kg of average adult weight gain seen each year and may lead to decreased prevalence of overweight and obesity over time. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Human MADD fibroblast cells display similar mitochondrial defects as <i>xav</i> mutants. by Yuanquan Song (238595)

“…The expression of ROS related genes are also altered in Patient 1, with a ca. 20% decrease in <i>catalase</i> and 4.7 and 5.7 fold increase in <i>glutathione reductase</i> and <i>HSPA9</i> expression (N = 3–7 replicates of cells from passage 7–12; Student's t test, * p<0.05, ** p<0.01, *** p<0.001).…”

Supplementary Material for: Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing’s Disease by Castillo V. (4126174)

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory and antiproliferative signaling cascades. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Table 1_Impact of donor transaminases on liver transplant utilisation and unnecessary organ discard: national registry cohort study.docx by Joseph J. Dobbins (19536196)

“…AST was also a significant predictor of liver decline. 18.5% of livers from DBD donors with ALT > 40 U/L (n = 1,683) were declined for transplantation. …”

Outcomes of the two-layer model determined by the MCMC fitting to the pulse and prolonged protocols. by Laurent Mackay (4248592)

“…The bath medium had Na⁺ replaced by NMDG⁺ modeled by setting <i>E</i>₁ = −93.5 mV and <i>E</i>₂ = −5.1 mV. Voltage was ramped from − 80 mV to + 80 mV twice per second from a holding potential of − 60 mV. …”

Mitochondrial Complex IV Remodeling after miR-181c Treatment. by Samarjit Das (561679)

“…(D) Western blot shows the changes of other isoforms of mitochondrial respiratory chain complex IV. We have observed a significant decrease in the protein content of COX VIIa in the miR-181c overexpression groups, but no effect on COX 5A and COX 5B. α-tubulin was used as the loading control. …”

Table_1_Prevalence and WGS-based characteristics of MRSA isolates in hospitals in Shanghai, China.XLS by Hongzhi Zhang (425117)

“…<p>Methicillin-resistant Staphylococcus aureus (MRSA) isolates remain a serious threat to global health despite a decrease in MRSA infections since 2005. …”

The influence of health policy on early diagnosis and surgical incidence of developmental dysplasia of the hip by Chia H. Chang (5571032)

“…The results suggest that the health promotion policy is associated with an increase in early diagnosis and subsequently a decrease in surgeries for DDH.</p></div>…”

Risk factors for mortality of children with zoonotic visceral leishmaniasis in Central Tunisia by Khaled Ben Helel (4726218)

“…The risk factors for in-hospital death identified by a multivariate analysis were: bleeding at admission (OR = 25.5, 95% CI: 2.26–287.4; p = 0.009), white cell count less than 4000/mm3 (OR = 5.66, 95% CI: 1.16–27.6; p = 0.032), cytolysis (OR = 28.13, 95% CI: 4.55–173.6; p < 0.001), and delay between onset of symptoms and admission ≥ 15 days (OR = 11, 95% CI: 1.68–72; p = 0.012).…”

Length and GC Content Variability of Introns among Teleostean Genomes in the Light of the Metabolic Rate Hypothesis by Ankita Chaurasia (610453)

“…<div><p>A comparative analysis of five teleostean genomes, namely zebrafish, medaka, three-spine stickleback, fugu and pufferfish was performed with the aim to highlight the nature of the forces driving both length and base composition of introns (i.e., bpi and GCi). …”

Shed GP induces secretion of cytokines from DCs and MØ. by Beatriz Escudero-Pérez (663743)

“…<p>(<b>A</b>) 5×10⁵ of DCs (in white) and MØ (in gray) were incubated for 24 h with concentrated culture supernatants as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004509#ppat-1004509-g002" target="_blank">Figure 2</a>. …”