Video_1_Resveratrol enhances A1 and hinders A2A adenosine receptors signaling in both HeLa and SH-SY5Y cells: Potential mechanism of its antitumoral action.mp4 by Sonia Muñoz-López (11369454)

“…In the present study, we measured the impact of resveratrol treatment on different adenosinergic pathway components (i.e. adenosine receptors levels, 5’-nucleotidase, adenosine deaminase, and adenylyl cyclase activities, protein kinase A levels, intracellular adenosine and other related metabolites levels) and cell viability and proliferation in HeLa and SH-SY5Y cell lines. …”

Yearly average water balance produced by the BCM2, CNCM3 and MPEH5 GCMs for A1B (top row) and A2 (bottom row) scenarios in comparison with the baseline. by Pamela Louise M. Tolentino (3225021)

GW788388 decreases TGF-β expression and TGF-β activity but has no effect on parasite load in a mouse model of chronic Chagas’ heart disease. by Roberto Rodrigues Ferreira (7109207)

PCAIs suppress 3D NCI-H23 cell invasion. by Matthew D. Gregory (19929096)

Resveratrol Possesses Protective Effects in a Pristane-Induced Lupus Mouse Model by Zhuo-Long Wang (673199)

“…</p><p>Methods</p><p>BALB/c mice received a single intraperitoneal injection of 0.5 ml of pristane on day 1 and then various doses of resveratrol were given to the mice daily starting on day 2 and continuing for seven months. …”

Anthelmintics Derived from the Kinase Inhibitor SGI-1776 for the Treatment of Gastrointestinal Worm Infections by Mostafa A. Elfawal (22430138)

“…We demonstrate the efficacy of optimized compound <b>50</b> as a new oral anthelmintic, which demonstrated better gut restriction properties and significantly reduced the fecundity of T. muris whipworm adults in infected mice. …”

HH-responding cells are lost from the papilla epithelium but retained in connective tissue, and taste bud size, and SHH expression, decrease with duration of HH/GLI repression. by Alexandre N. Ermilov (3365972)

Summary of changes in gene expression in P19[shβ-cat] cultures compared to same-day P19[shControl] cultures after differentiation in DMSO, with and without RA (− = decrease;+ = inc... by Jacob Wong (382569)

“…<p>Summary of changes in gene expression in P19[shβ-cat] cultures compared to same-day P19[shControl] cultures after differentiation in DMSO, with and without RA (− = decrease;+ = increase; NC = No change; NE = not expressed; ND = not determined; * = Enhanced or recovered gene expression due to RA treatment)(Data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057501#pone-0057501-g003" target="_blank">Figs. 3</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057501#pone-0057501-g005" target="_blank">5</a>).…”

Coupled neuronal activity, gGM, PFI, and CSF fMRI signals during burst-suppression anesthesia. by Juliana Zimmermann (10507091)

R117H-7T and R117H-5T function (+/-) ivacaftor: estimates from <i>in vitro</i> measurements of channel function and transcript analysis. by Jessica E. Char (476386)

“…Ivacaftor increases <i>P</i>_<i>O</i> 2–4 fold to give 15% (dashed line) to 30% WT function. (B) R117H-5T. The 5T mutation causes a large decrease in full-length transcripts and when combined with R117H reduces function to ~1.5% (column 3) and to 0.75% when the other allele is non-functional (column 4). …”

Table 3_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…Among females, those with the T allele of ACE2 rs2285666 had a 38% decreased susceptibility to SARS-CoV-2 infection under the dominant [adjusted odds ratio (aOR) = 0.62; 95%CI = 0.45–0.85, P = 0.003] and heterozygous advantage models (aOR = 0.62; 95%CI = 0.45–0.86, P = 0.004), after adjusting for confounders, but not thee recessive model (aOR = 0.41; 95%CI = 0.03–5.22, P = 0.490). …”

Table 1_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…Among females, those with the T allele of ACE2 rs2285666 had a 38% decreased susceptibility to SARS-CoV-2 infection under the dominant [adjusted odds ratio (aOR) = 0.62; 95%CI = 0.45–0.85, P = 0.003] and heterozygous advantage models (aOR = 0.62; 95%CI = 0.45–0.86, P = 0.004), after adjusting for confounders, but not thee recessive model (aOR = 0.41; 95%CI = 0.03–5.22, P = 0.490). …”

Table 2_Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population.docx by Alexander Owusu Boakye (13716966)

“…Among females, those with the T allele of ACE2 rs2285666 had a 38% decreased susceptibility to SARS-CoV-2 infection under the dominant [adjusted odds ratio (aOR) = 0.62; 95%CI = 0.45–0.85, P = 0.003] and heterozygous advantage models (aOR = 0.62; 95%CI = 0.45–0.86, P = 0.004), after adjusting for confounders, but not thee recessive model (aOR = 0.41; 95%CI = 0.03–5.22, P = 0.490). …”

PCAIs suppress NCI-H23 cancer cell migration and invasion. by Matthew D. Gregory (19929096)

Results of a field experiment testing the response of lobsters aggregated in dens to the introduction of a healthy or clinically infected lobster. by Mark J. Butler IV (419498)

Datasheet1_5′-UMP inhibited muscle atrophy due to detraining: a randomized, double-blinded, placebo-controlled, parallel-group comparative study.docx by Mika Inoue (19133983)

“…</p>Results<p>Both groups showed a significant decrease in muscle thickness at MT70. …”

IL-18-induced cell death is partially inhibited by inhibitors of caspase-1 and caspase-3. by Ossama Allam (5043434)

The effect of PCAIs on MAPK pathway protein phosphorylation. by Matthew D. Gregory (19929096)

Cobalamin status in autism and schizophrenia. by Yiting Zhang (391974)

UHRF1 increases bladder cancer cell invasion by inhibiting KiSS1. by Yu Zhang (12946)