Heat map grid summarizing the effects of LPS, (+)-JQ and (-)-JQ1 on histone 3 acetylation at the promoters of <i>IL6</i>, <i>CXCL8/IL8</i>, <i>TNF</i>, <i>IL10</i> and <i>IDO1</i>. by Sandeep Ajgaonkar (14774336)

“…The significance threshold is 5% FDR (Q<0.05), highlighted in bold. The orange color indicates a significant increase, the blue color indicates a significant decrease in the acH3 ChIP signal regarding the contrasts shown. …”

Data_Sheet_1_Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health.docx by Bob T. Rosier (2601973)

“…When adding nitrate (prebiotic treatment) or isolates in combination with nitrate (symbiotic treatment), a smaller decrease in pH derived from sugar metabolism was observed (p < 0.05), which for some symbiotic combinations appeared to be due to lactate consumption. …”

Image_1_Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health.TIF by Bob T. Rosier (2601973)

“…When adding nitrate (prebiotic treatment) or isolates in combination with nitrate (symbiotic treatment), a smaller decrease in pH derived from sugar metabolism was observed (p < 0.05), which for some symbiotic combinations appeared to be due to lactate consumption. …”

Non-linear growth in tree ferns, <i>Dicksonia antarctica</i> and <i>Cyathea australis</i> by David P. Blair (4020062)

“…In this study, we measured 5 years of growth of <i>Cyathea australis</i> and <i>Dicksonia antarctica</i> after a large wildfire in 2009 in south-eastern Australia. …”

Table_1_Phytosulfokine alpha enhances regeneration of transformed and untransformed protoplasts of Brassica oleracea.pdf by Valentin Vogrinčič (17968460)

“…The PSK-α showed a strong stimulatory effect on untransformed protoplast regeneration already during the first days of culture, accelerating cell division up to 5.3-fold and the formation of multicellular microcallus colonies up to 37.0-fold. …”

Data_Sheet_1_Nitrogen Use Efficiency, Allocation, and Remobilization in Apple Trees: Uptake Is Optimized With Pre-harvest N Supply.docx by Bi Zheng Tan (10898982)

“…Subsequent spring remobilization of NDF was not affected by the timing of N fertigation from the previous season. A seasonal effect of remobilization was observed with a decrease in root N status and a reciprocal increase in branch N status at fruit harvest of season two. …”

Anti-tumor effects of DEspR-inhibition in Panc1-CSC xenograft tumors in nude rats. by Victoria L. Herrera (383897)

“…(E) Representative images of tumor expanding zones with identical exposure settings depict robust differences in key histopathological parameters pertinent to efficacy determinations in Panels A, C and D between non-treated control (Non-treated) and anti-DEspR mAb treated (Treated) nude rat subcutaneous Panc1-CSC xenograft tumors: 1) cellularity (H&E: Cell Density, 2) mitotic index (Masson Trichrome MT: mitotic profile), 3) extent of tumor invasiveness to adjacent normal tissue (MT: invasiveness), and 4) human-specific CD31+ and human-specific 7c5b2 DEspR+ fluorescent immunostaining of microvessels and adjacent tumor cells (IF: microvascularity). …”

Roflumilast-Mediated Phosphodiesterase 4D Inhibition Reverses Diabetes-Associated Cardiac Dysfunction and Remodeling: Effects Beyond Glucose Lowering by Rui Xu (158313)

“…Mice on HFD developed diabetes and cardiac dysfunction with increased cardiac PDE4D5 expression. PDE4 inhibitor roflumilast can reverse hyperglycemia and cardiac dysfunction, accompanied by the decrease of PDE4D expression and increase of muscle-specific microRNA miR-1 level in hearts. …”

Table_1_Feeding Faba Beans (Vicia faba L.) Reduces Myocyte Metabolic Activity in Grass Carp (Ctenopharyngodon idellus).DOCX by Jing-jing Tian (778123)

“…<p>In this study, we aimed to explore the effects of faba bean (Vicia faba L.) on the energy metabolism of grass carp (Ctenopharyngodon idellus). A total of 180 fish (∼2900 g) were randomly assigned to six tanks (2.5 × 2.5 × 1.2 m; 30 individuals per tank) and fed either faba bean (Vicia faba L.) or a commercial diet for 120 days (3% body weight, twice per day). …”

Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia by Olivier Cases (760028)

“…Immunomorphological and ultrastructural analyses showed that increased eye lengthening was first observed by post-natal day 5 (P5) and that it was accompanied by a rapid decrease of the bipolar, photoreceptor and retinal ganglion cells, and eventually the optic nerve axons. …”

Table_1_Feeding Faba Beans (Vicia faba L.) Reduces Myocyte Metabolic Activity in Grass Carp (Ctenopharyngodon idellus).DOCX by Jing-jing Tian (778123)

“…<p>In this study, we aimed to explore the effects of faba bean (Vicia faba L.) on the energy metabolism of grass carp (Ctenopharyngodon idellus). A total of 180 fish (∼2900 g) were randomly assigned to six tanks (2.5 × 2.5 × 1.2 m; 30 individuals per tank) and fed either faba bean (Vicia faba L.) or a commercial diet for 120 days (3% body weight, twice per day). …”

Data_Sheet_1_Assessment of Climate Change Impacts on Chilling and Forcing for the Main Fresh Fruit Regions in Portugal.PDF by Helder Fraga (633694)

“…Future projections show a clear decrease in chilling for all regions and fruit types in Portugal. …”

Data_Sheet_3_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Housing and road transport modify the brain neurotransmitter systems of pigs: Do pigs raised in different conditions cope differently with unknown environments? by Laura Arroyo (3422744)

“…After one month, one set of animals from each housing condition were driven in a truck to the slaughterhouse in low-stress conditions (5 min drive, no mixing groups, soft management, LS group, n = 12) or high-stress conditions (2 hours drive, mixing groups, harsh management, HS group, n = 12). …”

Data_Sheet_1_Preparation of nano-selenium from chestnut polysaccharide and characterization of its antioxidant activity.docx by Shanshan Wang (283009)

“…The DPPH free radical scavenging rate of purified polysaccharide fraction CP-1a was slightly enhanced, and the other rates showed a small decrease. …”

HCMV triggers cell proliferation via IL-6-STAT3 activation in HepG2 cells and PHH. by Quentin Lepiller (394353)

“…(C) Increased cell proliferation in HepG2 cells infected with AD169 is blocked by a neutralizing anti-IL-6R mAb (10 microg/ml), a Jak inhibitor (1 micromol/l) and a STAT3 inhibitor (10 micromol/l), and decreased cell proliferation was observed in HepG2 cells infected with UV-inactivated HCMV. …”

zVADfmk and zLLYfmk reduced the level of apoptosis during ex vivo expansion. by Sangeetha V. M (243677)

“…Data represented as mean positive population ± standard deviation from five independent experiments n = 5 (B) The presence of active caspases (Casp3/7) in the culture was assessed using a cell free cytosolic enzymatic assay and the zVADfmk/zLLYfmk sets showed a significant reduction in the activity of these caspases as assessed from four different CB units. …”

Spatially Defined InsP₃-Mediated Signaling in Embryonic Stem Cell-Derived Cardiomyocytes by Nidhi Kapoor (290320)

“…Buffering of InsP₃ by FIRE-1nuc had no effect on the basal frequency while attenuation of InsP₃ signaling throughout the cell (FIRE-1), or at the plasma membrane (m43) resulted in a 53.7% and 54.0% decrease in beating frequency. …”

RHO-1 regulates brood size. by Rachel McMullan (183027)

“…Expression of activated <i>hsRHO-1</i>(<i>G14V</i>) (<i>nzIs1</i>) or <i>hsC3 transferase</i> (<i>nzEx4</i>) resulted in a decrease in brood size.…”

Effect of <i>OPA1</i> or <i>Mfn1</i> silencing on mitochondrial Ca²⁺ uptake in permeabilized HeLa cells. by László Fülöp (203208)

“…<p>For the transfection protocol and measurement of fluorescence see legend of <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025199#pone-0025199-g005" target="_blank">Figure 5</a>. …”