Decitabine increased CD34 expression and reduced cell proliferation in transduced human CD34⁺ cells. by Naoya Uchida (267792)

“…<p>(a). To further investigate the decitabine effects on transduction efficiency for human CD34⁺ cells, we added increasing dose of decitabine (0.05, 0.1, 0.2, and 0.5 µM) into media during 24-hour prestimulation (SCF, FLT3L, TPO, and IL3). …”

The protein L-isoaspartyl <i>O</i>-methyltransferase (PCM-1) opposes insulin-like signaling to extend <i>C. elegans</i> lifespan. by Shilpi Khare (187717)

“…<p>Upon binding of the insulin-like ligand to the DAF-2 receptor, the AGE-1 kinase is activated and phosphorylates membrane-bound phosphatidylinositol-4,5-bisphosphate (PIP₂ ), leading to the formation of phosphatidylinositiol-3,4,5-trisphosphate (PIP₃) and recruitment of kinases PDK-1 and AKT-1/AKT-2/SGK-1 complex to the membrane. …”

Effects of CpG-ODN C treatment in <i>Trypanosoma evansi</i> infected and uninfected rabbits. by Parveen Kumar (428921)

“…<p>The rabbits of group I were infected with 1x10⁵<i>T</i>. <i>evansi</i> parasites/animal. …”

Suppressive effect of arginine and sodium fluoride on enamel calcium loss and antibiofilm activity on mature oral microcosm biofilms by Daniela Alejandra Cusicanqui Méndez (5560673)

“…While all treatments resulted in a reduction of α-EPS, 8% arginine showed the most pronounced effect, being the only treatment to decrease β-EPS compared to the control. …”

Climate change has likely already affected global food production by Deepak K. Ray (423970)

“…However, current impacts on a diversity of crops subnationally and implications for food security remains unclear. …”

Grand average DC-EEG and average NIRS traces illustrating characteristic responses evoked by intra-arterial mannitol infusion. by Vesa Kiviniemi (294616)

“…Re-referencing to the distant ECG reference electrode reveals that there is a negative shift throughout the entire scalp. The early transient shifts in the NIRS signals shown for vertebral artery infusions (n = 7) are more delayed and have much smaller amplitudes because NIRS was always measured on the forehead, i.e. they show responses generated in a non-infused brain area.…”

Signaling pathway analysis following MCSF and RANKL treatment. by Muzaffer Cicek (227597)

“…<p><b>A</b>. Osteoclast precursors at day 3 and mature osteoclasts at day 4 were serum-starved and treated with MCSF, RANKL or MCSF+RANKL as indicated for five minutes. …”

Hypoxia restricts larval growth and induces lipid metabolic changes distinct from starvation. by Daniel M. Wong (679523)

“…White arrows point to the larval fat body. [<b>E–G′</b>] Control larvae reared under hypoxic (<i>promE(800)>2xEGFP</i>) and starvation (<i>w¹¹¹⁸</i>) conditions exhibited increased lipid droplet accumulation in the larval fat body (<b>F, G</b>), compared to the control (<b>E</b>). …”

Decomposition of the effects of long-lasting recording with 1 mM ATP-patch clamp-pipettes. by Marta Martini (429411)

“…</b> Same protocols as in <b>A</b>, applied in the same cell 8 min later. Note the drastic decrease in IKD amplitude and the monotonic increase in the I–V curves (as opposed to panel <b>A</b>). …”

The escape response stimulates FLP-18 release from the AVA and RIM. by Jeremy T. Florman (12192010)

“…The spikes in velocity coincide with the initiation of the escape response (D-E) Quantification of fluorescence (arbitrary units–a.u.) in the AVA (D), RIM (E), and coelomocytes (F), at 0-, 1- and 2-hour time points. …”

Clinical Efficacy Results. by Satish Keshav (65388)

“…<p>The percentage of subjects who had a CDAI decrease of at least 70 points is shown at each Induction period study visit after the baseline (A). …”

Evidence of local mechanical control for bone formation and resorption. by Friederike A. Schulte (406501)

“…(D) Mechanical regulation in the CTR group. (E) Sagittal sections through CV6 at (bottom) 0 and (top) 12 weeks after ovariectomy (OVX) (F) OVX causes a strong decrease in BV/TV compared to SHAM-operation (SHM). …”

Table_1_Muscle Loss During Androgen Deprivation Therapy Is Associated With Higher Risk of Non-Cancer Mortality in High-Risk Prostate Cancer.docx by Pai-Kai Chiang (11448058)

“…Body mass index changes were highly and weakly correlated with changes in TATI and SMI, respectively (Spearman ρ for TATI, 0.78, p<0.001; ρ for SMI, 0.27, p=0.003). As a continuous variable, each 1% decrease in SMI was independently associated with a 9% increase in the risk of non-cancer mortality (hazard ratio: 1.09; p=0.007). …”

Termites' effects on arboreal predators. by Robert M. Pringle (248396)

“…Experimental prey supplementation at 30 m essentially equalized mean occupation rates at 10 m and 30 m (red markers; time × proximity interaction: <i>F</i>_1,33 = 7.5, <i>p</i><0.01; <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000377#pbio.1000377.s008" target="_blank">Table S3</a>). …”

PREDICTIVE MAINTENANCE PRACTICES & STANDARDS by Jeremy Wayne Byrd (6661946)

CMV DNAemia specific protein signatures exist pre-CMV DNAemia timepoint and post-CMV. by Tara K. Sigdel (9386207)

“…This analysis resulted in significant changes in 16 proteins, with an increase in their level with CMV infection (n = 11) and a decrease in their level with CMV DNAemia (n = 5). …”

Image_3_Ruxolitinib does not completely abrogate the functional capabilities of TLR4/9 ligand-activated NK cells.jpeg by Carmen Mestre-Durán (7121327)

“…Only the highest doses of ruxolitinib led to a decrease in the pro-inflammatory cytokines tumor necrosis factor α, interferon-γ, interleukin-6, and interleukin-1β. …”

Image3_Impact of the Pilot Volume-Based Drug Purchasing Policy in China: Interrupted Time-Series Analysis with Controls.TIFF by Yilin Chen (678552)

“…Overall, in pilot cities, there was a 35% (95%-CI: 28–41%, p < 0.001) decrease in the purchase spending for all drugs in the first post-policy month, from 8.1 billion CNY estimated in the absence of VBP down to 5.3 billion CNY; in control cities, the change was negligible. …”

Image1_Impact of the Pilot Volume-Based Drug Purchasing Policy in China: Interrupted Time-Series Analysis with Controls.tif by Yilin Chen (678552)

“…Overall, in pilot cities, there was a 35% (95%-CI: 28–41%, p < 0.001) decrease in the purchase spending for all drugs in the first post-policy month, from 8.1 billion CNY estimated in the absence of VBP down to 5.3 billion CNY; in control cities, the change was negligible. …”

DataSheet1_Impact of the Pilot Volume-Based Drug Purchasing Policy in China: Interrupted Time-Series Analysis with Controls.pdf by Yilin Chen (678552)

“…Overall, in pilot cities, there was a 35% (95%-CI: 28–41%, p < 0.001) decrease in the purchase spending for all drugs in the first post-policy month, from 8.1 billion CNY estimated in the absence of VBP down to 5.3 billion CNY; in control cities, the change was negligible. …”