Immediate Changes in Peripapillary Retinal Vasculature after Intraocular Pressure Elevation -an Optical Coherence Tomography Angiography Study by Xiaolei Wang (139592)

“…</p> <p><b>Conclusions</b>: LPI-induced IOP spikes resulted in a decrease in retina vessel density with PACS eyes by OCTA. …”

Data_Sheet_1_Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppress... by Thorsten R. Doeppner (4020179)

“…Mice undergoing rPostC underwent three different paradigms, starting with the first cycle of rPostC 12 h, 24 h, or 5 days after stroke induction, which is a very delayed time point of rPostC that has not been studied elsewhere. rPostC as applied within 24 h post-stroke induces reduction of infarct volume on day three. …”

Data_Sheet_2_Very Delayed Remote Ischemic Post-conditioning Induces Sustained Neurological Recovery by Mechanisms Involving Enhanced Angioneurogenesis and Peripheral Immunosuppress... by Thorsten R. Doeppner (4020179)

“…Mice undergoing rPostC underwent three different paradigms, starting with the first cycle of rPostC 12 h, 24 h, or 5 days after stroke induction, which is a very delayed time point of rPostC that has not been studied elsewhere. rPostC as applied within 24 h post-stroke induces reduction of infarct volume on day three. …”

<i>FoxD(RNAi)</i> animals display abnormal anterior pole, head patterning and midline gene expression. by M. Lucila Scimone (508003)

“…<p>(<b>A</b>) Upper panels: animals injected with <i>FoxD</i> dsRNA regenerated normally sized anterior blastemas with one eye (73/130) or smaller blastemas with no eyes (24/130) seven days following amputation. …”

Relationship between loneliness and time out-of-home. by Johanna Petersen (803541)

“…As can be seen, the average amount of time spent outside the home given a participant leaves the home decreases from 5.0 hours at a UCLA Loneliness score of 21 (the lowest observed) to 3.7 hours at a UCLA Loneliness score of 56 (the highest observed). b) Probability of leaving the home on a given day as a function of the UCLA Loneliness score. …”

Table_3_Ultramicronized N-Palmitoylethanolamine Supplementation for Long-Lasting, Low-Dosed Morphine Antinociception.DOC by Lorenzo Di Cesare Mannelli (600627)

“…The same pain threshold increase was achieved in animals using preemptive PEA (30 mg/kg, daily) joined to a combinatorial acute treatment with morphine (5–20 mg/kg s.c.) and PEA (30–120 mg/kg, p.o.). …”

Data Sheet 1_Activation of the Nrf2/HO-1 pathway restores N-acetylcysteine-induced impairment of the hypothalamus-pituitary-adrenal axis negative feedback by up-regulating GRα expr... by Amanda Silva Chaves (20466374)

“…Furthermore, NAC induced adrenal enlargement and hypercorticoidism, along with a decrease in the GRα expression and an increase of GRβ expression in the pituitary gland. …”

Supplementary Material for: Peridialytic Erythropoietin versus Roxadustat in Hemodialysis-dependent CKD Patients by figshare admin karger (2628495)

“…A propensity score-matched analysis (1:1 ratio; caliper width: 0.02) was conducted to minimize the impact of confounding factors. …”

Image1_The involvement of the noradrenergic system in the antinociceptive effect of cucurbitacin D on mice with paclitaxel-induced neuropathic pain.jpeg by Keun-Tae Park (14326092)

“…The cucurbitacin D dose-dependently (0.025, 0.1, and 0.5 mg/kg) attenuated both allodynia types. In the spinal cord, paclitaxel injection increased the gene expression of noradrenergic (α₁-and α₂-adrenergic) receptors but not serotonergic (5-HT_1A and ₃) receptors. …”

Image1_Morphological, electrophysiological, and molecular alterations in foetal noncompacted cardiomyopathy induced by disruption of ROCK signalling.TIF by David Sedmera (636625)

“…The cause of the early noncompaction at E15.5 was attributed to a decrease in proliferation in the developing ventricular wall. …”

Influence of the main stem pruning and fruit thinning on quality of melon by Rafaella Martins de Araújo Ferreira (12689661)

“…In Amaregal melon, fruits showed longer length (134 mm) and greater flesh firmness (40 N) when thinning was carried out on 6 DARB, and as thinning was delayed, it found a decrease in the values of soluble solids, SS: TA ratio and pH. …”

Spatial Frequency Discrimination: Effects of Age, Reward, and Practice by Carlijn van den Boomen (3079293)

“…In both reward conditions children aged 5–6 years completed only a fourth or half of the run (64 to 128 out of 254 trials) and were not motivated to continue. …”

Altering Pyrroloquinoline Quinone Nutritional Status Modulates Mitochondrial, Lipid, and Energy Metabolism in Rats by Kathryn Bauerly (213012)

“…Moreover, PQQ administration (i.p. at 4.5 mg/kg BW for 3 days) resulted in a greater than 2-fold decrease in plasma triglycerides during a 6-hour fast than saline administration in a rat model of type 2 diabetes. …”

Diet-induced remodeling of liver mitochondria protein acetylation and succinylation. by Jesse G. Meyer (6156995)

“…Groups of boxed sites denote the sets used for functional analysis in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0208973#pone.0208973.g005" target="_blank">Fig 5</a>. …”

DataSheet_1_Crosstalk Between Pyroptosis and Apoptosis in Hepatitis C Virus-induced Cell Death.pdf by Hannah L. Wallace (12082871)

“…The purpose of this study was to investigate the mechanism of HCV-induced cell death and to determine the timing and relative contributions of apoptosis and pyroptosis during HCV infection. In a model employing a cell culture-adapted strain of JFH-1 HCV and Huh-7.5 hepatocyte-like cells, we found that pyroptosis occurred earlier than did apoptosis during infection. …”

Data_Sheet_1_SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway.doc by Xiao-Ning Li (2008540)

“…In this study, we show that SWL-1 reverses resistance to fluconazole in C. albicans when delivered in combination, with a sharp decrease in the IC₅₀ of fluconazole from >200 to 3.74 ± 0.25 μg/ml, and also reverses the fluconazole resistance of C. albicans in vitro, with IC₅₀ from >200 to 5.3 ± 0.3 μg/ml. …”

Transwell migration assay: hDPSC significantly induced the migration of the endothelial cells HMEC-1. by Annelies Bronckaers (442675)

“…Both LY294002 and U0126, were able to significantly decrease the hDPSC-induced HMEC-1 migration at a concentration of 10 µM. …”

Supplementary Material for: Airway Hyperresponsiveness Is Negatively Associated with Obesity or Overweight Status in Patients with Asthma by Kwon J.-W. (4131307)

“…The intensity of AHR was assessed by the concentration of methacholine needed to cause a 20% decrease in FEV₁ (PC₂₀). …”

Supplementary Material for: Personalized Approach of Severe Eosinophilic Asthma Patients Treated with Mepolizumab and Benralizumab by Bergantini L. (9186272)

“…<b><i>Materials and Methods:</i></b> A cohort of 28 patients affected by severe eosinophilic asthma were treated with anti-IL-5 drugs. …”

Table_2_Ultramicronized N-Palmitoylethanolamine Supplementation for Long-Lasting, Low-Dosed Morphine Antinociception.doc by Lorenzo Di Cesare Mannelli (600627)

“…The same pain threshold increase was achieved in animals using preemptive PEA (30 mg/kg, daily) joined to a combinatorial acute treatment with morphine (5–20 mg/kg s.c.) and PEA (30–120 mg/kg, p.o.). …”