Table_2_Boundary-based registration improves sensitivity for detecting hypoperfusion in sporadic frontotemporal lobar degeneration.DOCX by Sylvia Mihailescu (19454665)

“…Arterial Spin Labeling (ASL) MRI is often acquired in the same session as a structural T1-weighted image (T1w), enabling detection of regional changes in cerebral blood flow (CBF). …”

Table_1_Thalidomide Combined With Azathioprine as Induction and Maintenance Therapy for Azathioprine-Refractory Crohn's Disease Patients.DOCX by Tong Li (206968)

“…Both Crohn's Disease Endoscopic Index of Severity (13.4 ± 4.92 vs. 6.12 ± 5.24, P < 0.001) and Rutgeerts scores (3.23 ± 0.73 vs. 1.77 ± 1.59, P = 0.003) were significantly decreased with the use of combination therapy. Adverse events occurred in 62 (50.8%) patients, but only 13 (10.7%) necessitated therapy discontinuation. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Right Main Bronchus Transection After Blunt Thoracic Trauma by Ivan CH Siu (11978159)

“…<p>Tracheobronchial injury is a rare occurrence in people with blunt thoracic trauma, and it is associated with significant mortality (1). …”

Depletion of endogenous miR-BART9 suppresses the migration and invasiveness of EBV-positive NPC cells. by Chung-Yuan Hsu (528381)

“…<p>(A) LNA-modified anti-BART9 efficiently decreases the level of mature miR-BART9 in EBV-positive HK1-EBV and C666-1 cells. …”

RITA leads to CHK2 phosphorylation and SIRT1 inhibition in head and neck cancer cell lines. by Hui-Ching Chuang (614643)

“…Data are expressed as means ± S.E from three experiments.</p>…”

Stit is required for optimal growth of the wing epithelium. by Fergal O'Farrell (435865)

“…The number of discs examined (<i>n</i>) is indicated. Scale bar, 50 µm. (H) 10 min of EdU incorporation did not show a compartment-specific change in cells entering into S-phase in <i>ap</i>><i>Stit^KD</i> discs versus <i>ap>GFP</i> control discs. …”

Notch activation drives apical constriction and epithelial fold. by Hui-Yu Ku (3185502)

“…(D) Proportions of the three cell populations in <i>hth</i>><i>N</i>^<i>DN</i> EAD. There is a reduction of cells with a decreasing apical area (red), and an increase of cells with a fluctuating apical area (blue). …”

Nutrition regulates <i>gbp1</i> and <i>gbp2</i> expression via TOR signaling in the fat body. by Takashi Koyama (417981)

“…We used the fat bodies from five larvae for each sample and five biologically independent samples for each condition. …”

DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Con... by Melanie Thompson (207727)

“…<div><p>GV-TH-01, a Phase 1 open-label trial of a DNA prime—Modified Vaccinia Ankara (MVA) boost vaccine (GOVX-B11), was undertaken in HIV infected participants on antiretroviral treatment (ART) to evaluate safety and vaccine-elicited T cell responses, and explore the ability of elicited CD8+ T cells to control viral rebound during analytical treatment interruption (TI). …”

datasheet1_The Expiry of Humira® Market Exclusivity and the Entry of Adalimumab Biosimilars in Europe: An Overview of Pricing and National Policy Measures.pdf by Evelien Moorkens (4723848)

“…When reported, discounts/rebates on originator adalimumab after loss of exclusivity ranged from 0% to approximately 26% (Romania), 60% (Poland), 80% (Denmark, Italy, Norway), and 80–90% (Netherlands), leading to actual prices per pen or syringe between €412 (Finland) and €50 – €99 (Netherlands). To leverage competition following entry of biosimilar adalimumab, only a few countries adopted measures specifically for adalimumab in addition to general policies regarding biosimilars. …”

Computational Analysis of Target Site Occurrence by Julius Brennecke (2231)

“…<div><p>(A) Genome-wide occurrence of conserved 5′ seed matches. …”

Toll-Like Receptor-2 Mediates Diet and/or Pathogen Associated Atherosclerosis: Proteomic Findings by Monika Madan (95727)

“…</p><h3>Methods and Results</h3><p>To explore the role of TLR2 in inflammation- and infection-associated atherosclerosis, 10 week-old ApoE^+/−-TLR2^+/+, ApoE^+/−-TLR2^+/− and ApoE^+/−-TLR2^−/− mice were fed either a high fat diet or a regular chow diet. All mice were inoculated intravenously, once per week for 24 consecutive weeks, with 50 µl live <em>Porphyromonas gingivalis</em> (<em>P.g</em>) (10⁷ CFU) or vehicle (normal saline). …”

Thymoquinone loaded nanoemulgel in streptozotocin induced diabetic wound by Urati Anuradha (20306190)

“…<p><b>Aim:</b> To treat diabetic wound healing with a novel Thymoquinone (TQ) loaded nanoformulation by using combination of essentials oils.…”

Image_2_Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children.JPEG by Juan Chen (61123)

“…Covariates associated with voriconazole plasma concentrations and dose requirements were adjusted by using generalized linear mixed-effect models.</p>Results<p>A total of 682 voriconazole steady-state trough concentrations from 91 Chinese pediatric patients were included. …”

4-Octyl itaconate attenuates renal tubular injury in db/db mice by activating Nrf2 and promoting PGC-1α-mediated mitochondrial biogenesis by Muqing Shao (15238576)

“…<i>Irg1</i> knockout mice were generated. db/db mice were treated with 4-octyl itaconate (4-OI, 50 mg/kg), a derivative of itaconate, for 4 weeks. …”

Data_Sheet_1_Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia.PDF by Lelinh Duong (5932946)

“…The immune system plays a critical role in the effectiveness of many anti-cancer therapies in young hosts via tumor-specific T cells. …”

Identification of whole blood mRNA and microRNA biomarkers of tissue damage and immune function resulting from amphetamine exposure or heat stroke in adult male rats by Luísa Camacho (5508251)

“…Most transcripts specific for T-cells decreased 50–70% after AMPH exposure or EIH, with the noted exception of <i>Ccr5</i> and <i>Chst12</i>. …”

Image_1_Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children.JPEG by Juan Chen (61123)

“…Covariates associated with voriconazole plasma concentrations and dose requirements were adjusted by using generalized linear mixed-effect models.</p>Results<p>A total of 682 voriconazole steady-state trough concentrations from 91 Chinese pediatric patients were included. …”

Length-dependent activation in NF trabeculae (<i>n</i> = 9) vs. failing trabeculae with no hypothyroidism (FNH; <i>n</i> = 9) and failing trabeculae with hypothyroidism (FH; <i>n</... by Nancy S. Saad (2615341)

“…<b>(E)</b> RT50 decreased as muscles were shortened from L₁₀₀ to L₈₅ and the degree of shortening was much obvious in NF group. …”