DataSheet2_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

Image1_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.TIFF by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

Table1_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.DOCX by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

DataSheet1_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

DataSheet6_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

DataSheet7_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

DataSheet3_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.ZIP by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

Table2_Yi-Shen-Hua-Shi granules inhibit diabetic nephropathy by ameliorating podocyte injury induced by macrophage-derived exosomes.DOCX by Mingzhu Liang (11011660)

“…Compared with the exosomes secreted by macrophages after an HG treatment, the exosome from macrophages treated with HG and YSHS granule showed lower inhibitory effects on podocyte activity, accompanied by the decreased upregulating effects of macrophage-derived exosomes on the miR-21a-5p in podocytes. miR-21a-5p mimics could reduce podocyte activity and promote caspase-3 shearing. …”

Kinetic and equilibrium constants for binding of WT and mutant FVIII-C2 proteins to BO2C11. by Jasper C. Lin (685807)

“…The kinetic range for the Biacore T100 is: k_a constants from ~10³–10⁷ M^-1s^-1; k_d constants from ~10^-5–0.5 s^-1. …”

Over-expression of DN VPS4 in HEK293T cells leads to increased extracellular α-synuclein and parallel decrease in lysosome. by Takafumi Hasegawa (18204)

“…Each fraction was verified by the presence of a specific marker protein: LAMP-1 (late endosome and lysosome), Rab5 (early endosome), Rab11 (recycling endosome), Hsp90 (cytosol), and BSA (culture medium). …”

Environmental swabs with Ct values below 38 yielded enough sequence reads to cover a substantial portion of the SARS-CoV-2 genome. by David A. Coil (7382090)

“…<p>The percent of the SARS-CoV-2 reference genome (isolate Wuhan-Hu-1) covered at ≥ 5X decreased steeply as a function of the mean Ct value (using CDC N1, N2, and Berlin RdRP primers). …”

APOBEC3A is enriched for predicted target sites on the pre-LSU rRNA. by Mason A. McCool (11889842)

“…(B) siAPOBEC3A depletion leads to modest but reproducible decreases in editing frequency at 5 predicted C-to-U variant sites on the pre-rRNA. …”

A combined algorithm to distinguish between IB and NC models based on the differences in binding kinetics and DynR temporal evolution. by Federico Sevlever (8934533)

“…In Examples 2 to 7, the fits are both bad (2, 3, 6) or both good (4, 5, 7), so <b><i>C</i></b> does not allow a decision and further analysis is needed. …”

(A) Rapid light curves, (B) maximum electron transport rates (ETR_max) and (C) minimum saturating irradiances (E_k) derived from the model fitted according to P... by Malte Ostendarp (13217973)

Movement of the shaking codend across five flow velocities from 1.0 to 1.8 kt. by Vang Y. Nguyen (14492737)

(A) Rapid light curves, (B) maximum electron transport rates (ETR_max) and (C) minimum saturating irradiances (E_k) derived from the model fitted according to P... by Malte Ostendarp (13217973)

Coral juvenile abundance of the most abundant taxa across locations and years. by Anna Koester (11805572)

DataSheet1_Deciphering colorectal cancer radioresistance and immune microrenvironment: unraveling the role of EIF5A through single-cell RNA sequencing and machine learning.docx by Yaqi Zhong (19526857)

“…In vivo experiments showed that EIF5A knockdown led to increased infiltration of CD8+ T cells and M1 macrophages, and decreased M2 macrophages and Tregs following radiation therapy, thereby enhancing the radiotherapy response.…”

Role of <i>inhbaa</i> in the partial rescue of vitellogenic growth in <i>bmp15-/-</i> by <i>inha-/-</i>. by Yue Zhai (3141960)

“…The values are expressed as mean ± SEM (n ≥ 5) and analyzed by ANOVA followed by the Tukey HSD for multiple comparisons. …”

SNPs that distinguish the 7 SARS-CoV-2 variants and used as targets for QUILLS assay primers. by Timothy Carroll (3762841)