Supplementary Material for: A Multicenter Pilot Study of a Bronchial Valve for the Treatment of Severe Emphysema by Sterman D.H. (4121239)

“…Highly significant health-related quality of life (HRQL) improvement (–8.2 ± 16.2, mean ± SD change at 6 months) was observed. HRQL improvement was associated with a decreased volume (mean –294 ± 427 ml, p = 0.007) in the treated lobes without visible atelectasis. …”

Dynamics of Ca²⁺ using <i>PLC</i> as a parameter for doses of <i>a</i> ≤ 1 <i>μ</i>g/ml of A<i>β</i>. by Joseph Minicucci (10047331)

“…<p>Model dynamics for the subsystem Eqs (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0246116#pone.0246116.e019" target="_blank">15</a>)–(<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0246116#pone.0246116.e021" target="_blank">17</a>) in terms of <i>PLC</i> and <i>K</i>_<i>s</i>. …”

The roles of miRNA-23a and IL-8 in the radioresistance of NPC cells. by Xin-Hui Li (447760)

“…<p>(A) and (B). A representative clonogenic survival assay shows that transfection of miRNA-23a mimic decreased the radioresistance of NPC CNE2-IR cells. …”

Polypharmacology of <i>N</i>⁶‑(3-Iodobenzyl)­adenosine-5′‑<i>N</i>‑methyluronamide (IB-MECA) and Related A₃ Adenosine Receptor Ligands: Peroxisome Proliferato... by Jinha Yu (1484206)

“…A₃ adenosine receptor (AR) ligands including A₃ AR agonist, <i>N</i>⁶-(3-iodobenzyl)­adenosine-5′-<i>N</i>-methyl­uronamide (<b>1a</b>, IB-MECA) were examined for adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs). …”

CircRNA protein tyrosine phosphatase receptor type a suppresses proliferation and induces apoptosis of lung adenocarcinoma cells via regulation of microRNA-582-3p by Jixin Jiang (12541392)

“…The sites of circRNA_PTPRA/miR-582-3p interaction were identified using StarBase, and validated using a dual-luciferase reporter assay. We observed that circRNA_PTPRA levels were remarkably decreased, and miR-582-3p expression was up-regulated in lung cancer tissues and cells. circRNA_PTPRA directly interacts with miR-582-3p and downregulates miR-582-3p expression in lung cancer cells. …”

Table_5_Effects of Combined Oxytocin and Beta-3 Receptor Agonist (CL 316243) Treatment on Body Weight and Adiposity in Male Diet-Induced Obese Rats.XLS by Melise M. Edwards (11405780)

Presentation1_Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolite... by Margarida L. F. Martins (12194669)

“…However, this was further increased by 1.5-fold in Abcb1a/1b;Abcg2^−/− mice, but not in Abcg2^−/− mice, revealing a stronger effect of mAbcb1a/1b in restricting ibogaine brain penetration. …”

<strong>Figure 5</strong>. <strong>Neither depolymerization nor hyper-stabilization of actin filaments impacts the ATP/ADP ratio of growth cones in continuous NGF.</strong> by Sabrina Holland (16557051)

A model for MEN regulation by PP2A^Cdc55. by Barbara Baro (493729)

“…<p>In early anaphase, FEAR-induced inactivation of the PP2A^Cdc55 promotes the first wave of Cdc14 release and contributes to the accumulation of the Cdc5-phosphorylated form of Bfa1. …”

Image_4_Loss of T-Cell Multifunctionality and TCR-Vβ Repertoire Against Epstein-Barr Virus Is Associated With Worse Prognosis and Clinical Parameters in HIV+ Patients.JPEG by Diana M. Hernández (5816108)

“…Interestingly, these cells were unable to produce IFN-γ and lacked multifunctionality in HIV+ patients. The TCR-Vβ repertoire, which is key for protection against EBV in healthy individuals, was less diverse in HIV⁺ patients due to a lower frequency of TCR-Vβ2⁺, Vβ4⁺, Vβ7.1⁺, Vβ9⁺, Vβ13.6⁺, Vβ14⁺, Vβ17⁺, Vβ22⁺ CD4⁺, Vβ14⁺, and Vβ17⁺ CD8⁺ T cells. …”

Image_2_Loss of T-Cell Multifunctionality and TCR-Vβ Repertoire Against Epstein-Barr Virus Is Associated With Worse Prognosis and Clinical Parameters in HIV+ Patients.JPEG by Diana M. Hernández (5816108)

“…Interestingly, these cells were unable to produce IFN-γ and lacked multifunctionality in HIV+ patients. The TCR-Vβ repertoire, which is key for protection against EBV in healthy individuals, was less diverse in HIV⁺ patients due to a lower frequency of TCR-Vβ2⁺, Vβ4⁺, Vβ7.1⁺, Vβ9⁺, Vβ13.6⁺, Vβ14⁺, Vβ17⁺, Vβ22⁺ CD4⁺, Vβ14⁺, and Vβ17⁺ CD8⁺ T cells. …”

Image_1_Loss of T-Cell Multifunctionality and TCR-Vβ Repertoire Against Epstein-Barr Virus Is Associated With Worse Prognosis and Clinical Parameters in HIV+ Patients.JPEG by Diana M. Hernández (5816108)

“…Interestingly, these cells were unable to produce IFN-γ and lacked multifunctionality in HIV+ patients. The TCR-Vβ repertoire, which is key for protection against EBV in healthy individuals, was less diverse in HIV⁺ patients due to a lower frequency of TCR-Vβ2⁺, Vβ4⁺, Vβ7.1⁺, Vβ9⁺, Vβ13.6⁺, Vβ14⁺, Vβ17⁺, Vβ22⁺ CD4⁺, Vβ14⁺, and Vβ17⁺ CD8⁺ T cells. …”

Image_3_Loss of T-Cell Multifunctionality and TCR-Vβ Repertoire Against Epstein-Barr Virus Is Associated With Worse Prognosis and Clinical Parameters in HIV+ Patients.JPEG by Diana M. Hernández (5816108)

“…Interestingly, these cells were unable to produce IFN-γ and lacked multifunctionality in HIV+ patients. The TCR-Vβ repertoire, which is key for protection against EBV in healthy individuals, was less diverse in HIV⁺ patients due to a lower frequency of TCR-Vβ2⁺, Vβ4⁺, Vβ7.1⁺, Vβ9⁺, Vβ13.6⁺, Vβ14⁺, Vβ17⁺, Vβ22⁺ CD4⁺, Vβ14⁺, and Vβ17⁺ CD8⁺ T cells. …”

The ameliorative effect of CangFu Daotan Decoction on polycystic ovary syndrome of rodent model is associated with m6A methylation and Wnt/β-catenin pathway by Yuwei Zhang (388956)

“…CDD decreased the m6A gene expressions of Mettl3, Mettl14, Fto, Alkbh5, Ythdf1, and Ythdf2 in peripheral blood and ovarian tissue of PCOS rats. …”

Fluid intake and NaCl preference in developing rats. by Jie Qian (565984)

“…Horizontal line denotes NaCl preference ratio of 0.5. In 8-CPT-cAMP treated rats, there was a decrease in H₂O intake (*p = 0.0006) and an increase in NaCl intake (*p = 0.006) relative to control rats. …”

MEK kinase positively and transcriptionally controls CD70 membrane and global expression. by Christine Pich (367328)

“…Actin was used as a loading control <b>(A)</b>. LB39-MEL CD70+ cells were treated with 5 μM of U0126 for 72 h then fixed and processed for immunofluorescence directed against CD70. …”

Typical GEM (solid curve) for the shuffleboard task, obtained as zeros of the goal function Eq (2), plotted in the dimensionless (<i>x</i>, <i>v</i>) body state space. by Joby John (245590)

“…Also shown are the unit vectors tangent and normal to the GEM, and , near a representative operating point <b>x</b>* (Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005118#pcbi.1005118.e019" target="_blank">(5)</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1005118#pcbi.1005118.e024" target="_blank">(6)</a>): small deviations along do not cause error at the target (i.e., they are <i>goal equivalent</i>), while deviations along do (i.e., they are <i>goal relevant</i>). …”

The result of applying the OKO method on ecYeastGEM_v8.3.4 model for overproducing 49 native metabolites of <i>S</i>. <i>cerevisiae</i>. by Zahra Razaghi-Moghadam (1426774)

Fold change in metabolites immediately post-exercise (ranked by VIP>2.5, with q<0.05) by carbohydrate intake from the sugar beverage (sugar) compared to water. by David C. Nieman (322662)

Organization of the actin cytoskeleton and chracterization of focal adhesions on various line dimensions. by Annika Kasten (632603)