FcRn is responsible for pH/antibody-mediated enhanced transcytosis of HIV-1. by Sandeep Gupta (79684)

“…<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003776#s2" target="_blank">Results</a> represent mean+SE of three independent experiments; <i>p</i> = 0.032 comparing wild type and knockdown cells using 2F5 at pH 6.0 (repeated-measures ANCOVA). …”

Effects of mutations in highly conserved motif on OsCERK activity and function. by Fang-Cheng Bi (226018)

“…Equal quantities of protein were added into the 100 µl reaction system, and 1 µl of reaction mix was resolved on a TLC plate after 30 min incubation at 40°C. Purified recombinant ACD5 protein (rACD5) was used as a positive control. …”

ORC2 knockdown enhances PV replication. by Marsha DeSmet (2513767)

“…Values are expressed as mean +/- SEM. * p-value ≤ 0.05. ORC2 shRNA decreased ORC2 protein expression in C33A cells. …”

ID2 expression is inversely correlated to miR-9 and miR-103. by Daniela Annibali (148125)

“…<p>Ectopic expression of miR-9 and miR-103 decreases ID2. (<b>A</b>) Immunoblotting of ID2 in SK-N-BE (upper panel) and SH-SY5Y (lower panel) cells treated with RA for 3, 6 and 10 days. …”

Chronic CSE treatment induced HIF1α accumulation via enhanced lactate production. by Wenyue Sun (134001)

“…<p>A. HIF1α levels in OKF6 cells were determined after 4 h of culture in glucose-free Krebs buffer containing 3 or 5 mmol/L lactate. …”

Age-related reduction of Na, K-ATPase immunoreactivity in the stria vascularis. by Xinping Hao (570986)

“…<p>Sox10 (green) and Na, K-ATPase (31B) immunoreactivity (red) in the StV of a young adult (A–C) and an aged (D–F) mouse. …”

Table1_Placental treatment with insulin-like growth factor 1 via nanoparticle differentially impacts vascular remodeling factors in guinea pig sub-placenta/decidua.DOCX by Baylea N. Davenport (14324355)

“…Additionally, there are no effective in utero treatment options for FGR. We have developed a nanoparticle to deliver human insulin-like 1 growth factor (hIGF-1) in a trophoblast-specific manner which results in increased expression of hIGF-1. …”

Baseline characteristics for pneumonia. by Mathias Aagaard Christensen (19139443)

“…</p><p>Results</p><p>Models were generated for atrial fibrillation, venous thromboembolism and pneumonia as genetics only, clinical features only and a combined model. For venous thromboembolism, the ROC-AUCs were 60.1% [59.6%-60.4%], 63.4% [63.2%-63.4%] and 66.6% [66.2%-66.9%] for the linear models and 51.5% [49.4%-53.4%], 63.2% [61.2%-65.0%] and 62.6% [60.7%-64.5%] for the deep learning SNP, clinical and combined models, respectively. …”

Complexes with Redox-Active Ligands: Synthesis, Structure, and Electrochemical and Photophysical Behavior of the Ru(II) Complex with TTF-Annulated Phenanthroline by Lawrence K. Keniley (1936060)

“…Ru­(II) complexes with chelating ligands, 4′,5′-ethylene­dithio­tetra­thiafulvenyl­[4,5-<i>f</i>]­[1,10]­phenan­throline (<b>L1</b>), 1,3-dithiole-2-thiono­[4,5-<i>f</i>]­[1,10]­phenanthroline (<b>L2</b>), and 1,3-dithiole-2-ono­[4,5-<i>f</i>]­[1,10]­phenanthroline (<b>L3</b>), have been prepared and their structural, electrochemical, and photophysical properties investigated. …”

Expression of CD74, CNTF and bFGF after treatment with EPO or EPO-peptide. by Stephanie Busch (417837)

“…<p>Four week old heterozygous or homozygous male PKD rats (each n = 5) were treated with 0.5 ml/kg body weight DynEpo three times or EPO-like peptide five days a week intraperitoneally for four weeks. …”

miRNA expression microarray. by Masanori Kawano (798368)

“…<p>(A). Heat map of genome-wide miRNA profiles in five ES cell lines and hMSCs. …”

Metabolic risk factors in young adults infected with HIV since childhood compared with the general population by Elise Arrive (5946236)

“…HIV-infected patients had increased mean waist-to-hip ratio and triglycerides to HDL-cholesterol ratio and decreased mean HDL-cholesterol as compared to their counterparts from the general population in both genders. …”

Increased active Rap1 in Rasa3^−/− megakaryocytes. by Patricia Molina-Ortiz (167505)

“…</b> The number of Rasa3^+/+ and Rasa3^−/− adherent megakaryocytes was significantly decreased in GGTI-298 treated cells. Graph represents 2 independent experiments (mean ± SEM). …”

Blocking the C/EBPβ-Thr217 phosphorylation ameliorates the induction of lung fibrosis by Bleomycin. by Martina Buck (82941)

“…After Bleomycin treatment, C/EBPβ^wt mice had moderate to severe lung fibrosis compared to controls, while C/EBPβ-Ala217 mice of the same genetic background had mild or moderate lung fibrosis (mean scores : 2.8+/−0.4 vs. 1.5+/−0.5; <i>n</i>: 10 per group; <i>P</i><0.001). …”

Brine management strategies, technologies, and recovery using adsorption processes by Al-Absi R.S.

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Data_Sheet_1_Mechanical Determinants of the U-Shaped Speed-Energy Cost of Running Relationship.docx by Apolline Carrard (6093833)

“…<p>Purpose: The aim of this study was to investigate the relationship between the energy cost of running (Cr) and speed and its mechanical determinants by comparing running in normal [100% body weight (BW)] and reduced (20% and 60% BW) gravity conditions at several speeds (2.25, 3.17, 4.08, and 5.00 m·s⁻¹) in experienced runners.</p><p>Methods: Twelve experienced runners (24.6 ± 5.4 year) ran on an AlterG treadmill in a partially randomized order at the four running speeds and at the three gravity conditions in order to assess Cr, spatiotemporal parameters, spring-mass characteristics and elastic energy (EL) during running.…”

Temporal Variation of Soil Physical Quality under Conventional and No-Till Systems by Carlos Germán Soracco (5112683)

“…Under NT, most dynamic indicators increase from BS to V6 and decrease again at AH, whereas under CT, they follow a different trend, decreasing from BS to V6, remaining constant until R5, and increasing at AH. …”

Prediction of small for size syndrome after extended hepatectomy: Tissue characterization by relaxometry, diffusion weighted magnetic resonance imaging and magnetization transfer by Christian Eberhardt (315762)

“…An increase in T2 time, again greater in ePH was most pronounced on day 5: 21% for cPH vs. 41% for ePH. ADC and MTR showed a decrease on day 1: 21% for ePH vs. 13% for cPH for ADC, 15% for ePH vs. 11% for cPH for MTR. …”

Randomized clinical trials in dentistry: Risks of bias, risks of random errors, reporting quality, and methodologic quality over the years 1955–2013 by Humam Saltaji (464821)

“…Two thirds of the trials were not described as double blinded (n = 358; 66.3%), while the method of blinding was appropriate in 53% (n = 286) of the trials. We identified a significant decrease over time (1955–2013) in the proportion of trials assessed as having inadequately addressed methodological quality items (P < 0.05) in 30 out of the 40 quality criteria, or as being inadequate (at high or unclear risk of bias) in five domains of the Cochrane risk of bias tool: sequence generation, allocation concealment, incomplete outcome data, other sources of bias, and overall risk of bias.…”

Table1_Baseline Plasma Metabotype Correlates With Direct-Acting Antiviral Therapy Nonresponse for HCV in HIV–HCV Coinfected Patients.XLSX by Gaurav Tripathi (3163251)

“…Post therapy, 62 plasma metabolites (12 upregulated and 50 downregulated, FC±1.5, p < 0.05) differentiated nonresponders from responders and highlighted a significant increase in the steroid and histidine metabolism and significant decrease in tryptophan metabolism and ascorbate and pyruvate metabolism in the nonresponders. …”