Free energy landscape (FEL) analysis for the SP domain of native PC and its mutant structures over 200 ns MD simulation times. by Mahvash Farajzadeh-Dehkordi (17468232)

Linking Protective <i>GAB2</i> Variants, Increased Cortical <i>GAB2</i> Expression and Decreased Alzheimer’s Disease Pathology by Fanggeng Zou (159980)

“…We next measured <i>GAB2</i> mRNA levels in 249 brains and found that decreased neurofibrillary tangle (r = −0.34, p = 0.0006) and senile plaque counts (r = −0.32, p = 0.001) were both good predictors of increased <i>GAB2</i> mRNA levels albeit that sex (r = −0.28, p = 0.005) may have been a contributing factor. …”

Image_2_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.jpeg by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

DataSheet_1_Gradually decreasing daylength after smoltification induced by “winter signal“ reduced sexual maturation in male Atlantic salmon.docx by Vetle Skjold (17791562)

“…This initial phase was followed by a grow-out period (1 kg–2.5 kg) in seawater (32-ppt salinity) at 13°C for 11 weeks, with exposure to decreasing daylength. …”

Image_1_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.jpeg by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

Image_4_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.jpeg by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

Image_3_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.jpeg by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

RNA sequencing linkage analysis identifies a single base pair change on Chromosome 25 that is tightly linked to the <i>escapist</i> hypersensitive phenotype. by Elelbin A. Ortiz (8655285)

Shedding of PrP is decreased in PrP^CGPIThy-1 L150 mice but increases after RML infection. by Berta Puig (344828)

“…<p>(A) Representative western blot showing shed PrP (detected with our new antibody described in [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007520#ppat.1007520.ref036" target="_blank">36</a>]) and total PrP levels (detected with POM1). …”

Additional file 2 of Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostag... by Fumiaki Kojima (11905683)

“…A significant decrease in food uptake was observed in mPGES-1−/− mice during DSS administration over 7 days, indicating severe symptoms of colitis in mPGES-1−/− mice. …”

Cluster 5—Gene Ontology. by Janaina de Freitas Nascimento (3849415)

“…Furthermore, metacyclics with Pro-Ile and Pro-Val exhibited elevated enzymes linked to lipid and redox metabolism. The results revealed five proteins that were increased and four that were decreased in common in the presence of Pro+BCAAs, indicating their possible participation in key processes related to metacyclogenesis. …”

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

Tun impairs alveolarization in NOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…The decreased radial alveolar counts (RAC; 2.9±0.5 <i>vs</i> 4.8±0.7, n = 11, 5 males and 5 females each group, p<0.001) (<b>A</b>), increased mean linear intercepts (MLI; 77.8±6.8 μm <i>v</i>.…”

24 h exposure to 5 by Kelly M. Kennedy (180156)

“…Viable MCF7 cells show significant decreases with 5 mM CHC (A, #p≤0.004 compared to control (no CHC, no lactate + glucose), ‡‡p < 0.01 compared to 40 mM lactate-treated MCF7 cells, *p = 0.003 compared to all no CHC and low CHC groups). …”

Constitutively nuclear Foxo1 reduced Na_V1.5 expression. by Weike Mao (181121)

“…<p>Western blots showed that overexpression of Foxo1-AA-GFP for 36 hours reduced Na_V1.5 protein level while it increased endogenous Foxo1 expression (A); quantitiation of Na_V1.5 protein level relative to GAPDH revealed that expression of Foxo1-AA-GFP (n = 5) significantly decreased (*p<0.05, at 10 MOI; **p<0.01 at 50 MOI) Na_V1.5 expression compared with 50 MOI GFP (n = 5) (C). …”

Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan, Sirin

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan, Sirin

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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DataSheet_1_Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses.pdf by Chun-Yu Lin (414543)

“…Among 89 DV-infected patients, those with DV infection-related gastrointestinal (GI) bleeding (n = 13, 15% of patients) had significantly higher DEHP exposure than those without GI bleeding (n = 76, 85% of patients), which were 114.2 ng/ml versus 52.5 ng/ml ΣDEHP in urine; p = 0.023). In an in vitro study using cultured human monocyte-derived macrophages (MDMs) to investigate the effects of MEHP, treatment increased IL-1β and TNF-α release but decreased IL-23 release, with negative correlations observed between urine ΣDEHP and serum IL-23 levels in patients. …”

DataSheet_2_Mono-(2-ethylhexyl) phthalate Promotes Dengue Virus Infection by Decreasing IL-23-Mediated Antiviral Responses.docx by Chun-Yu Lin (414543)

“…Among 89 DV-infected patients, those with DV infection-related gastrointestinal (GI) bleeding (n = 13, 15% of patients) had significantly higher DEHP exposure than those without GI bleeding (n = 76, 85% of patients), which were 114.2 ng/ml versus 52.5 ng/ml ΣDEHP in urine; p = 0.023). In an in vitro study using cultured human monocyte-derived macrophages (MDMs) to investigate the effects of MEHP, treatment increased IL-1β and TNF-α release but decreased IL-23 release, with negative correlations observed between urine ΣDEHP and serum IL-23 levels in patients. …”

AT101 causes caspase-independent, non-apoptotic cell death in MPNST cells. by Niroop Kaza (563598)

“…<p>AT101 treated cells demonstrate a concentration- and time-dependent decrease in viability (A, B). …”