Image_9_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…Kv7.4 channels co-expressed with wild-type (WT) CaM show inhibited activation when intracellular calcium levels increase, while Kv7.4 channels co-expressed with CaM₁₂₃₄ or CaM₃ are insensitive to calcium. Mutations C156A, C157A, C158V, R159, and R161A, which are located within the Kv7.4 S2–S3 loop, dramatically facilitate activation of Kv7.4 channels co-expressed with WT CaM but have no effect on activation of Kv7.4 channels co-expressed with CaM₃, indicating that these five mutations decrease the inhibitory effect of Ca²⁺/CaM. …”

Image_1_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…Kv7.4 channels co-expressed with wild-type (WT) CaM show inhibited activation when intracellular calcium levels increase, while Kv7.4 channels co-expressed with CaM₁₂₃₄ or CaM₃ are insensitive to calcium. Mutations C156A, C157A, C158V, R159, and R161A, which are located within the Kv7.4 S2–S3 loop, dramatically facilitate activation of Kv7.4 channels co-expressed with WT CaM but have no effect on activation of Kv7.4 channels co-expressed with CaM₃, indicating that these five mutations decrease the inhibitory effect of Ca²⁺/CaM. …”

Image_3_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…Kv7.4 channels co-expressed with wild-type (WT) CaM show inhibited activation when intracellular calcium levels increase, while Kv7.4 channels co-expressed with CaM₁₂₃₄ or CaM₃ are insensitive to calcium. Mutations C156A, C157A, C158V, R159, and R161A, which are located within the Kv7.4 S2–S3 loop, dramatically facilitate activation of Kv7.4 channels co-expressed with WT CaM but have no effect on activation of Kv7.4 channels co-expressed with CaM₃, indicating that these five mutations decrease the inhibitory effect of Ca²⁺/CaM. …”

<i>ACVR2</i> promoter hypermethylation and LOH in colon cancer specimens and the MSS HT29 cell line and correlation of <i>ACVR2</i> promoter hypermethylation and loss of <i>ACVR2</... by Barbara Jung (155690)

“…C) Six colon cancer cell lines with different microsatellite instability backgrounds (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008308#pone-0008308-t003" target="_blank">Table 3</a>) were analyzed for ACVR2 protein expression using immunoprecipitation techniques. …”

Effects of CTLA4 downregulation on CLL cells. by Amit K. Mittal (440288)

“…RPL13A was used as a housekeeping gene to normalize the cDNA. …”

Supplementary Material for: Palmitic acid modulation of the insulin-like growth factor system in hypothalamic astrocytes and neurons by Guerra-Cantera S. (19170199)

Data_Sheet_1_Short waterlogging events differently affect morphology and photosynthesis of two cucumber (Cucumis sativus L.) cultivars.docx by Omolayo J. Olorunwa (13139154)

“…Specifically, the CO₂ assimilation rate (A) in leaves was significantly reduced and was caused by a corresponding decrease in stomatal conductance (g_s). …”

Supplementary Material for: First European Experience of Shape-Sensing Robotic-assisted bronchoscopy: Learning Curve Analysis by figshare admin karger (2628495)

Large amplitude changes in Pull-type activity for intentional and incidental pulls in RFA-RS neurons. by Akiko Saiki (571879)

“…Horizontal bars (<b>b</b> and <b>b'</b>) correspond to the time windows shown in Fig. 5C. Vertical error bars indicate s.d. values for CFA-RS (orange) and RFA-RS (green) neurons. …”

Insights into the Fragmentation of Aluminum Hydride and Its Effect on Combustion and Agglomeration of HTPB Propellant by Zhoufeng Jiang (1736425)

“…Compared to raw particles, the CCPs (condensed combustion products) of SP2 propellant display a 48% reduction in average size (<i>D</i>₅₀ = 24.5 μm), whereas there is an over 89% decrease in particle size for the CCPs of SP3 propellant (<i>D</i>₅₀ = 5.14 μm). …”

Supplementary materials for 'Systematic review of evidence for the impact and effectiveness of the 1-3-7 strategy for malaria elimination' by Nihal Sogandji (20450902)

“…</p><p dir="ltr">Conclusion: Overall, the 1-3-7 approach was effectively implemented with a concomitant decrease in cases in malaria elimination settings, however, it was not possible to quantify impact as it was not implemented in isolation. …”

Insights into the Fragmentation of Aluminum Hydride and Its Effect on Combustion and Agglomeration of HTPB Propellant by Zhoufeng Jiang (1736425)

“…Compared to raw particles, the CCPs (condensed combustion products) of SP2 propellant display a 48% reduction in average size (<i>D</i>₅₀ = 24.5 μm), whereas there is an over 89% decrease in particle size for the CCPs of SP3 propellant (<i>D</i>₅₀ = 5.14 μm). …”

Insights into the Fragmentation of Aluminum Hydride and Its Effect on Combustion and Agglomeration of HTPB Propellant by Zhoufeng Jiang (1736425)

“…Compared to raw particles, the CCPs (condensed combustion products) of SP2 propellant display a 48% reduction in average size (<i>D</i>₅₀ = 24.5 μm), whereas there is an over 89% decrease in particle size for the CCPs of SP3 propellant (<i>D</i>₅₀ = 5.14 μm). …”

Insights into the Fragmentation of Aluminum Hydride and Its Effect on Combustion and Agglomeration of HTPB Propellant by Zhoufeng Jiang (1736425)

“…Compared to raw particles, the CCPs (condensed combustion products) of SP2 propellant display a 48% reduction in average size (<i>D</i>₅₀ = 24.5 μm), whereas there is an over 89% decrease in particle size for the CCPs of SP3 propellant (<i>D</i>₅₀ = 5.14 μm). …”

Pavement cell shape in receptor-like kinase mutants. by Alice Malivert (11690210)

“…<b>(D)</b> Percentage of increase or decrease in pavement cell circularity from the WT (in blue, <i>Col-0</i> and <i>WS-4</i>), for the microtubule regulator mutants (in orange, <i>nek6-1</i>, <i>spr2-2</i>, <i>tua3</i>, <i>tua4</i>, <i>tua5</i>, and <i>bot1-7</i>) and the receptor-like kinase mutants (in pink, <i>tfr1-1</i>, <i>cvy1-1</i>, <i>fer-4</i>, <i>herk1-1</i>, <i>herk2-1</i>, <i>the1-4</i>, <i>the1-6</i>, <i>wak1-1</i>, <i>wak2-1</i>, <i>wak3-1</i>, <i>wak4-1</i>, and <i>mik2-1</i>). …”

Insights into the Fragmentation of Aluminum Hydride and Its Effect on Combustion and Agglomeration of HTPB Propellant by Zhoufeng Jiang (1736425)

“…Compared to raw particles, the CCPs (condensed combustion products) of SP2 propellant display a 48% reduction in average size (<i>D</i>₅₀ = 24.5 μm), whereas there is an over 89% decrease in particle size for the CCPs of SP3 propellant (<i>D</i>₅₀ = 5.14 μm). …”

Effects of InR on bristle formation. by Annie Dutriaux (458087)

“…In <b>G</b> lack of macrochaetes is observed on <i>sca>hFOXO^3a-TM</i> flies, and in <b>H</b>, it is a decrease of the <i>InR</i> overexpression phenotype (compared to <b>E)</b> in sca><i>Inr</i>,<i>hFOXO^3a-TM</i>. …”

Cell-surface expression of surrogate markers of platelet activation. by Charles P. Mercado (450791)

“…<p>(<b>A</b>) FITC-labeled P-selectin (CD62P) and (<b>B</b>) Alexa Fluor 448-labeled Gp1b show increased and decreased mean fluorescence intensity (unshaded area), respectively, following <i>in vivo</i> 5-HT treatment in contrast to saline-infused littermates (gray shaded area); n = 5–6. …”

Visualization of pathways, interacting network, and validation of selected downstream regulators. by Soumya Panigrahi (188599)

“…In all the immunoblots, lane 1 from no-treatment control cells, lane 2 is from Tat-GFP treated cells, lane 3 is from Tat-apoptin treated cells respectively for both cell lines. STAT5 phosphorylation was significantly inhibited by apoptin indicating that apoptin induced inhibition of Bcr-Abl phosphorylation decreases the activation of STAT5 through phosphorylation. …”

Controlling the Conductance of Atomically Thin Metal Wires with Electrochemical Potential by Xu (3208542)

“…The potential modulation induces a conductance modulation with a phase shift that is always ∼180°, meaning that an increase in the potential always causes a decrease in the conductance. …”